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AT4G08480.1
Subcellular Consensus
(Prediction and Experimental)
min: heatmap :max

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SUBAcon:
nucleus 0.997
What is SUBAcon?
Experimental Localisations and PPI
FP MS/MS PPI
SUBAcon links
AGI-AGI relationships
Coexpression PPI
Description (TAIR10) protein_coding : mitogen-activated protein kinase kinase kinase 9
Curator
Summary (TAIR10)
Encodes a member of the A1 subgroup of the MEKK (MAPK/ERK kinase kinase) family. MEKK is another name for Mitogen-Activated Protein Kinase Kinase Kinase (MAPKKK or MAP3K). This subgroup has four members: At4g08500 (MEKK1, also known as ARAKIN, MAP3Kb1, MAPKKK8), At4g08480 (MEKK2, also known as MAP3Kb4, MAPKKK9), At4g08470 (MEKK3, also known as MAP3Kb3, MAPKKK10) and At4g12020 (MEKK4, also known as MAP3Kb5, MAPKKK11, WRKY19). Nomenclatures for mitogen-activated protein kinases are described in Trends in Plant Science 2002, 7(7):301.
Computational
Description (TAIR10)
mitogen-activated protein kinase kinase kinase 9 (MAPKKK9); FUNCTIONS IN: protein serine/threonine kinase activity, protein kinase activity, kinase activity, ATP binding; INVOLVED IN: protein amino acid phosphorylation; EXPRESSED IN: 22 plant structures; EXPRESSED DURING: 13 growth stages; CONTAINS InterPro DOMAIN/s: Protein kinase, catalytic domain (InterPro:IPR000719), Serine/threonine-protein kinase domain (InterPro:IPR002290), Serine/threonine-protein kinase-like domain (InterPro:IPR017442), Protein kinase-like domain (InterPro:IPR011009); BEST Arabidopsis thaliana protein match is: MAPK/ERK kinase kinase 1 (TAIR:AT4G08500.1); Has 126354 Blast hits to 124684 proteins in 3992 species: Archae - 124; Bacteria - 13458; Metazoa - 47584; Fungi - 12553; Plants - 31595; Viruses - 535; Other Eukaryotes - 20505 (source: NCBI BLink).
Protein Annotations
BioCyc:ARA:AT4G08480-MONOMEREC:2.7.11.24eggNOG:ENOG410XQGSeggNOG:KOG0198
EMBL:AF076275EMBL:AL161511EMBL:CP002687EnsemblPlants:AT4G08480
EnsemblPlants:AT4G08480.1entrez:826407GeneID:826407Genevisible:O81472
GO:GO:0004707GO:GO:0005524GO:GO:0005622GO:GO:0022622
GO:GO:0031347GO:GO:0045087GO:GO:1902065Gramene:AT4G08480.1
hmmpanther:PTHR24361hmmpanther:PTHR24361:SF318HOGENOM:HOG000239933IntAct:O81472
InterPro:IPR000719InterPro:IPR011009KEGG:ath:AT4G08480OMA:IERKPTI
PaxDb:O81472Pfam:PF00069Pfscan:PS50011PhylomeDB:O81472
PIR:T01835PROSITE:PS50011ProteinModelPortal:O81472Proteomes:UP000006548
RefSeq:NP_192588.1SMR:O81472STRING:3702.AT4G08480.1SUPFAM:SSF56112
TAIR:AT4G08480tair10-symbols:MAPKKK9tair10-symbols:MEKK2UniGene:At.33748
UniProt:O81472
Coordinates (TAIR10) chr4:-:5388253..5391507
Molecular Weight (calculated) 84978.80 Da
IEP (calculated) 5.10
GRAVY (calculated) -0.48
Length 773 amino acids
Sequence (TAIR10)
(BLAST)
001: MKKSSDKSPV RQHDTATQIN SDAVSSSTSF TDSDSTCSFL TPSMEFPDRI SFRRIDFSEA APTGVVLPST SSELTRSNSS ENKIPNEDIS VSTSSRYLVF
101: DKILALMKKS PGRRGDKTSP ARRLDRSDAV RRNIDYDAGE DSSSLLITRS LDFPNRTSFR VDGVDDGEID RIYQYIGVSG PEDFAISSDA WKARMEHERS
201: SSDVVNKLKS LDLDSREAGP SGGVVASSSM NHKFQGHDLS EAGSIGVVVA SNFTLSESNK IENLNSLRDK EIVDGDMVEN RCGIERKPTI LVKSRGYLVH
301: NDDVGVGGGI KGVRPPVLNV PRADKEVVDG GTVESKSGIE WKPTILVKSK GYLVSNDGGI KGVTSPVLNL RPTDKEVVDS GTVENRRGIK GVRPSVLKPP
401: PVMKLPPVDL PGSSWDILTH FAPDSEIVRR PSSSSSSENG CDEEEAEDDK VEKEETGDMF IQLEDTTDEA CSFTTNEGDS SSTVSNTSPI CVSGGSINTS
501: WQKGQLLRQG SFGSVYEAIS EDGDFFAVKE VSLLDQGSQA QECIQQLEGE IALLSQLEHQ NILRYRGTDK DGSNLYIFLE LVTQGSLLEL YRRYQIRDSL
601: ISLYTKQILD GLKYLHHKGF IHRDIKCATI LVDANGTVKL ADFGLAKVSK LNDIKSRKET LFWMAPEVIN RKDNDGYRSP ADIWSLGCTV LEMCTGQIPY
701: SDLEPVEALF RIRRGTLPEV PDTLSLDARH FILKCLKLNP EERPTATELL NHPFVRRPLP SSGSGSTSPL IRR
See Also
Citation
If you find this resource useful please cite one of the following publications:

Hooper CM, Castleden I, Tanz SK, Aryamanesh, and Millar, AH (2017) SUBA4: the interactive data analysis centre for Arabidopsis subcellular protein locations Nucleic Acids Res. Jan 4;45(D1):D1064-D1074. doi: 10.1093/nar/gkw1041 (PubMed)

Hooper CM, Tanz SK, Castleden IR, Vacher MA, Small ID, Millar AH (2014) "SUBAcon: a consensus algorithm for unifying the subcellular localization data of the Arabidopsis proteome. Bioinformatics." 1;30(23):3356-64. (Bioinformatics) (PubMed)