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AT5G52470.1
Subcellular Consensus
(Prediction and Experimental)

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SUBAcon:
nucleus 1.000
ASURE: nucleus
What is SUBAcon?
What is ASURE?
SUBAcon computations
Experimental Localisations and PPI
FP MS/MS PPI
  • PMID:27122571 (2016): mitochondrion
  • PMID:26572690 (2016): extracellular region plant-type cell wall
  • PMID:25900983 (2015): Golgi Golgi apparatus Golgi membrane
  • PMID:24134884 (2013): cytoskeleton microtubules
  • PMID:23396599 (2013): nucleus nuclear envelope nuclear inner membrane
  • PMID:22318864 (2012): plasma membrane
  • PMID:15496452 (2005): nucleus
  • PMID:14505352 (2003): nucleus
SUBAcon links
AGI-AGI relationships
Coexpression PPI
no PPI data
Description (TAIR10) protein_coding : fibrillarin 1
Curator
Summary (TAIR10)
encodes a fibrillarin, a key nucleolar protein in eukaryotes which associates with box C/D small nucleolar RNAs (snoRNAs) directing 2'-O-ribose methylation of the rRNA. This gene also encodes a novel box C/D snoRNA, U60.1f in its fifth intron that accumulates in seedlings and that their targeted residue on the 25 S rRNA is methylated.
Computational
Description (TAIR10)
fibrillarin 1 (FIB1); FUNCTIONS IN: snoRNA binding; INVOLVED IN: RNA methylation, rRNA processing; LOCATED IN: nucleolus, membrane; EXPRESSED IN: 24 plant structures; EXPRESSED DURING: 13 growth stages; CONTAINS InterPro DOMAIN/s: Fibrillarin (InterPro:IPR000692); BEST Arabidopsis thaliana protein match is: fibrillarin 2 (TAIR:AT4G25630.1); Has 20161 Blast hits to 7736 proteins in 898 species: Archae - 267; Bacteria - 4851; Metazoa - 6936; Fungi - 1342; Plants - 4220; Viruses - 452; Other Eukaryotes - 2093 (source: NCBI BLink).
Protein Annotations
BioGrid:20568EC:2.1.1.-eggNOG:COG1889eggNOG:KOG1596EMBL:AB019226EMBL:AF187871EMBL:AF233443
EMBL:AF263383EMBL:AF265547EMBL:AK230239EMBL:AY139769EMBL:BT004541EMBL:CP002688EnsemblPlants:AT5G52470
EnsemblPlants:AT5G52470.1entrez:835323Gene3D:3.40.50.150GeneID:835323Genevisible:Q9FEF8GO:GO:0000494GO:GO:0003723
GO:GO:0005730GO:GO:0006351GO:GO:0006355GO:GO:0008033GO:GO:0008649GO:GO:0015030GO:GO:0016020
GO:GO:0030515GO:GO:0031167GO:GO:0031428GO:GO:0032040GO:GO:1990258GO:GO:1990259HAMAP:MF_00351
hmmpanther:PTHR10335HOGENOM:HOG000106741InParanoid:Q9FEF8IntAct:Q9FEF8InterPro:IPR000692InterPro:IPR029063KEGG:ath:AT5G52470
KO:K14563OMA:PGVYIVIPaxDb:Q9FEF8Pfam:PF01269Pfam:Q9FEF8PhylomeDB:Q9FEF8PIRSF:PIRSF006540
PRIDE:Q9FEF8PRINTS:PR00052PRO:PR:Q9FEF8ProteinModelPortal:Q9FEF8Proteomes:UP000006548RefSeq:NP_001119418.1RefSeq:NP_568772.3
SMART:SM01206SMR:Q9FEF8STRING:3702.AT5G52470.1SUPFAM:SSF53335SwissPalm:Q9FEF8TAIR:AT5G52470tair10-symbols:ATFBR1
tair10-symbols:ATFIB1tair10-symbols:FBR1tair10-symbols:FIB1tair10-symbols:SKIP7UniGene:At.22470UniProt:Q9FEF8
Coordinates (TAIR10) chr5:+:21294290..21296509
Molecular Weight (calculated) 32831.50 Da
IEP (calculated) 10.80
GRAVY (calculated) -0.39
Length 308 amino acids
Sequence (TAIR10)
(BLAST)
001: MRPPVTGGRG GGGFRGGRDG GGRGFGGGRS FGGGRSGDRG RSGPRGRGRG APRGRGGPPR GGMKGGSKVI VEPHRHAGVF IAKGKEDALV TKNLVPGEAV
101: YNEKRISVQN EDGTKVEYRV WNPFRSKLAA AILGGVDNIW IKPGAKVLYL GAASGTTVSH VSDLVGPEGC VYAVEFSHRS GRDLVNMAKK RTNVIPIIED
201: ARHPAKYRML VGMVDVIFSD VAQPDQARIL ALNASFFLKT GGHFVISIKA NCIDSTVAAE AVFQSEVKKL QQEQFKPAEQ VTLEPFERDH ACVVGGYRMP
301: KKQKTPAS
See Also
Citation
If you find this resource useful please cite one of the following publications:

Hooper CM, Castleden I, Tanz SK, Aryamanesh, and Millar, AH (2017) SUBA4: the interactive data analysis centre for Arabidopsis subcellular protein locations Nucleic Acids Res. Jan 4;45(D1):D1064-D1074. doi: 10.1093/nar/gkw1041 (PubMed)

Hooper CM, Tanz SK, Castleden IR, Vacher MA, Small ID, Millar AH (2014) "SUBAcon: a consensus algorithm for unifying the subcellular localization data of the Arabidopsis proteome. Bioinformatics." 1;30(23):3356-64. (Bioinformatics) (PubMed)