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AT5G59440.1
Subcellular Consensus
(Prediction and Experimental)
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SUBAcon:
cytosol 0.333
mitochondrion 0.333
nucleus 0.333
ASURE: cytosol,mitochondrion,nucleus
What is SUBAcon?
Experimental Localisations and PPI
FP MS/MS PPI
SUBAcon links
AGI-AGI relationships
Coexpression PPI
no PPI data
Description (TAIR10) protein_coding : P-loop containing nucleoside triphosphate hydrolases superfamily protein
Curator
Summary (TAIR10)
Encodes thymidylate kinase which exists in two isoforms in plants. The longer variant of 263 amino acids with a N-terminal extension that is required for localization to the mitochondrion. The second isoform of 224 residues is localized to the cytoplasm and nucleoplasm. Peak of expression occurs during G1/S phase transition.
Computational
Description (TAIR10)
ZEUS1 (ZEU1); FUNCTIONS IN: thymidylate kinase activity, ATP binding; INVOLVED IN: dTDP biosynthetic process, pyrimidine deoxyribonucleoside interconversion, anaerobic respiration; LOCATED IN: nucleoplasm, mitochondrion, cytoplasm; EXPRESSED IN: 26 plant structures; EXPRESSED DURING: 13 growth stages; CONTAINS InterPro DOMAIN/s: Thymidylate kinase (InterPro:IPR018094), Thymidylate kinase-like (InterPro:IPR000062), Thymidylate kinase, conserved site (InterPro:IPR018095); Has 5519 Blast hits to 5517 proteins in 2216 species: Archae - 247; Bacteria - 3946; Metazoa - 202; Fungi - 154; Plants - 114; Viruses - 143; Other Eukaryotes - 713 (source: NCBI BLink).
Protein Annotations
BioCyc:ARA:AT5G59440-MONOMERBioCyc:ARA:GQT-1477-MONOMERBioCyc:ARA:GQT-1478-MONOMERBioCyc:MetaCyc:AT5G59440-MONOMER
eggNOG:COG0125eggNOG:KOG3327EMBL:AK226501EMBL:CP002688
EnsemblPlants:AT5G59440EnsemblPlants:AT5G59440.1entrez:836063ExpressionAtlas:Q0WW55
Gene3D:3.40.50.300GeneID:836063GO:GO:0004798GO:GO:0005524
GO:GO:0006233Gramene:AT5G59440.1gramene_pathway:2.7.4.9gramene_pathway:PWY0-166
HAMAP:MF_00165hmmpanther:PTHR10344HOGENOM:HOG000229079InterPro:IPR018094
InterPro:IPR018095InterPro:IPR027417KEGG:00240+2.7.4.9ncoils:Coil
Pfam:PF02223PhylomeDB:Q0WW55PROSITE:PS01331Proteomes:UP000006548
Reactome:R-ATH-499943RefSeq:NP_851222.1scanprosite:PS01331SMR:Q0WW55
STRING:3702.AT5G59440.3SUPFAM:SSF52540TAIR:AT5G59440tair10-symbols:ATTMPK.1
tair10-symbols:ZEU1TIGRfam:TIGR00041TIGRFAMs:TIGR00041UniGene:At.19783
UniProt:Q0WW55
Coordinates (TAIR10) chr5:+:23971533..23972729
Molecular Weight (calculated) 29551.20 Da
IEP (calculated) 8.45
GRAVY (calculated) -0.37
Length 263 amino acids
Sequence (TAIR10)
(BLAST)
001: MKRICSVSSV QLFSRSFRAL ASPRSLNYPL QCIKRSSVRM ESSNFSSGVR TESSVKPRGA LIVLEGLDRS GKSTQCAKLL SFLNGLGHPT ELWRFPDRET
101: SVGQMISAYL SNKSQLDDHT IHLLFSANRW EKRSLMEEKL KTGTTLIVDR YSYSGVAFSS AKGLDIEWCK APEIGLLAPD SVLYLDISPE RAAERGGYGD
201: ERYERVEFQK KVADFYQTLG DSSWKIINAS DAMEEVEKKI QQVVLDQVKE CTEGKPLSLL WSS
See Also
Citation
If you find this resource useful please cite one of the following publications:

Hooper CM, Castleden I, Tanz SK, Aryamanesh, and Millar, AH (2017) SUBA4: the interactive data analysis centre for Arabidopsis subcellular protein locations Nucleic Acids Res. Jan 4;45(D1):D1064-D1074. doi: 10.1093/nar/gkw1041 (PubMed)

Hooper CM, Tanz SK, Castleden IR, Vacher MA, Small ID, Millar AH (2014) "SUBAcon: a consensus algorithm for unifying the subcellular localization data of the Arabidopsis proteome. Bioinformatics." 1;30(23):3356-64. (Bioinformatics) (PubMed)