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AT5G58140.1
Subcellular Consensus
(Prediction and Experimental)
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SUBAcon:
plasma membrane 1.000
ASURE: plasma membrane
What is SUBAcon?
Experimental Localisations and PPI
FP MS/MS PPI
  • PMID:30962257 (2019): plastid
  • PMID:30447334 (2019): plasma membrane
  • PMID:27943495 (2017): mitochondrion
  • PMID:26781341 (2016): plasma membrane
  • PMID:25900983 (2015): Golgi trans-Golgi network
  • PMID:25900983 (2015): Golgi trans-Golgi network early endosome
  • PMID:25900983 (2015): Golgi trans-Golgi network multivesicular body
  • PMID:25641898 (2015): plasma membrane
  • PMID:23673981 (2013): plastid plastid stroma plastoglobules
  • PMID:22215637 (2012): plasma membrane
  • PMID:22182420 (2012): endoplasmic reticulum
  • PMID:21988472 (2012): plant-type vacuole plant-type vacuole membrane
  • PMID:20061580 (2010): plastid plastid envelope
  • PMID:19000159 (2009): plasma membrane
  • PMID:18686298 (2008): plant-type vacuole plant-type vacuole membrane
  • PMID:17644812 (2007): plasma membrane
SUBAcon links
AGI-AGI relationships
Coexpression PPI
Description (TAIR10) protein_coding : phototropin 2
Curator
Summary (TAIR10)
Membrane-bound protein serine/threonine kinase that functions as blue light photoreceptor in redundancy with PHO1. Involved in stomatal opening, chloroplast movement and phototropism. Mediates blue light-induced growth enhancements. PHOT1 and PHOT2 mediate blue light-dependent activation of the plasma membrane H+-ATPase in guard cell protoplasts. PHOT2 possesses two LOV (LOV1 and LOV2, for light-oxygen-voltage-sensing) domains involved in FMN-binding and a C-terminus forming a serine/threonine kinase domain. LOV2 acts as an inhibitor of phototropin kinase in the dark, and light cancels the inhibition through cysteine-FMN adduct formation. LOV1 in contrast acts as an attenuator of photoactivation. Localized to the Golgi apparatus under the induction of blue light.
Computational
Description (TAIR10)
phototropin 2 (PHOT2); FUNCTIONS IN: protein serine/threonine kinase activity, FMN binding, kinase activity, blue light photoreceptor activity; INVOLVED IN: in 7 processes; LOCATED IN: Golgi apparatus, plasma membrane, membrane; EXPRESSED IN: 26 plant structures; EXPRESSED DURING: 13 growth stages; CONTAINS InterPro DOMAIN/s: PAC motif (InterPro:IPR001610), Protein kinase, ATP binding site (InterPro:IPR017441), Serine/threonine-protein kinase domain (InterPro:IPR002290), PAS fold (InterPro:IPR013767), PAS (InterPro:IPR000014), PAS-associated, C-terminal (InterPro:IPR000700), Serine/threonine-protein kinase-like domain (InterPro:IPR017442), Protein kinase-like domain (InterPro:IPR011009), Serine/threonine-protein kinase, active site (InterPro:IPR008271), Protein kinase, catalytic domain (InterPro:IPR000719), Tyrosine-protein kinase, catalytic domain (InterPro:IPR020635); BEST Arabidopsis thaliana protein match is: phototropin 1 (TAIR:AT3G45780.2); Has 116748 Blast hits to 111792 proteins in 3621 species: Archae - 310; Bacteria - 19900; Metazoa - 40386; Fungi - 12616; Plants - 24323; Viruses - 447; Other Eukaryotes - 18766 (source: NCBI BLink).
