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AT2G41500.1
Subcellular Consensus
(Prediction and Experimental)

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SUBAcon:
nucleus 1.000
What is SUBAcon?
What is ASURE?
SUBAcon computations
Experimental Localisations and PPI
FP MS/MS PPI
  • PMID:24134884 (2013): cytoskeleton microtubules
SUBAcon links
AGI-AGI relationships
Coexpression PPI
no PPI data
Description (TAIR10) protein_coding : WD-40 repeat family protein / small nuclear ribonucleoprotein Prp4p-related
Curator
Summary (TAIR10)
Encodes LACHESIS (LIS), a protein with seven WD40 repeats. LIS is homologous to the yeast splicing factor PRP4 which is associated with the U4/U6 complex of the spliceosome. LIS is involved in a mechanism that prevents accessory cells from adopting gametic cell fate: lis mutant forms supernumerary egg cells.
Computational
Description (TAIR10)
LACHESIS (LIS); CONTAINS InterPro DOMAIN/s: WD40 repeat 2 (InterPro:IPR019782), WD40 repeat, conserved site (InterPro:IPR019775), Pre-mRNA processing factor 4 (PRP4) like (InterPro:IPR014906), WD40 repeat (InterPro:IPR001680), Splicing factor motif (InterPro:IPR003648), G-protein beta WD-40 repeat, region (InterPro:IPR020472), WD40 repeat-like-containing domain (InterPro:IPR011046), WD40-repeat-containing domain (InterPro:IPR017986), WD40/YVTN repeat-like-containing domain (InterPro:IPR015943), WD40 repeat, subgroup (InterPro:IPR019781); BEST Arabidopsis thaliana protein match is: Transducin/WD40 repeat-like superfamily protein (TAIR:AT2G05720.1); Has 96331 Blast hits to 36444 proteins in 930 species: Archae - 78; Bacteria - 11869; Metazoa - 38307; Fungi - 21059; Plants - 12275; Viruses - 15; Other Eukaryotes - 12728 (source: NCBI BLink).
Protein Annotations
eggNOG:ENOG410XNP8eggNOG:KOG0272EMBL:AC002510EMBL:AC004625EMBL:AK229530EMBL:BT008700EMBL:BT020589
EMBL:CP002685EnsemblPlants:AT2G41500EnsemblPlants:AT2G41500.1entrez:818748Gene3D:2.130.10.10GeneID:818748Genevisible:O22212
GO:GO:0000398GO:GO:0001709GO:GO:0005681GO:GO:0007267GO:GO:0009553GO:GO:0009560GO:GO:0016607
GO:GO:0017070GO:GO:0030621GO:GO:0046540Gramene:AT2G41500.1hmmpanther:PTHR19846HOGENOM:HOG000157615InParanoid:O22212
InterPro:IPR001680InterPro:IPR014906InterPro:IPR015943InterPro:IPR017986InterPro:IPR019775InterPro:IPR020472InterPro:IPR027106
iPTMnet:O22212KEGG:ath:AT2G41500KO:K12662OMA:AKWIASCPANTHER:PTHR19846PaxDb:O22212Pfam:O22212
Pfam:PF00400Pfam:PF08799Pfscan:PS50082Pfscan:PS50294PhylomeDB:O22212PIR:T00806PRIDE:O22212
PRINTS:PR00320PRO:PR:O22212PROSITE:PS00678PROSITE:PS50082PROSITE:PS50294ProteinModelPortal:O22212Proteomes:UP000006548
Reactome:R-ATH-72163RefSeq:NP_181681.1scanprosite:PS00678SMART:SM00320SMART:SM00500SMR:O22212STRING:3702.AT2G41500.1
SUPFAM:0053824SUPFAM:SSF158230SUPFAM:SSF50978TAIR:AT2G41500tair10-symbols:EMB2776tair10-symbols:LISUniGene:At.12395
UniGene:At.42825UniProt:O22212
Coordinates (TAIR10) chr2:-:17304319..17306855
Molecular Weight (calculated) 61845.00 Da
IEP (calculated) 5.43
GRAVY (calculated) -0.51
Length 554 amino acids
Sequence (TAIR10)
(BLAST)
001: MEPNKDDNVS LAATAQISAP PVLQDASSLP GFSAIPPVVP PSFPPPMAPI PMMPHPPVAR PPTFRPPVSQ NGGVKTSDSD SESDDEHIEI SEESKQVRER
101: QEKALQDLLV KRRAAAMAVP TNDKAVRDRL RRLGEPITLF GEQEMERRAR LTQLLTRYDI NGQLDKLVKD HEEDVTPKEE VDDEVLEYPF FTEGPKELRE
201: ARIEIAKFSV KRAAVRIQRA KRRRDDPDED MDAETKWALK HAKHMALDCS NFGDDRPLTG CSFSRDGKIL ATCSLSGVTK LWEMPQVTNT IAVLKDHKER
301: ATDVVFSPVD DCLATASADR TAKLWKTDGT LLQTFEGHLD RLARVAFHPS GKYLGTTSYD KTWRLWDINT GAELLLQEGH SRSVYGIAFQ QDGALAASCG
401: LDSLARVWDL RTGRSILVFQ GHIKPVFSVN FSPNGYHLAS GGEDNQCRIW DLRMRKSLYI IPAHANLVSQ VKYEPQEGYF LATASYDMKV NIWSGRDFSL
501: VKSLAGHESK VASLDITADS SCIATVSHDR TIKLWTSSGN DDEDEEKETM DIDL
See Also
Citation
If you find this resource useful please cite one of the following publications:

Hooper CM, Castleden I, Tanz SK, Aryamanesh, and Millar, AH (2017) SUBA4: the interactive data analysis centre for Arabidopsis subcellular protein locations Nucleic Acids Res. Jan 4;45(D1):D1064-D1074. doi: 10.1093/nar/gkw1041 (PubMed)

Hooper CM, Tanz SK, Castleden IR, Vacher MA, Small ID, Millar AH (2014) "SUBAcon: a consensus algorithm for unifying the subcellular localization data of the Arabidopsis proteome. Bioinformatics." 1;30(23):3356-64. (Bioinformatics) (PubMed)