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AT4G13870.1
Subcellular Consensus
(Prediction and Experimental)
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SUBAcon:
nucleus 0.998
What is SUBAcon?
Experimental Localisations and PPI
FP MS/MS PPI
  • PMID:24134884 (2013): cytoskeleton microtubules
SUBAcon links
AGI-AGI relationships
Coexpression PPI
Description (TAIR10) protein_coding : Werner syndrome-like exonuclease
Curator
Summary (TAIR10)
Encodes a protein with homology to the exonuclease domain of hWRN-p of human protein Werner Syndrome Exonuclease (WEX). Forms a complex with the heterodimeric factor Ku. The interaction with KU stimulates WEX exonuclease activity.
Computational
Description (TAIR10)
Werner syndrome-like exonuclease (WRNEXO); FUNCTIONS IN: protein binding, 3'-5' exonuclease activity, nucleic acid binding; INVOLVED IN: nucleobase, nucleoside, nucleotide and nucleic acid metabolic process; LOCATED IN: intracellular; CONTAINS InterPro DOMAIN/s: Polynucleotidyl transferase, ribonuclease H fold (InterPro:IPR012337), 3'-5' exonuclease (InterPro:IPR002562); BEST Arabidopsis thaliana protein match is: Polynucleotidyl transferase, ribonuclease H-like superfamily protein (TAIR:AT4G13885.1); Has 946 Blast hits to 940 proteins in 279 species: Archae - 0; Bacteria - 258; Metazoa - 264; Fungi - 79; Plants - 220; Viruses - 3; Other Eukaryotes - 122 (source: NCBI BLink).
Protein Annotations
EnsemblPlants:AT4G13870EnsemblPlants:AT4G13870.1entrez:827021hmmpanther:PTHR13620
Pfam:PF01612tair10-symbols:ATWEXtair10-symbols:ATWRNEXOtair10-symbols:WEX
tair10-symbols:WRNEXO
Coordinates (TAIR10) chr4:-:8023563..8025542
Molecular Weight (calculated) 31751.50 Da
IEP (calculated) 6.88
GRAVY (calculated) -0.36
Length 285 amino acids
Sequence (TAIR10)
(BLAST)
001: MSSSNWIDDA FTEEELLAID AIEASYNFSR SSSSSSSAAP TVQATTSVHG HEEDPNQIPN NIRRQLPRSI TSSTSYKRFP LSRCRARNFP AMRFGGRILY
101: SKTATEVDKR AMQLIKVLDT KRDESGIAFV GLDIEWRPSF RKGVLPGKVA TVQICVDSNY CDVMHIFHSG IPQSLQHLIE DSTLVKVGIG IDGDSVKLFH
201: DYGVSIKDVE DLSDLANQKI GGDKKWGLAS LTETLVCKEL LKPNRIRLGN WEFYPLSKQQ LQYAATDAYA SWHLYKDLPD AVSGS
See Also
Citation
If you find this resource useful please cite one of the following publications:

Hooper CM, Castleden I, Tanz SK, Aryamanesh, and Millar, AH (2017) SUBA4: the interactive data analysis centre for Arabidopsis subcellular protein locations Nucleic Acids Res. Jan 4;45(D1):D1064-D1074. doi: 10.1093/nar/gkw1041 (PubMed)

Hooper CM, Tanz SK, Castleden IR, Vacher MA, Small ID, Millar AH (2014) "SUBAcon: a consensus algorithm for unifying the subcellular localization data of the Arabidopsis proteome. Bioinformatics." 1;30(23):3356-64. (Bioinformatics) (PubMed)