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AT4G33430.1
Subcellular Consensus
(Prediction and Experimental)

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SUBAcon:
plasma membrane 1.000
ASURE: plasma membrane
What is SUBAcon?
What is ASURE?
SUBAcon computations
Predictors External Curations
AmiGO : cytosol 15548744
AmiGO : plasma membrane 0012150928
SwissProt : endoplasmic reticulum 16381842
SwissProt : plasma membrane 16381842
TAIR : cytosol 15548744
TAIR : plasma membrane 14506206
TAIR : plasma membrane 12150928
Experimental Localisations and PPI
FP MS/MS PPI
SUBAcon links
AGI-AGI relationships
Coexpression PPI
Description (TAIR10) protein_coding : BRI1-associated receptor kinase
Curator
Summary (TAIR10)
Leu-rich receptor Serine/threonine protein kinase. Component of BR signaling that interacts with BRI1 in vitro and in vivo to form a heterodimer. Brassinolide-dependent association of BRI1 and BAK1 in vivo. Phosphorylation of both BRI1 and BAK1 on Thr residues was BR dependent. Although BAK1 and BRI1 alone localize in the plasma membrane, when BAK1 and BRI1 are coexpressed, the heterodimer BAK1/BRI1 they form is localized in the endosome.
Computational
Description (TAIR10)
BRI1-associated receptor kinase (BAK1); FUNCTIONS IN: protein binding, protein serine/threonine kinase activity, protein heterodimerization activity, kinase activity; INVOLVED IN: in 6 processes; LOCATED IN: endosome, plasma membrane, protein complex; EXPRESSED IN: 26 plant structures; EXPRESSED DURING: 13 growth stages; CONTAINS InterPro DOMAIN/s: Protein kinase, ATP binding site (InterPro:IPR017441), Protein kinase, catalytic domain (InterPro:IPR000719), Leucine-rich repeat-containing N-terminal domain, type 2 (InterPro:IPR013210), Leucine-rich repeat (InterPro:IPR001611), Serine/threonine-protein kinase-like domain (InterPro:IPR017442), Protein kinase-like domain (InterPro:IPR011009), Serine/threonine-protein kinase, active site (InterPro:IPR008271); BEST Arabidopsis thaliana protein match is: somatic embryogenesis receptor-like kinase 4 (TAIR:AT2G13790.1); Has 30201 Blast hits to 17322 proteins in 780 species: Archae - 12; Bacteria - 1396; Metazoa - 17338; Fungi - 3422; Plants - 5037; Viruses - 0; Other Eukaryotes - 2996 (source: NCBI BLink).
Protein Annotations
BioCyc:ARA:AT4G33430-MONOMERBioCyc:ARA:GQT-1669-MONOMERBioGrid:14764DIP:DIP-34976NEC:2.7.10.1EC:2.7.11.1EMBL:AF384970
EMBL:AL035678EMBL:AL161583EMBL:CP002687EMBL:FJ708762EnsemblPlants:AT4G33430EnsemblPlants:AT4G33430.1entrez:829480
ExpressionAtlas:Q94F62Gene3D:2.60.120.200Gene3D:3.80.10.10GeneID:829480Genevisible:Q94F62GO:GO:0004674GO:GO:0004714
GO:GO:0005524GO:GO:0005886GO:GO:0010008GO:GO:0016021GO:GO:0033612hmmpanther:PTHR27001hmmpanther:PTHR27001:SF1
HOGENOM:HOG000116554InParanoid:Q94F62IntAct:Q94F62InterPro:IPR000719InterPro:IPR001611InterPro:IPR008271InterPro:IPR011009
InterPro:IPR013210InterPro:IPR013320InterPro:IPR017441InterPro:IPR031048InterPro:IPR032675iPTMnet:Q94F62KEGG:04150+2.7.11.1
KEGG:04151+2.7.11.1PANTHER:PTHR27001:SF1PDB:3TL8PDB:3UIMPDB:3ULZPDB:4M7EPDB:4MN8
PDBsum:3TL8PDBsum:3UIMPDBsum:3ULZPDBsum:4M7EPDBsum:4MN8Pfam:PF00069Pfam:PF00560
Pfam:PF07714Pfam:PF08263Pfam:PF13855Pfam:Q94F62Pfscan:PS50011PhylomeDB:Q94F62PIR:T05994
PRIDE:Q94F62PRO:PR:Q94F62PROSITE:PS00107PROSITE:PS00108PROSITE:PS50011ProteinModelPortal:Q94F62Proteomes:UP000006548
RefSeq:NP_567920.1scanprosite:PS00107scanprosite:PS00108SMART:SM00220SMR:Q94F62SUPFAM:SSF52058SUPFAM:SSF56112
TAIR:AT4G33430tair10-symbols:ATBAK1tair10-symbols:ATSERK3tair10-symbols:BAK1tair10-symbols:ELGtair10-symbols:RKS10tair10-symbols:SERK3
TMHMM:TMhelixUniGene:At.376UniProt:Q94F62
Coordinates (TAIR10) chr4:-:16086654..16090288
Molecular Weight (calculated) 68165.00 Da
IEP (calculated) 5.70
GRAVY (calculated) -0.19
Length 615 amino acids
Sequence (TAIR10)
(BLAST)
001: MERRLMIPCF FWLILVLDLV LRVSGNAEGD ALSALKNSLA DPNKVLQSWD ATLVTPCTWF HVTCNSDNSV TRVDLGNANL SGQLVMQLGQ LPNLQYLELY
101: SNNITGTIPE QLGNLTELVS LDLYLNNLSG PIPSTLGRLK KLRFLRLNNN SLSGEIPRSL TAVLTLQVLD LSNNPLTGDI PVNGSFSLFT PISFANTKLT
201: PLPASPPPPI SPTPPSPAGS NRITGAIAGG VAAGAALLFA VPAIALAWWR RKKPQDHFFD VPAEEDPEVH LGQLKRFSLR ELQVASDNFS NKNILGRGGF
301: GKVYKGRLAD GTLVAVKRLK EERTQGGELQ FQTEVEMISM AVHRNLLRLR GFCMTPTERL LVYPYMANGS VASCLRERPE SQPPLDWPKR QRIALGSARG
401: LAYLHDHCDP KIIHRDVKAA NILLDEEFEA VVGDFGLAKL MDYKDTHVTT AVRGTIGHIA PEYLSTGKSS EKTDVFGYGV MLLELITGQR AFDLARLAND
501: DDVMLLDWVK GLLKEKKLEA LVDVDLQGNY KDEEVEQLIQ VALLCTQSSP MERPKMSEVV RMLEGDGLAE RWEEWQKEEM FRQDFNYPTH HPAVSGWIIG
601: DSTSQIENEY PSGPR
See Also
Citation
If you find this resource useful please cite one of the following publications:

Hooper CM, Castleden I, Tanz SK, Aryamanesh, and Millar, AH (2017) SUBA4: the interactive data analysis centre for Arabidopsis subcellular protein locations Nucleic Acids Res. Jan 4;45(D1):D1064-D1074. doi: 10.1093/nar/gkw1041 (PubMed)

Hooper CM, Tanz SK, Castleden IR, Vacher MA, Small ID, Millar AH (2014) "SUBAcon: a consensus algorithm for unifying the subcellular localization data of the Arabidopsis proteome. Bioinformatics." 1;30(23):3356-64. (Bioinformatics) (PubMed)