AT5G66750.1
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Subcellular Consensus
(Prediction and Experimental) min:  :max.
SUBAcon:nucleus 1.000 ASURE: nucleus What is SUBAcon? |
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| Experimental Localisations and PPI |
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SUBAcon links
AGI-AGI relationships |
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| Description (TAIR10) | protein_coding : chromatin remodeling 1 | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Curator Summary (TAIR10) |
Protein is similar to SWI2/SNF2 chromatin remodeling proteins. DDM1 is appears to act as a chromatin-remodeling ATPase involved in cytosine methylation in CG and non-CG contexts. Involved in gene silencing and maintenance of DNA methylation and histone methylation. Hypomethylation of many genomic regions occurs in ddm1 mutants, and can cause several phenotypic abnormalities, but some loci, such as BONSAI (At1g73177) can be hypermethylated in ddm1 mutants after several generations, leading to different phenotypes. DDM1 might be involved in establishing a heterochromain boundary. A line expressing an RNAi targeted against DDM1 shows some resistance to agrobacterium-mediated root transformation. | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Computational Description (TAIR10) |
chromatin remodeling 1 (CHR1); FUNCTIONS IN: helicase activity, ATPase activity; INVOLVED IN: methylation-dependent chromatin silencing, DNA mediated transformation, transposition, RNA-mediated; LOCATED IN: nucleosome; EXPRESSED IN: 21 plant structures; EXPRESSED DURING: 14 growth stages; CONTAINS InterPro DOMAIN/s: DEAD-like helicase, N-terminal (InterPro:IPR014001), DNA/RNA helicase, C-terminal (InterPro:IPR001650), Helicase, superfamily 1/2, ATP-binding domain (InterPro:IPR014021), SNF2-related (InterPro:IPR000330); BEST Arabidopsis thaliana protein match is: chromatin remodeling factor17 (TAIR:AT5G18620.2); Has 1807 Blast hits to 1807 proteins in 277 species: Archae - 0; Bacteria - 0; Metazoa - 736; Fungi - 347; Plants - 385; Viruses - 0; Other Eukaryotes - 339 (source: NCBI BLink). | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Protein Annotations |
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| Coordinates (TAIR10) | chr5:+:26649050..26652869 | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Molecular Weight (calculated) | 86642.70 Da | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| IEP (calculated) | 6.35 | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| GRAVY (calculated) | -0.50 | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Length | 764 amino acids | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Sequence (TAIR10) (BLAST) |
001: MVSLRSRKVI PASEMVSDGK TEKDASGDSP TSVLNEEENC EEKSVTVVEE EILLAKNGDS SLISEAMAQE EEQLLKLRED EEKANNAGSA VAPNLNETQF 101: TKLDELLTQT QLYSEFLLEK MEDITINGIE SESQKAEPEK TGRGRKRKAA SQYNNTKAKR AVAAMISRSK EDGETINSDL TEEETVIKLQ NELCPLLTGG 201: QLKSYQLKGV KWLISLWQNG LNGILADQMG LGKTIQTIGF LSHLKGNGLD GPYLVIAPLS TLSNWFNEIA RFTPSINAII YHGDKNQRDE LRRKHMPKTV 301: GPKFPIVITS YEVAMNDAKR ILRHYPWKYV VIDEGHRLKN HKCKLLRELK HLKMDNKLLL TGTPLQNNLS ELWSLLNFIL PDIFTSHDEF ESWFDFSEKN 401: KNEATKEEEE KRRAQVVSKL HGILRPFILR RMKCDVELSL PRKKEIIMYA TMTDHQKKFQ EHLVNNTLEA HLGENAIRGQ GWKGKLNNLV IQLRKNCNHP 501: DLLQGQIDGS YLYPPVEEIV GQCGKFRLLE RLLVRLFANN HKVLIFSQWT KLLDIMDYYF SEKGFEVCRI DGSVKLDERR RQIKDFSDEK SSCSIFLLST 601: RAGGLGINLT AADTCILYDS DWNPQMDLQA MDRCHRIGQT KPVHVYRLST AQSIETRVLK RAYSKLKLEH VVIGQGQFHQ ERAKSSTPLE EEDILALLKE 701: DETAEDKLIQ TDISDADLDR LLDRSDLTIT APGETQAAEA FPVKGPGWEV VLPSSGGMLS SLNS |
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| See Also |
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Citation
If you find this resource useful please cite one of the following publications:
Hooper CM, Castleden I, Tanz SK, Aryamanesh, and Millar, AH (2017) SUBA4: the interactive data analysis centre for Arabidopsis subcellular protein locations Nucleic Acids Res. Jan 4;45(D1):D1064-D1074. doi: 10.1093/nar/gkw1041 (PubMed)
Hooper CM, Tanz SK, Castleden IR, Vacher MA, Small ID, Millar AH (2014) "SUBAcon: a consensus algorithm for unifying the subcellular localization data of the Arabidopsis proteome. Bioinformatics." 1;30(23):3356-64. (Bioinformatics) (PubMed)