Protein Annotations
BioCyc:ARA:AT5G58140-MONOMERBioCyc:ARA:GQT-2687-MONOMERBioCyc:ARA:GQT-2830-MONOMERBioCyc:ARA:GQT-2831-MONOMER
BioGrid:21170DIP:DIP-53468NEC:2.7.11.1eggNOG:COG2202
eggNOG:ENOG410IH6NEMBL:AB019228EMBL:AB024029EMBL:AF053941
EMBL:AY093141EMBL:BT008901EMBL:CP002688EMBL:U79744
EnsemblPlants:AT5G58140EnsemblPlants:AT5G58140.1EnsemblPlants:AT5G58140.2entrez:835926
EvolutionaryTrace:P93025ExpressionAtlas:P93025GeneID:835926Genevisible:P93025
GO:GO:0000155GO:GO:0004674GO:GO:0005524GO:GO:0005794
GO:GO:0005886GO:GO:0007623GO:GO:0009637GO:GO:0009638
GO:GO:0009735GO:GO:0009785GO:GO:0009882GO:GO:0009902
GO:GO:0010118GO:GO:0010181GO:GO:0010362GO:GO:0016020
GO:GO:0016301GO:GO:0018298GO:GO:0035556GO:GO:0042802
GO:GO:0046777hmmpanther:PTHR24351hmmpanther:PTHR24351:SF81HOGENOM:HOG000265679
InParanoid:P93025IntAct:P93025InterPro:IPR000014InterPro:IPR000700
InterPro:IPR000719InterPro:IPR001610InterPro:IPR008271InterPro:IPR011009
InterPro:IPR017441iPTMnet:P93025MINT:MINT-6823418OMA:PRIPDNP
PaxDb:P93025PDB:2Z6DPDB:4EEPPDB:4EER
PDB:4EESPDB:4EETPDB:4EEUPDB:4NXB
PDB:4NXEPDB:4NXFPDB:4NXGPDBsum:2Z6D
PDBsum:4EEPPDBsum:4EERPDBsum:4EESPDBsum:4EET
PDBsum:4EEUPDBsum:4NXBPDBsum:4NXEPDBsum:4NXF
PDBsum:4NXGPfam:P93025Pfam:PF00069Pfam:PF13426
Pfscan:PS50011Pfscan:PS50112Pfscan:PS50113PhylomeDB:P93025
PIR:T51600PRIDE:P93025PRO:PR:P93025PROSITE:PS00107
PROSITE:PS00108PROSITE:PS50011PROSITE:PS50112PROSITE:PS50113
ProteinModelPortal:P93025Proteomes:UP000006548RefSeq:NP_851210.1RefSeq:NP_851211.1
scanprosite:PS00107scanprosite:PS00108SMART:SM00086SMART:SM00091
SMART:SM00220SMR:P93025STRING:3702.AT5G58140.1SUPFAM:SSF55785
SUPFAM:SSF56112TAIR:AT5G58140tair10-symbols:NPL1tair10-symbols:PHOT2
TIGRfam:TIGR00229TIGRFAMs:TIGR00229UniGene:At.22044UniGene:At.72500
UniProt:P93025
Coordinates (TAIR10) chr5:+:23524771..23529993
Molecular Weight (calculated) 102478.00 Da
IEP (calculated) 7.45
GRAVY (calculated) -0.56
Length 915 amino acids
Sequence (TAIR10)
(BLAST)
001: MERPRAPPSP LNDAESLSER RSLEIFNPSS GKETHGSTSS SSKPPLDGNN KGSSSKWMEF QDSAKITERT AEWGLSAVKP DSGDDGISFK LSSEVERSKN
101: MSRRSSEEST SSESGAFPRV SQELKTALST LQQTFVVSDA TQPHCPIVYA SSGFFTMTGY SSKEIVGRNC RFLQGPDTDK NEVAKIRDCV KNGKSYCGRL
201: LNYKKDGTPF WNLLTVTPIK DDQGNTIKFI GMQVEVSKYT EGVNDKALRP NGLSKSLIRY DARQKEKALD SITEVVQTIR HRKSQVQESV SNDTMVKPDS
301: STTPTPGRQT RQSDEASKSF RTPGRVSTPT GSKLKSSNNR HEDLLRMEPE ELMLSTEVIG QRDSWDLSDR ERDIRQGIDL ATTLERIEKN FVISDPRLPD
401: NPIIFASDSF LELTEYSREE ILGRNCRFLQ GPETDQATVQ KIRDAIRDQR EITVQLINYT KSGKKFWNLF HLQPMRDQKG ELQYFIGVQL DGSDHVEPLQ
501: NRLSERTEMQ SSKLVKATAT NVDEAVRELP DANTRPEDLW AAHSKPVYPL PHNKESTSWK AIKKIQASGE TVGLHHFKPI KPLGSGDTGS VHLVELKGTG
601: ELYAMKAMEK TMMLNRNKAH RACIEREIIS LLDHPFLPTL YASFQTSTHV CLITDFCPGG ELFALLDRQP MKILTEDSAR FYAAEVVIGL EYLHCLGIVY
701: RDLKPENILL KKDGHIVLAD FDLSFMTTCT PQLIIPAAPS KRRRSKSQPL PTFVAEPSTQ SNSFVGTEEY IAPEIITGAG HTSAIDWWAL GILLYEMLYG
801: RTPFRGKNRQ KTFANILHKD LTFPSSIPVS LVGRQLINTL LNRDPSSRLG SKGGANEIKQ HAFFRGINWP LIRGMSPPPL DAPLSIIEKD PNAKDIKWED
901: DGVLVNSTDL DIDLF
See Also
Citation
If you find this resource useful please cite one of the following publications:

Hooper CM, Castleden I, Tanz SK, Aryamanesh, and Millar, AH (2017) SUBA4: the interactive data analysis centre for Arabidopsis subcellular protein locations Nucleic Acids Res. Jan 4;45(D1):D1064-D1074. doi: 10.1093/nar/gkw1041 (PubMed)

Hooper CM, Tanz SK, Castleden IR, Vacher MA, Small ID, Millar AH (2014) "SUBAcon: a consensus algorithm for unifying the subcellular localization data of the Arabidopsis proteome. Bioinformatics." 1;30(23):3356-64. (Bioinformatics) (PubMed)