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AT5G62790.1
Subcellular Consensus
(Prediction and Experimental)

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SUBAcon:
plastid 1.000
ASURE: plastid
What is SUBAcon?
What is ASURE?
SUBAcon computations
Experimental Localisations and PPI
FP MS/MS PPI
  • PMID:24361574 (2014): plastid plastid stroma
  • PMID:23851315 (2013): plastid
  • PMID:21531424 (2011): plastid
  • PMID:20061580 (2010): plastid plastid stroma
  • PMID:18633119 (2008): plastid plastid stroma
  • PMID:18431481 (2008): plastid plastid stroma
FP Images

Arabidopsis cell culture (plastidal marker)

At5g62790-GFP
(full-length)
plastidal marker-RFPoverlay

Images by Sandra Tanz
SUBAcon links
AGI-AGI relationships
Coexpression PPI
no PPI data
Description (TAIR10) protein_coding : 1-deoxy-D-xylulose 5-phosphate reductoisomerase
Curator
Summary (TAIR10)
1-Deoxy-d-xylulose 5-phosphate reductoisomerase (DXR) catalyzes the first committed step of the 2-C-methyl-d-erythritol 4-phosphate pathway for isoprenoid biosynthesis. In Arabidopsis, DXR is encoded by a single-copy gene. Arabidopsis DXR is targeted to plastids and localizes into chloroplasts of leaf cells. DXR knockout or strongly silenced lines have a seedling lethal, albino phenotype. Transgenic, partially silenced lines expressing 35S:DXR have a variegated phenotype.
Computational
Description (TAIR10)
1-deoxy-D-xylulose 5-phosphate reductoisomerase (DXR); FUNCTIONS IN: 1-deoxy-D-xylulose-5-phosphate reductoisomerase activity; INVOLVED IN: response to cadmium ion, response to light stimulus, isoprenoid biosynthetic process, isopentenyl diphosphate biosynthetic process, mevalonate-independent pathway; LOCATED IN: chloroplast stroma, chloroplast; EXPRESSED IN: 28 plant structures; EXPRESSED DURING: 14 growth stages; CONTAINS InterPro DOMAIN/s: 1-deoxy-D-xylulose 5-phosphate reductoisomerase, N-terminal (InterPro:IPR013512), 1-deoxy-D-xylulose 5-phosphate reductoisomerase (InterPro:IPR003821), 1-deoxy-D-xylulose 5-phosphate reductoisomerase, C-terminal (InterPro:IPR013644); Has 6813 Blast hits to 6813 proteins in 2049 species: Archae - 0; Bacteria - 4206; Metazoa - 6; Fungi - 0; Plants - 109; Viruses - 0; Other Eukaryotes - 2492 (source: NCBI BLink).
Protein Annotations
BioCyc:ARA:AT5G62790-MONOMERBioCyc:ARA:GQT-1308-MONOMERBioCyc:MetaCyc:AT5G62790-MONOMERBRENDA:1.1.1.267ChEMBL:CHEMBL2285354EC:1.1.1.267eggNOG:COG0743
eggNOG:ENOG410IHSZEMBL:AB009053EMBL:AF148852EMBL:AJ242588EMBL:AY045634EMBL:AY050802EMBL:AY054682
EMBL:AY081453EMBL:AY084775EMBL:AY091405EMBL:AY098952EMBL:CP002688EnsemblPlants:AT5G62790EnsemblPlants:AT5G62790.1
entrez:836400ExpressionAtlas:Q9XFS9Gene3D:3.40.50.720GeneID:836400Genevisible:Q9XFS9GO:GO:0009570GO:GO:0019288
GO:GO:0030604GO:GO:0046872GO:GO:0070402gramene_pathway:1.1.1.267gramene_pathway:NONMEVIPP-PWYgramene_plant_reactome:1119464gramene_plant_reactome:6874388
HAMAP:MF_00183hmmpanther:PTHR30525hmmpanther:PTHR30525:SF2HOGENOM:HOG000007221InParanoid:Q9XFS9InterPro:IPR003821InterPro:IPR013512
InterPro:IPR013644InterPro:IPR016040InterPro:IPR026877iPTMnet:Q9XFS9KEGG:00900+1.1.1.267PANTHER:PTHR30525PaxDb:Q9XFS9
Pfam:PF02670Pfam:PF08436Pfam:PF13288Pfam:Q9XFS9PhylomeDB:Q9XFS9PIR:T52570PRIDE:Q9XFS9
PRO:PR:Q9XFS9ProteinModelPortal:Q9XFS9Proteomes:UP000006548RefSeq:NP_201085.1SMR:Q9XFS9STRING:3702.AT5G62790.2SUPFAM:SSF51735
SUPFAM:SSF55347SUPFAM:SSF69055TAIR:AT5G62790tair10-symbols:DXRtair10-symbols:PDE129TIGRfam:TIGR00243TIGRFAMs:TIGR00243
UniGene:At.23021UniPathway:UPA00056UniProt:Q9XFS9
Coordinates (TAIR10) chr5:-:25214358..25217292
Molecular Weight (calculated) 51966.80 Da
IEP (calculated) 7.05
GRAVY (calculated) -0.09
Length 477 amino acids
Sequence (TAIR10)
(BLAST)
001: MMTLNSLSPA ESKAISFLDT SRFNPIPKLS GGFSLRRRNQ GRGFGKGVKC SVKVQQQQQP PPAWPGRAVP EAPRQSWDGP KPISIVGSTG SIGTQTLDIV
101: AENPDKFRVV ALAAGSNVTL LADQVRRFKP ALVAVRNESL INELKEALAD LDYKLEIIPG EQGVIEVARH PEAVTVVTGI VGCAGLKPTV AAIEAGKDIA
201: LANKETLIAG GPFVLPLANK HNVKILPADS EHSAIFQCIQ GLPEGALRKI ILTASGGAFR DWPVEKLKEV KVADALKHPN WNMGKKITVD SATLFNKGLE
301: VIEAHYLFGA EYDDIEIVIH PQSIIHSMIE TQDSSVLAQL GWPDMRLPIL YTMSWPDRVP CSEVTWPRLD LCKLGSLTFK KPDNVKYPSM DLAYAAGRAG
401: GTMTGVLSAA NEKAVEMFID EKISYLDIFK VVELTCDKHR NELVTSPSLE EIVHYDLWAR EYAANVQLSS GARPVHA
See Also
Citation
If you find this resource useful please cite one of the following publications:

Hooper CM, Castleden I, Tanz SK, Aryamanesh, and Millar, AH (2017) SUBA4: the interactive data analysis centre for Arabidopsis subcellular protein locations Nucleic Acids Res. Jan 4;45(D1):D1064-D1074. doi: 10.1093/nar/gkw1041 (PubMed)

Hooper CM, Tanz SK, Castleden IR, Vacher MA, Small ID, Millar AH (2014) "SUBAcon: a consensus algorithm for unifying the subcellular localization data of the Arabidopsis proteome. Bioinformatics." 1;30(23):3356-64. (Bioinformatics) (PubMed)