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AT1G49770.1
Subcellular Consensus
(Prediction and Experimental)

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SUBAcon:
nucleus 1.000
ASURE: nucleus
What is SUBAcon?
What is ASURE?
SUBAcon computations
Experimental Localisations and PPI
FP MS/MS PPI
SUBAcon links
AGI-AGI relationships
Coexpression PPI
no coexpression data no PPI data
Description (TAIR10) protein_coding : basic helix-loop-helix (bHLH) DNA-binding superfamily protein
Curator
Summary (TAIR10)
Encodes a member of the basic helix loop helix family of transcription factors. Loss of RGE1 function causes shriveled seeds that contain small embryos. The cuticle in the embryos does not develop normally, possible due to the adeherence of the endosperm to the developing embryo. RGE1 is expressed in the endosperm surrounding region which directly surrounds the developing embryo, however it exerts its effect non autonomously- in the developing embryo. Mutant seedlings are extremely sensitive to dessication due to the abnormal cuticle.
Computational
Description (TAIR10)
RETARDED GROWTH OF EMBRYO 1 (RGE1); FUNCTIONS IN: DNA binding, sequence-specific DNA binding transcription factor activity; INVOLVED IN: embryo development, regulation of transcription; LOCATED IN: nucleus; EXPRESSED IN: endosperm; CONTAINS InterPro DOMAIN/s: Helix-loop-helix DNA-binding domain (InterPro:IPR001092), Helix-loop-helix DNA-binding (InterPro:IPR011598); BEST Arabidopsis thaliana protein match is: basic helix-loop-helix (bHLH) DNA-binding superfamily protein (TAIR:AT2G22760.1); Has 1071 Blast hits to 1071 proteins in 72 species: Archae - 0; Bacteria - 0; Metazoa - 65; Fungi - 10; Plants - 987; Viruses - 0; Other Eukaryotes - 9 (source: NCBI BLink).
Protein Annotations
BioGrid:26625eggNOG:ENOG410IXGIeggNOG:ENOG410YBAAEMBL:AC011807EMBL:AF488623EMBL:CP002684EnsemblPlants:AT1G49770
EnsemblPlants:AT1G49770.1entrez:841400Gene3D:4.10.280.10GeneID:841400GO:GO:0003677GO:GO:0003700GO:GO:0005634
GO:GO:0006351GO:GO:0006355GO:GO:0009793Gramene:AT1G49770.1hmmpanther:PTHR11514hmmpanther:PTHR11514:SF57HOGENOM:HOG000272699
InParanoid:Q9FXA3InterPro:IPR011598KEGG:ath:AT1G49770ncoils:CoilOMA:LPYPCNDPaxDb:Q9FXA3Pfam:PF00010
Pfam:Q9FXA3Pfscan:PS50888PhylomeDB:Q9FXA3PIR:D96534PRO:PR:Q9FXA3PROSITE:PS50888ProteinModelPortal:Q9FXA3
Proteomes:UP000006548RefSeq:NP_175399.2SMART:SM00353SMR:Q9FXA3STRING:3702.AT1G49770.1SUPFAM:SSF47459TAIR:AT1G49770
tair10-symbols:RGE1tair10-symbols:ZOUUniGene:At.38170UniProt:Q9FXA3
Coordinates (TAIR10) chr1:+:18424578..18426531
Molecular Weight (calculated) 34184.30 Da
IEP (calculated) 6.71
GRAVY (calculated) -0.46
Length 308 amino acids
Sequence (TAIR10)
(BLAST)
001: MTNAQELGQE GFMWGISNSD DSGGGCKRIE KEPLPSHPSH PSPEIQTTTV KKGKKRTKRN DKNHEEESPD HEIHIWTERE RRKKMRDMFS KLHALLPQLP
101: PKADKSTIVD EAVSSIKSLE QTLQKLEMQK LEKLQYSSAS TNTTPTTTFA YAPSSSSSPT ALLTPISNHP IDATATDSYP RAAFLADQVS SSSAAAANLP
201: YPCNDPIVNF DTWSSRNVVL TICGNEAFFN LCVPKHKPGV FTSVCYLFEK YNMEVLFANV SSNVFWSTYV IQAQVNPSCE NQLLGNGLGV VDVFKQVSQE
301: LVLYFSSL
See Also
Citation
If you find this resource useful please cite one of the following publications:

Hooper CM, Castleden I, Tanz SK, Aryamanesh, and Millar, AH (2017) SUBA4: the interactive data analysis centre for Arabidopsis subcellular protein locations Nucleic Acids Res. Jan 4;45(D1):D1064-D1074. doi: 10.1093/nar/gkw1041 (PubMed)

Hooper CM, Tanz SK, Castleden IR, Vacher MA, Small ID, Millar AH (2014) "SUBAcon: a consensus algorithm for unifying the subcellular localization data of the Arabidopsis proteome. Bioinformatics." 1;30(23):3356-64. (Bioinformatics) (PubMed)