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AT1G16540.1
Subcellular Consensus
(Prediction and Experimental)
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SUBAcon:
peroxisome 0.855
What is SUBAcon?
Experimental Localisations and PPI
FP MS/MS PPI
SUBAcon links
AGI-AGI relationships
Coexpression PPI
no PPI data
Description (TAIR10) protein_coding : molybdenum cofactor sulfurase (LOS5) (ABA3)
Curator
Summary (TAIR10)
Encodes molybdenum cofactor sulfurase. Involved in Moco biosynthesis. Involved in the conversion of ABA-aldehyde to ABA, the last step of abscisic acid (ABA) biosynthesis. <i>sir</i> loss-of-function mutants are resistant to sirtinol, a modulator of auxin signaling.N terminal domain is similar to bacterial NifS suggesting a common mechanism for sulphur mobilization and transfer. Also involved in protein import into chloroplasts.
Computational
Description (TAIR10)
ABA DEFICIENT 3 (ABA3); CONTAINS InterPro DOMAIN/s: Pyridoxal phosphate-dependent transferase, major domain (InterPro:IPR015424), MOSC, N-terminal beta barrel (InterPro:IPR005303), Aminotransferase, class V/Cysteine desulfurase (InterPro:IPR000192), Molybdenum cofactor sulfurase, C-terminal (InterPro:IPR005302), Pyridoxal phosphate-dependent transferase, major region, subdomain 1 (InterPro:IPR015421); BEST Arabidopsis thaliana protein match is: Molybdenum cofactor sulfurase family protein (TAIR:AT1G30910.1); Has 7940 Blast hits to 7904 proteins in 1914 species: Archae - 94; Bacteria - 5396; Metazoa - 390; Fungi - 394; Plants - 292; Viruses - 1; Other Eukaryotes - 1373 (source: NCBI BLink).
Protein Annotations
BRENDA:2.8.1.9EC:2.8.1.9eggNOG:COG0520eggNOG:COG3217
eggNOG:KOG2142EMBL:AC011808EMBL:AF325457EMBL:AY034895
EMBL:CP002684EnsemblPlants:AT1G16540EnsemblPlants:AT1G16540.1entrez:838224
Gene3D:3.40.640.10Gene3D:3.90.1150.10GeneID:838224Genevisible:Q9C5X8
GO:GO:0005622GO:GO:0006777GO:GO:0006970GO:GO:0008265
GO:GO:0009000GO:GO:0009408GO:GO:0009409GO:GO:0009651
GO:GO:0009688GO:GO:0009734GO:GO:0010118GO:GO:0010182
GO:GO:0016740GO:GO:0018315GO:GO:0030151GO:GO:0030170
GO:GO:0042742GO:GO:0045037Gramene:AT1G16540.1gramene_pathway:2.8.1.-
gramene_pathway:PWY-5354-ARAHAMAP:MF_03050hmmpanther:PTHR14237hmmpanther:PTHR14237:SF19
HOGENOM:HOG000029698InParanoid:Q9C5X8InterPro:IPR000192InterPro:IPR005302
InterPro:IPR005303InterPro:IPR011037InterPro:IPR015421InterPro:IPR015422
InterPro:IPR015424InterPro:IPR028886KEGG:ath:AT1G16540KO:K15631
ncoils:CoilOMA:CQSKVCGPaxDb:Q9C5X8Pfam:PF00266
Pfam:PF03473Pfam:PF03476Pfam:Q9C5X8Pfscan:PS51340
PhylomeDB:Q9C5X8PIR:G86300PRIDE:Q9C5X8PRO:PR:Q9C5X8
PROSITE:PS51340ProteinModelPortal:Q9C5X8Proteomes:UP000006548Reactome:R-ATH-947581
RefSeq:NP_564001.1STRING:3702.AT1G16540.1SUPFAM:0052540SUPFAM:SSF50800
SUPFAM:SSF53383TAIR:AT1G16540tair10-symbols:ABA3tair10-symbols:ACI2
tair10-symbols:ATABA3tair10-symbols:LOS5tair10-symbols:SIR3UniGene:At.18927
UniProt:Q9C5X8
Coordinates (TAIR10) chr1:+:5659465..5665201
Molecular Weight (calculated) 91807.80 Da
IEP (calculated) 6.98
GRAVY (calculated) -0.39
Length 819 amino acids
Sequence (TAIR10)
(BLAST)
001: MEAFLKEFGD YYGYPDGPKN IQEIRDTEFK RLDKGVVYLD HAGSTLYSEL QMEYIFKDFT SNVFGNPHSQ SDISSATSDL IADARHQVLE YFNASPEDYS
101: CLFTSGATAA LKLVGETFPW TQDSNFLYTM ENHNSVLGIR EYALAQGASA CAVDIEEAAN QPGQLTNSGP SIKVKHRAVQ MRNTSKLQKE ESRGNAYNLF
201: AFPSECNFSG LRFNLDLVKL MKENTETVLQ GSPFSKSKRW MVLIDAAKGC ATLPPDLSEY PADFVVLSFY KLFGYPTGLG ALLVRNDAAK LLKKTYFSGG
301: TVAASIADID FVKRRERVEE FFEDGSASFL SIAAIRHGFK LLKSLTPSAI WMHTTSLSIY VKKKLQALRH GNGAAVCVLY GSENLELSSH KSGPTVTFNL
401: KRPDGSWFGY LEVEKLASLS GIQLRTGCFC NPGACAKYLE LSHSELRSNV EAGHICWDDN DVINGKPTGA VRVSFGYMST FEDAKKFIDF IISSFASPPK
501: KTGNGTVVSG RFPQLPSEDL ESKESFPSHY LKSITVYPIK SCAGFSVIRW PLCRTGLLHD REWMVQGLTG EILTQKKVPE MSLIKTFIDL EEGLLSVESS
601: RCEDKLHIRI KSDSYNPRND EFDSHANILE NRNEETRINR WFTNAIGRQC KLLRYSSSTS KDCLNRNKSP GLCRDLESNI NFANEAQFLL ISEESVADLN
701: RRLEAKDEDY KRAHEKLNPH RFRPNLVISG GEPYGEDKWK TVKIGDNHFT SLGGCNRCQM INISNEAGLV KKSNEPLTTL ASYRRVKGKI LFGTLLRYEI
801: DEKRQCWIGV GEEVNPDIE
See Also
Citation
If you find this resource useful please cite one of the following publications:

Hooper CM, Castleden I, Tanz SK, Aryamanesh, and Millar, AH (2017) SUBA4: the interactive data analysis centre for Arabidopsis subcellular protein locations Nucleic Acids Res. Jan 4;45(D1):D1064-D1074. doi: 10.1093/nar/gkw1041 (PubMed)

Hooper CM, Tanz SK, Castleden IR, Vacher MA, Small ID, Millar AH (2014) "SUBAcon: a consensus algorithm for unifying the subcellular localization data of the Arabidopsis proteome. Bioinformatics." 1;30(23):3356-64. (Bioinformatics) (PubMed)