AT5G64813.1
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Subcellular Consensus
(Prediction and Experimental) min:  :max.
SUBAcon:cytosol 0.500 nucleus 0.500 ASURE: cytosol,nucleus What is SUBAcon? |
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| Experimental Localisations and PPI |
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SUBAcon links
AGI-AGI relationships |
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| Description (TAIR10) | protein_coding : Ras-related small GTP-binding family protein | ||||||||||||||||||||||||||||||||||||||||||||||||||||
| Curator Summary (TAIR10) |
The LIP1 gene encodes a small GTPase that influences the light input pathway of the plant circadian network. An MBP:LIP1 fusion protein has GTP hydrolyzing abilities in vitro. In plants, LIP1 seems to play a negative role in regulating circadian period that can be suppressed by light. LIP1 also seems to negatively affect light-pulse-dependent resetting of the clock, especially during the first portion of the subjective evening. LIP1 expression levels are not significantly affected by the circadian clock in seedlings grown under LL conditions. The levels of the YFP:LIP1 protein expressed under the control of the 35S promoter, shows a low amplitude variation, with protein levels peaking near the beginning of subjective night under LL conditions. In hypocotyl epidermal cells of dark and light-grown seedlings, a YFP:LIP1 fusion protein can be seen in the cytoplasm and the nucleus, and does not cluster in nuclear speckles. LIP1 may also be involved in photomorphogenesis. | ||||||||||||||||||||||||||||||||||||||||||||||||||||
| Computational Description (TAIR10) |
Light Insensitive Period1 (LIP1); FUNCTIONS IN: GTPase activity; INVOLVED IN: circadian regulation of gene expression, photomorphogenesis; LOCATED IN: nucleus, cytoplasm; EXPRESSED IN: 24 plant structures; EXPRESSED DURING: 13 growth stages; CONTAINS InterPro DOMAIN/s: Ras GTPase (InterPro:IPR001806), Small GTPase (InterPro:IPR020851), Ras (InterPro:IPR013753), RNA polymerase sigma factor 54, interaction (InterPro:IPR002078); BEST Arabidopsis thaliana protein match is: Ras-related small GTP-binding family protein (TAIR:AT5G09910.1); Has 30201 Blast hits to 17322 proteins in 780 species: Archae - 12; Bacteria - 1396; Metazoa - 17338; Fungi - 3422; Plants - 5037; Viruses - 0; Other Eukaryotes - 2996 (source: NCBI BLink). | ||||||||||||||||||||||||||||||||||||||||||||||||||||
| Protein Annotations |
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| Coordinates (TAIR10) | chr5:+:25910836..25912625 | ||||||||||||||||||||||||||||||||||||||||||||||||||||
| Molecular Weight (calculated) | 37743.40 Da | ||||||||||||||||||||||||||||||||||||||||||||||||||||
| IEP (calculated) | 9.18 | ||||||||||||||||||||||||||||||||||||||||||||||||||||
| GRAVY (calculated) | -0.52 | ||||||||||||||||||||||||||||||||||||||||||||||||||||
| Length | 342 amino acids | ||||||||||||||||||||||||||||||||||||||||||||||||||||
| Sequence (TAIR10) (BLAST) |
001: MKFWRERERE NKEQILAPLC GQVRVLVVGD SGVGKTSLVH LINKGSSIVR PPQTIGCTVG VKHITYGSPA SSSSSIQGDS ERDFFVELWD VSGHERYKDC 101: RSLFYSQING VIFVHDLSQR RTKTSLQKWA SEVAATGTFS APLPSGGPGG LPVPYIVVGN KADIAAKEGT KGSSGNLVDA ARHWVEKQGL LPSSSEDLPL 201: FESFPGNGGL IAAAKETRYD KEALNKFFRM LIRRRYFSDE LPAASPWSIS PVPTSSSQRL DEITSDDDQF YKRTSFHGDP YKYNNTIPPL PAQRNLTPPP 301: TLYPQQPVST PDNYTIPRYS LSSVQETTNN GSARSKRMDI NV |
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| See Also |
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Citation
If you find this resource useful please cite one of the following publications:
Hooper CM, Castleden I, Tanz SK, Aryamanesh, and Millar, AH (2017) SUBA4: the interactive data analysis centre for Arabidopsis subcellular protein locations Nucleic Acids Res. Jan 4;45(D1):D1064-D1074. doi: 10.1093/nar/gkw1041 (PubMed)
Hooper CM, Tanz SK, Castleden IR, Vacher MA, Small ID, Millar AH (2014) "SUBAcon: a consensus algorithm for unifying the subcellular localization data of the Arabidopsis proteome. Bioinformatics." 1;30(23):3356-64. (Bioinformatics) (PubMed)