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AT2G46240.1
Subcellular Consensus
(Prediction and Experimental)

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SUBAcon:
nucleus 0.992
What is SUBAcon?
What is ASURE?
SUBAcon computations
Experimental Localisations and PPI
FP MS/MS PPI
SUBAcon links
AGI-AGI relationships
Coexpression PPI
Description (TAIR10) protein_coding : BCL-2-associated athanogene 6
Curator
Summary (TAIR10)
A member of Arabidopsis BAG (Bcl-2-associated athanogene) proteins, plant homologs of mammalian regulators of apoptosis. Expression of BAG6 in leaves was strongly induced by heat stress. Knockout mutants exhibited enhanced susceptibility to fungal pathogen Botrytis cinerea. Plant BAG proteins are multi-functional and remarkably similar to their animal counterparts, as they regulate apoptotic-like processes ranging from pathogen attack, to abiotic stress, to plant development.
Computational
Description (TAIR10)
BCL-2-associated athanogene 6 (BAG6); CONTAINS InterPro DOMAIN/s: Apoptosis regulator, Bcl-2 protein, BAG (InterPro:IPR003103), IQ calmodulin-binding region (InterPro:IPR000048); BEST Arabidopsis thaliana protein match is: BCL-2-associated athanogene 5 (TAIR:AT1G12060.1); Has 21821 Blast hits to 15371 proteins in 1199 species: Archae - 184; Bacteria - 2603; Metazoa - 10110; Fungi - 2300; Plants - 994; Viruses - 95; Other Eukaryotes - 5535 (source: NCBI BLink).
Protein Annotations
BioGrid:4567eggNOG:ENOG410IFYKeggNOG:ENOG410Z1AEEMBL:AC005397EMBL:CP002685EnsemblPlants:AT2G46240EnsemblPlants:AT2G46240.1
entrez:819232Gene3D:1.20.58.120GeneID:819232Genevisible:O82345GO:GO:0005516GO:GO:0006914GO:GO:0006915
GO:GO:0009408GO:GO:0009506GO:GO:0009644GO:GO:0009817GO:GO:0010228GO:GO:0010508GO:GO:0012502
GO:GO:0042542GO:GO:0050832Gramene:AT2G46240.1hmmpanther:PTHR33322hmmpanther:PTHR33322:SF4HOGENOM:HOG000115169InParanoid:O82345
IntAct:O82345InterPro:IPR000048InterPro:IPR003103KEGG:ath:AT2G46240ncoils:CoilOMA:VIEEHEPPaxDb:O82345
Pfam:O82345Pfam:PF02179Pfscan:PS50096Pfscan:PS51035PhylomeDB:O82345PIR:D84900PRIDE:O82345
PRO:PR:O82345PROSITE:PS50096PROSITE:PS51035ProteinModelPortal:O82345Proteomes:UP000006548RefSeq:NP_182147.1SMART:SM00264
STRING:3702.AT2G46240.1SUPFAM:SSF63491TAIR:AT2G46240tair10-symbols:ATBAG6tair10-symbols:BAG6UniGene:At.36537UniProt:O82345
Coordinates (TAIR10) chr2:+:18986586..18989827
Molecular Weight (calculated) 116765.00 Da
IEP (calculated) 4.94
GRAVY (calculated) -0.93
Length 1043 amino acids
Sequence (TAIR10)
(BLAST)
0001: MMPVYMDPSQ PCQMRPQEYY YQGFGNNSQH MAMDAPPPCH GSCVHGNFPA YWPPCYPPQV PYHQCCMNRS AFHPPHASYA PSCYVHPPFP VGYQPWFDVE
0101: KDVPGKHHCG KCSSQMCDLK KDRGVVIEEH EPEIEKGEAV LPVRSTNCPY PIIWIPHENA RNQEYRSSLG LGKHNQPPAE VRAPDNMTIQ KSFPESWRGC
0201: FPFDESSMKS LVQNQDSKKA QNGKTVEAPF DISKFKSLLQ GQDMKEAQIQ KNKEELGQLT YPTSWVPSRR KRDDVEASES SNEDRKKMQN GKTVEYPFDI
0301: SMIKSLIQGQ DVKEAQNQKN KEEPGQVPYP IFWIPSYGKR KDVEASESKE SSNEGRNLES CPSDLHRNEG QITQAKGKEG NFECNVLSDA EEKSSVINIP
0401: VANHLQEPRN IPVKLSENHL PKPTEPTKRI AKNEPVKSTK KEQSSSSSEA SKLPPVCLRV DPLPKERNGG SKSVSHPKRM EKSKETKIAA PLSSKKAESR
0501: TVPEACNVKC EDANAEMKMA EGSLNALRTE KGSVESNSNL QEESNGEIIK PCEAKENREQ PAKKSFTEEE AARIIQSMYR GYDVRRWEPI KKLKEIATVR
0601: EQMGDVKKRI EALEASTDQH IEEKEIVVNG ELVMNLLLKL DAVEGLHPSI REFRKALATE LSSIQDKLDS LKNSCASAEK EAVKEQVEIK SQPSDSPVNL
0701: EHSQLTEENK MVSDTNLEKV LRLSPEEHPM SVLNRTDEKQ AESAAETEEG YGLFETLATD SKQATENAAA ASSTTIPEKI GEVETVVPGN PPSADGNGMT
0801: VTNVEENKAM VVESLEEPIN ELPQMVEETE TNSIRDPENA SEVSEAETNS SENENRKGED DIVLHSEKNV ELSELPVGVI DEETQPLSQD PSSSYTREGN
0901: MTAMDPKTAS QEETEVDHSP NNSKGIGQQT SEPQDEKEQS PETEVIVKEQ PLETEVILNE QAPEPEITEP GISKETKKLM EENQRFKETM ETLVKAGREQ
1001: LEVISKLTSR VKSLEKKLSH KKKTQIRRRA SKPMSVSPTD AVL
See Also
Citation
If you find this resource useful please cite one of the following publications:

Hooper CM, Castleden I, Tanz SK, Aryamanesh, and Millar, AH (2017) SUBA4: the interactive data analysis centre for Arabidopsis subcellular protein locations Nucleic Acids Res. Jan 4;45(D1):D1064-D1074. doi: 10.1093/nar/gkw1041 (PubMed)

Hooper CM, Tanz SK, Castleden IR, Vacher MA, Small ID, Millar AH (2014) "SUBAcon: a consensus algorithm for unifying the subcellular localization data of the Arabidopsis proteome. Bioinformatics." 1;30(23):3356-64. (Bioinformatics) (PubMed)