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AT5G62440.1
Subcellular Consensus
(Prediction and Experimental)
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SUBAcon:
nucleus 1.000
What is SUBAcon?
Experimental Localisations and PPI
FP MS/MS PPI
  • PMID:30961429 (2019): nucleus
  • PMID:30783145 (2019): extracellular region plant-type cell wall
  • PMID:28865150 (2017): extracellular region plant-type cell wall
  • PMID:26572690 (2016): extracellular region plant-type cell wall
  • PMID:24134884 (2013): cytoskeleton microtubules
SUBAcon links
AGI-AGI relationships
Coexpression PPI
no PPI data
Description (TAIR10) protein_coding : Protein of unknown function (DUF3223)
Curator
Summary (TAIR10)
Encodes a protein DOMINO1 that belongs to a plant-specific gene family sharing a common motif present in the tomato DEFECTIVE CHLOROPLASTS AND LEAVES (LeDCL) protein. DOMINO1 is located in the nucleus. Arabidopsis embryos carrying the domino1 mutation grow slowly in comparison with wild type embryos and reach only the globular stage at desiccation. The primary defect of the mutation at the cellular level is the large size of the nucleolus that can be observed soon after fertilization in the nuclei of both the embryo and the endosperm. DOMINO1 might have a role in ribosome biogenesis and in determining the rate of cell division.
Computational
Description (TAIR10)
FUNCTIONS IN: molecular_function unknown; INVOLVED IN: nucleologenesis, regulation of cell division, embryo development; LOCATED IN: nucleus; EXPRESSED IN: 24 plant structures; EXPRESSED DURING: 14 growth stages; CONTAINS InterPro DOMAIN/s: Protein of unknown function DUF3223 (InterPro:IPR021602); Has 1122 Blast hits to 800 proteins in 144 species: Archae - 2; Bacteria - 150; Metazoa - 333; Fungi - 187; Plants - 279; Viruses - 3; Other Eukaryotes - 168 (source: NCBI BLink).
Protein Annotations
eggNOG:ENOG410J03TeggNOG:ENOG411208SEMBL:AF371327EMBL:AK175305
EMBL:AK229718EMBL:AY087852EMBL:BT008568EMBL:BT008688
EMBL:CP002688EnsemblPlants:AT5G62440EnsemblPlants:AT5G62440.1entrez:836365
GeneID:836365GO:GO:0005634GO:GO:0009793GO:GO:0017126
GO:GO:0051302Gramene:AT5G62440.1hmmpanther:PTHR33415hmmpanther:PTHR33415:SF3
HOGENOM:HOG000148618IntAct:Q8L557InterPro:IPR021602KEGG:ath:AT5G62440
OMA:TSVAMFDPfam:PF11523PhylomeDB:Q8L557Proteomes:UP000006548
RefSeq:NP_201050.2SMR:Q8L557STRING:3702.AT5G62440.1TAIR:AT5G62440
UniGene:At.29048UniGene:At.69486UniProt:Q8L557
Coordinates (TAIR10) chr5:-:25072620..25073917
Molecular Weight (calculated) 22546.50 Da
IEP (calculated) 5.74
GRAVY (calculated) -0.94
Length 202 amino acids
Sequence (TAIR10)
(BLAST)
001: MAEEQEIVDS LSAEVNPDQK VDMEVETATP KAETGDEKRE REETEEEENG GESKKQKVGE EEKSGPVKLG PKEFVTSVAM FDYFVKFLHF WPTDLDVNKY
101: EHMVLLDLIK KGHSEPEKKI GGGIKTFQVR THPMWKSRCF FLVREDDTAD DFSFRKCVDQ ILPLPENMKT PGANGNGHGG GRGGGGGRRG GRGGGRGGRF
201: RR
See Also
Citation
If you find this resource useful please cite one of the following publications:

Hooper CM, Castleden I, Tanz SK, Aryamanesh, and Millar, AH (2017) SUBA4: the interactive data analysis centre for Arabidopsis subcellular protein locations Nucleic Acids Res. Jan 4;45(D1):D1064-D1074. doi: 10.1093/nar/gkw1041 (PubMed)

Hooper CM, Tanz SK, Castleden IR, Vacher MA, Small ID, Millar AH (2014) "SUBAcon: a consensus algorithm for unifying the subcellular localization data of the Arabidopsis proteome. Bioinformatics." 1;30(23):3356-64. (Bioinformatics) (PubMed)