AT5G62530.1
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Subcellular Consensus
(Prediction and Experimental) min:  :max.
SUBAcon:mitochondrion 1.000 ASURE: mitochondrion What is SUBAcon? |
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| Experimental Localisations and PPI |
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SUBAcon links
AGI-AGI relationships |
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| Description (TAIR10) | protein_coding : aldehyde dehydrogenase 12A1 | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Curator Summary (TAIR10) |
Encodes mitochondrial Delta-pyrroline-5- carboxylate dehydrogenase. Involved in the catabolism of proline to glutamate. Involved in protection from proline toxicity. Induced at pathogen infection sites. P5CDH and SRO5 (an overlapping gene in the sense orientation) generate 24-nt and 21-nt siRNAs, which together are components of a regulatory loop controlling reactive oxygen species (ROS) production and stress response. | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Computational Description (TAIR10) |
aldehyde dehydrogenase 12A1 (ALDH12A1); FUNCTIONS IN: 3-chloroallyl aldehyde dehydrogenase activity, cobalt ion binding, zinc ion binding, 1-pyrroline-5-carboxylate dehydrogenase activity; INVOLVED IN: oxygen and reactive oxygen species metabolic process, response to salt stress, proline catabolic process to glutamate, proline metabolic process; LOCATED IN: mitochondrion, chloroplast; EXPRESSED IN: 25 plant structures; EXPRESSED DURING: 13 growth stages; CONTAINS InterPro DOMAIN/s: Aldehyde/histidinol dehydrogenase (InterPro:IPR016161), Aldehyde dehydrogenase (InterPro:IPR015590), Aldehyde dehydrogenase, N-terminal (InterPro:IPR016162), Aldehyde dehydrogenase, conserved site (InterPro:IPR016160); BEST Arabidopsis thaliana protein match is: aldehyde dehydrogenase 7B4 (TAIR:AT1G54100.2); Has 30201 Blast hits to 17322 proteins in 780 species: Archae - 12; Bacteria - 1396; Metazoa - 17338; Fungi - 3422; Plants - 5037; Viruses - 0; Other Eukaryotes - 2996 (source: NCBI BLink). | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Protein Annotations |
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| Coordinates (TAIR10) | chr5:-:25099768..25103159 | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Molecular Weight (calculated) | 61776.40 Da | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| IEP (calculated) | 6.72 | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| GRAVY (calculated) | -0.17 | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Length | 556 amino acids | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Sequence (TAIR10) (BLAST) |
001: MYRVFASRAL RAKSLCDKSS TSLASLTLSR LNHSIPFATV DAEELSGAHP AEVQSFVQGK WIGSSNHNTL LDPLNGEPFI KVAEVDESGT QPFVDSLSQC 101: PKHGLHNPFK SPERYLLYGD ISTKAAHMLA LPKVADFFAR LIQRVAPKSY QQAAGEVFVT RKFLENFCGD QVRFLARSFA IPGNHLGQQS HGYRWPYGPV 201: TIVTPFNFPL EIPLLQLMGA LYMGNKPLLK VDSKVSIVME QMMRLLHYCG LPAEDVDFIN SDGKTMNKIL LEANPRMTLF TGSSRVAEKL ALDLKGRIRL 301: EDAGFDWKVL GPDVQEVDYV AWQCDQDAYA CSGQKCSAQS MLFVHENWSK TPLVSKLKEL AERRKLEDLT IGPVLTFTTE AMLEHMENLL QIPGSKLLFG 401: GKELKNHSIP SIYGALEPTA VYVPIEEILK DNKTYELVTK EIFGPFQIVT EYKKDQLPLV LEALERMHAH LTAAVVSNDP IFLQEVIGNS VNGTTYAGLR 501: GRTTGAPQNH WFGPAGDPRG AGIGTPEAIK LVWSCHREVI YDYGPVPQGW ELPPST |
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| See Also |
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Citation
If you find this resource useful please cite one of the following publications:
Hooper CM, Castleden I, Tanz SK, Aryamanesh, and Millar, AH (2017) SUBA4: the interactive data analysis centre for Arabidopsis subcellular protein locations Nucleic Acids Res. Jan 4;45(D1):D1064-D1074. doi: 10.1093/nar/gkw1041 (PubMed)
Hooper CM, Tanz SK, Castleden IR, Vacher MA, Small ID, Millar AH (2014) "SUBAcon: a consensus algorithm for unifying the subcellular localization data of the Arabidopsis proteome. Bioinformatics." 1;30(23):3356-64. (Bioinformatics) (PubMed)