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AT5G35220.1
Subcellular Consensus
(Prediction and Experimental)
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SUBAcon:
plastid 1.000
ASURE: plastid
What is SUBAcon?
Experimental Localisations and PPI
FP MS/MS PPI
  • PMID:31975158 (2020): plastid
  • PMID:31932409 (2020): plastid
  • PMID:31615849 (2019): plastid plastid thylakoid
  • PMID:30135097 (2018): plastid
  • PMID:29967049 (2018): plastid
  • PMID:28865150 (2017): extracellular region plant-type cell wall
  • PMID:27137770 (2016): plastid plastid stroma
  • PMID:24872594 (2014): plastid plastid thylakoid
  • PMID:24124904 (2013): plastid
  • PMID:18431481 (2008): plastid plastid thylakoid
SUBAcon links
AGI-AGI relationships
Coexpression PPI
no PPI data
Description (TAIR10) protein_coding : Peptidase M50 family protein
Curator
Summary (TAIR10)
Membrane-associated and ATP-independent metalloprotease; EGY1 protein contains eight trans-membrane domains at its C-terminus, and carries out beta-casein degradation in an ATP-independent manner. EGY1 is required for development of both thylakoid grana and a well-organized lamellae system in chloroplast. Additionally, EGY1 is required for the accumulation of chlorophyll and chlorophyll a/b binding (CAB) proteins (both PS I and PS II) in chloroplast membranes, and for grana formation and normal chloroplast development. Loss of EGY1 function also has an effect on endodermal plastid biogenesis.
Computational
Description (TAIR10)
ETHYLENE-DEPENDENT GRAVITROPISM-DEFICIENT AND YELLOW-GREEN 1 (EGY1); FUNCTIONS IN: metalloendopeptidase activity; INVOLVED IN: in 9 processes; LOCATED IN: chloroplast, membrane; EXPRESSED IN: hypocotyl endodermis, flower, peduncle, leaf; EXPRESSED DURING: seedling growth; CONTAINS InterPro DOMAIN/s: Peptidase M50 (InterPro:IPR008915); BEST Arabidopsis thaliana protein match is: metalloendopeptidases;zinc ion binding;DNA binding (TAIR:AT5G35210.1); Has 1807 Blast hits to 1807 proteins in 277 species: Archae - 0; Bacteria - 0; Metazoa - 736; Fungi - 347; Plants - 385; Viruses - 0; Other Eukaryotes - 339 (source: NCBI BLink).
Protein Annotations
EC:3.4.24.-eggNOG:COG0750eggNOG:ENOG410IFEGEMBL:AP002031
EMBL:AY050809EMBL:BT001978EMBL:CP002688EnsemblPlants:AT5G35220
EnsemblPlants:AT5G35220.1entrez:833476GeneID:833476Genevisible:Q949Y5
GO:GO:0004222GO:GO:0007275GO:GO:0009416GO:GO:0009507
GO:GO:0009630GO:GO:0009658GO:GO:0009723GO:GO:0009959
GO:GO:0010027GO:GO:0010207GO:GO:0016021GO:GO:0031969
GO:GO:0043157GO:GO:0048564GO:GO:0060359Gramene:AT5G35220.1
hmmpanther:PTHR31412hmmpanther:PTHR31412:SF0HOGENOM:HOG000070550InParanoid:Q949Y5
InterPro:IPR008915KEGG:ath:AT5G35220MEROPS:M50.A02OMA:PYFIPNI
PaxDb:Q949Y5Pfam:PF02163Pfam:Q949Y5PhylomeDB:Q949Y5
PRIDE:Q949Y5PRO:PR:Q949Y5PROSITE:PS00142ProteinModelPortal:Q949Y5
Proteomes:UP000006548RefSeq:NP_198372.1STRING:3702.AT5G35220.1TAIR:AT5G35220
tair10-symbols:EGY1TMHMM:TMhelixUniGene:At.26562UniProt:Q949Y5
Coordinates (TAIR10) chr5:-:13484606..13487546
Molecular Weight (calculated) 59504.00 Da
IEP (calculated) 5.13
GRAVY (calculated) 0.18
Length 548 amino acids
Sequence (TAIR10)
(BLAST)
001: MGTLTSVAFA AAVNIRFRSF HRENIKTTIT TLPKWQKRLC FSSTEDSHRF RIAKCLGNDE NSNRDDSIGE NGETHKSSVV KTATFEEEDE ETSKSSSTTS
101: SSNEFGSDKT SMPSTIDPTY SSFQIDSFKL MELLGPEKVD PADVKLIKDK LFGYSTFWVT KEEPFGDLGE GILFLGNLRG KKEDVFAKLQ RKLVEVASDK
201: YNLFMIEEPN SEGPDPRGGA RVSFGLLRKE VSEPGPTTLW QYVIALILFL LTIGSSVELG IASQINRLPP EVVKYFTDPN AVEPPDMELL YPFVDAALPL
301: AYGVLGILLF HELGHFLAAV PKKVKLSIPY FIPNITLGSF GAITQFKSIL PDRSTKVDIS LAGPFAGAAL SVSMFAVGLF LSTEPDAAND LVQVPSMLFQ
401: GSLLLGLISR ATLGYAALHA ATVSIHPLVI AGWCGLTTTA FNMLPVGCLD GGRAVQGAFG KNALVTFGLS TYVMLGLRVL GGPLALPWGL YVLICQRTPE
501: KPCLNDVTEV GTWRKALVGI ALILVVLTLL PVWDELAEEV GIGLVTTF
See Also
Citation
If you find this resource useful please cite one of the following publications:

Hooper CM, Castleden I, Tanz SK, Aryamanesh, and Millar, AH (2017) SUBA4: the interactive data analysis centre for Arabidopsis subcellular protein locations Nucleic Acids Res. Jan 4;45(D1):D1064-D1074. doi: 10.1093/nar/gkw1041 (PubMed)

Hooper CM, Tanz SK, Castleden IR, Vacher MA, Small ID, Millar AH (2014) "SUBAcon: a consensus algorithm for unifying the subcellular localization data of the Arabidopsis proteome. Bioinformatics." 1;30(23):3356-64. (Bioinformatics) (PubMed)