suba logo
AT5G64300.1
Subcellular Consensus
(Prediction and Experimental)

min: heatmap :max

.
SUBAcon:
plastid 1.000
What is SUBAcon?
What is ASURE?
SUBAcon computations
Experimental Localisations and PPI
FP MS/MS PPI
SUBAcon links
AGI-AGI relationships
Coexpression PPI
no PPI data
Description (TAIR10) protein_coding : GTP cyclohydrolase II
Curator
Summary (TAIR10)
encodes GTP cyclohydrolase II that can functionally complement E. coli mutant deficient in this gene. It also has 3,4-dihydroxy-2-butanone-4-phosphate synthase activity which makes it a bifunctional enzyme involved in the formation of the pyrimidine and of the carbohydrate from GTP and ribulose-5-phosphate, respectively
Computational
Description (TAIR10)
GTP cyclohydrolase II (GCH); FUNCTIONS IN: 3,4-dihydroxy-2-butanone-4-phosphate synthase activity, GTP cyclohydrolase II activity; INVOLVED IN: riboflavin biosynthetic process; LOCATED IN: chloroplast, membrane; EXPRESSED IN: 22 plant structures; EXPRESSED DURING: 13 growth stages; CONTAINS InterPro DOMAIN/s: GTP cyclohydrolase II (InterPro:IPR000926), DHBP synthase RibB (InterPro:IPR000422), DHBP synthase RibB-like alpha/beta domain (InterPro:IPR017945); BEST Arabidopsis thaliana protein match is: riboflavin biosynthesis protein, putative (TAIR:AT2G22450.1); Has 11690 Blast hits to 11688 proteins in 2324 species: Archae - 209; Bacteria - 6956; Metazoa - 1; Fungi - 397; Plants - 132; Viruses - 0; Other Eukaryotes - 3995 (source: NCBI BLink).
Protein Annotations
BioCyc:ARA:AT5G64300-MONOMERBioCyc:MetaCyc:AT5G64300-MONOMERBioGrid:21793BRENDA:4.1.99.12EC:3.5.4.25EC:4.1.99.12eggNOG:COG0108
eggNOG:COG0807eggNOG:KOG1284EMBL:AB008268EMBL:AJ000053EMBL:CP002688EMBL:D45165EnsemblPlants:AT5G64300
EnsemblPlants:AT5G64300.1entrez:836551Gene3D:3.90.870.10GeneID:836551Genevisible:P47924GO:GO:0003935GO:GO:0005525
GO:GO:0008686GO:GO:0009231GO:GO:0009507GO:GO:0009570GO:GO:0016020GO:GO:0046872Gramene:AT5G64300.1
gramene_pathway:3.5.4.25gramene_pathway:4.1.99.12gramene_pathway:RIBOSYN2-PWYHAMAP:MF_00179HAMAP:MF_00180HAMAP:MF_01283hmmpanther:PTHR21327
hmmpanther:PTHR21327:SF9HOGENOM:HOG000115440InParanoid:P47924InterPro:IPR000422InterPro:IPR000926InterPro:IPR016299InterPro:IPR017945
InterPro:IPR032677iPTMnet:P47924KEGG:00740+3.5.4.25KEGG:00740+3.5.4.25+4.1.99.12KEGG:00740+4.1.99.12KEGG:ath:AT5G64300KO:K14652
MINT:MINT-8063173OMA:LMVDRNTPaxDb:P47924Pfam:P47924Pfam:PF00925Pfam:PF00926PhylomeDB:P47924
PIR:JC4209PRIDE:P47924PRO:PR:P47924ProteinModelPortal:P47924Proteomes:UP000006548RefSeq:NP_201235.4SMR:P47924
STRING:3702.AT5G64300.1SUPFAM:0052081SUPFAM:SSF142695SUPFAM:SSF55821TAIR:AT5G64300tair10-symbols:ATGCHtair10-symbols:ATRIBA1
tair10-symbols:GCHtair10-symbols:RFD1TIGRfam:TIGR00505TIGRfam:TIGR00506TIGRFAMs:TIGR00505TIGRFAMs:TIGR00506UniGene:At.49217
UniPathway:UPA00275UniProt:P47924
Coordinates (TAIR10) chr5:+:25718459..25720790
Molecular Weight (calculated) 59059.50 Da
IEP (calculated) 5.67
GRAVY (calculated) -0.26
Length 543 amino acids
Sequence (TAIR10)
(BLAST)
001: MSSINLSSSS PSTISLSRSR LSQSSTTLLH GLHRVTLPSN HPLSTFSIKT NTGKVKAAVI SREDDLLSFT NGNTPLSNGS LIDDRTEEPL EADSVSLGTL
101: AADSAPAPAN GFVAEDDDFE LDLPTPGFSS IPEAIEDIRQ GKLVVVVDDE DRENEGDLVM AAQLATPEAM AFIVRHGTGI VCVSMKEDDL ERLHLPLMVN
201: QKENEEKLST AFTVTVDAKH GTTTGVSARD RATTILSLAS RDSKPEDFNR PGHIFPLKYR EGGVLKRAGH TEASVDLTVL AGLDPVGVLC EIVDDDGSMA
301: RLPKLREFAA ENNLKVVSIA DLIRYRRKRD KLVERASAAR IPTMWGPFTA YCYRSILDGI EHIAMVKGEI GDGQDILVRV HSECLTGDIF GSARCDCGNQ
401: LALSMQQIEA TGRGVLVYLR GHEGRGIGLG HKLRAYNLQD AGRDTVEANE ELGLPVDSRE YGIGAQIIRD LGVRTMKLMT NNPAKYVGLK GYGLAIVGRV
501: PLLSLITKEN KRYLETKRTK MGHMYGLKFK GDVVEKIESE SES
See Also
Citation
If you find this resource useful please cite one of the following publications:

Hooper CM, Castleden I, Tanz SK, Aryamanesh, and Millar, AH (2017) SUBA4: the interactive data analysis centre for Arabidopsis subcellular protein locations Nucleic Acids Res. Jan 4;45(D1):D1064-D1074. doi: 10.1093/nar/gkw1041 (PubMed)

Hooper CM, Tanz SK, Castleden IR, Vacher MA, Small ID, Millar AH (2014) "SUBAcon: a consensus algorithm for unifying the subcellular localization data of the Arabidopsis proteome. Bioinformatics." 1;30(23):3356-64. (Bioinformatics) (PubMed)