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AT5G57160.1
Subcellular Consensus
(Prediction and Experimental)

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SUBAcon:
nucleus 1.000
ASURE: nucleus
What is SUBAcon?
What is ASURE?
SUBAcon computations
Experimental Localisations and PPI
FP MS/MS PPI
SUBAcon links
AGI-AGI relationships
Coexpression PPI
Description (TAIR10) protein_coding : DNA ligase IV
Curator
Summary (TAIR10)
Encodes the Arabidopsis orthologue of the yeast and mammalian DNA ligase IV. Involved in the repair of DNA damage but, unlike in yeast, not required for T-DNA integration. Interacts with the Arabidopsis homologue of XRCC4.
Computational
Description (TAIR10)
ATLIG4; FUNCTIONS IN: protein binding, DNA ligase (ATP) activity; INVOLVED IN: double-strand break repair, response to X-ray, response to DNA damage stimulus; LOCATED IN: intracellular; EXPRESSED IN: 23 plant structures; EXPRESSED DURING: 12 growth stages; CONTAINS InterPro DOMAIN/s: Nucleic acid-binding, OB-fold (InterPro:IPR012340), DNA ligase, N-terminal (InterPro:IPR012308), ATP dependent DNA ligase, central (InterPro:IPR012310), ATP dependent DNA ligase, C-terminal (InterPro:IPR012309), ATP-dependent DNA ligase, conserved site (InterPro:IPR016059), ATP-dependent DNA ligase (InterPro:IPR000977), BRCT (InterPro:IPR001357); BEST Arabidopsis thaliana protein match is: DNA ligase 1 (TAIR:AT1G08130.1); Has 7656 Blast hits to 6618 proteins in 1076 species: Archae - 317; Bacteria - 1869; Metazoa - 2250; Fungi - 907; Plants - 304; Viruses - 214; Other Eukaryotes - 1795 (source: NCBI BLink).
Protein Annotations
BioCyc:ARA:AT5G57160-MONOMERBioGrid:21066EC:6.5.1.1eggNOG:COG1793eggNOG:KOG0966EMBL:AB023042EMBL:AF233527
EMBL:CP002688EnsemblPlants:AT5G57160EnsemblPlants:AT5G57160.1entrez:835822Gene3D:1.10.3260.10Gene3D:2.40.50.140Gene3D:3.40.50.10190
GeneID:835822Genevisible:Q9LL84GO:GO:0003677GO:GO:0003910GO:GO:0003950GO:GO:0005524GO:GO:0005634
GO:GO:0005737GO:GO:0006273GO:GO:0006302GO:GO:0006303GO:GO:0006310GO:GO:0006974GO:GO:0009506
GO:GO:0010165GO:GO:0046872GO:GO:0048046GO:GO:0051103GO:GO:0071897Gramene:AT5G57160.1hmmpanther:PTHR10459
hmmpanther:PTHR10459:SF72HOGENOM:HOG000083793InParanoid:Q9LL84IntAct:Q9LL84InterPro:IPR000977InterPro:IPR001357InterPro:IPR012308
InterPro:IPR012309InterPro:IPR012310InterPro:IPR012340InterPro:IPR016059iPTMnet:Q9LL84KEGG:ath:AT5G57160KO:K10777
MINT:MINT-8071190ncoils:CoilOMA:IGEDHSRPaxDb:Q9LL84Pfam:PF01068Pfam:PF04675Pfam:PF04679
Pfam:PF12738Pfam:PF16589Pfam:Q9LL84Pfscan:PS50160Pfscan:PS50172PhylomeDB:Q9LL84PRIDE:Q9LL84
PRO:PR:Q9LL84PROSITE:PS00333PROSITE:PS00697PROSITE:PS50160PROSITE:PS50172ProteinModelPortal:Q9LL84Proteomes:UP000006548
RefSeq:NP_568851.2scanprosite:PS00333scanprosite:PS00697SMART:SM00292SMR:Q9LL84STRING:3702.AT5G57160.1SUPFAM:0050884
SUPFAM:SSF117018SUPFAM:SSF50249SUPFAM:SSF52113SUPFAM:SSF56091TAIR:AT5G57160tair10-symbols:ATLIG4tair10-symbols:LIG4
TIGRfam:TIGR00574TIGRFAMs:TIGR00574UniGene:At.49182UniGene:At.69713UniProt:Q9LL84
Coordinates (TAIR10) chr5:-:23155150..23161688
Molecular Weight (calculated) 137858.00 Da
IEP (calculated) 8.14
GRAVY (calculated) -0.62
Length 1219 amino acids
Sequence (TAIR10)
(BLAST)
0001: MTEEIKFSVL VSLFNWIQKS KTSSQKRSKF RKFLDTYCKP SDYFVAVRLI IPSLDRERGS YGLKESVLAT CLIDALGISR DAPDAVRLLN WRKGGTAKAG
0101: ANAGNFSLIA AEVLQRRQGM ASGGLTIKEL NDLLDRLASS ENRAEKTLVL STLIQKTNAQ EMKWVIRIIL KDLKLGMSEK SIFQEFHPDA EDLFNVTCDL
0201: KLVCEKLRDR HQRHKRQDIE VGKAVRPQLA MRIGDVNAAW KKLHGKDVVA ECKFDGDRIQ IHKNGTDIHY FSRNFLDHSE YAHAMSDLIV QNILVDKCIL
0301: DGEMLVWDTS LNRFAEFGSN QEIAKAAREG LDSHKQLCYV AFDVLYVGDT SVIHQSLKER HELLKKVVKP LKGRLEVLVP EGGLNVHRPS GEPSWSIVVH
0401: AAADVERFFK ETVENRDEGI VLKDLESKWE PGDRSGKWMK LKPEYIRAGA DLDVLIIGGY YGSGRRGGEV AQFLVALADR AEANVYPRRF MSFCRVGTGL
0501: SDDELNTVVS KLKPYFRKNE HPKKAPPSFY QVTNHSKERP DVWIDSPEKS IILSITSDIR TIRSEVFVAP YSLRFPRIDK VRYDKPWHEC LDVQAFVELV
0601: NSSNGTTQKQ KESESTQDNP KVNKSSKRGE KKNVSLVPSQ FIQTDVSDIK GKTSIFSNMI FYFVNVPRSH SLETFHKMVV ENGGKFSMNL NNSVTHCIAA
0701: ESSGIKYQAA KRQRDVIHFS WVLDCCSRNK MLPLLPKYFL HLTDASRTKL QDDIDEFSDS YYWDLDLEGL KQVLSNAKQS EDSKSIDYYK KKLCPEKRWS
0801: CLLSCCVYFY PYSQTLSTEE EALLGIMAKR LMLEVLMAGG KVSNNLAHAS HLVVLAMAEE PLDFTLVSKS FSEMEKRLLL KKRLHVVSSH WLEESLQREE
0901: KLCEDVYTLR PKYMEESDTE ESDKSEHDTT EVASQGSAQT KEPASSKIAI TSSRGRSNTR AVKRGRSSTN SLQRVQRRRG KQPSKISGDE TEESDASEEK
1001: VSTRLSDIAE ETDSFGEAQR NSSRGKCAKR GKSRVGQTQR VQRSRRGKKA AKIGGDESDE NDELDGNNNV SADAEEGNAA GRSVENEETR EPDIAKYTES
1101: QQRDNTVAVE EALQDSRNAK TEMDMKEKLQ IHEDPLQAML MKMFPIPSQK TTETSNRTTG EYRKANVSGE CESSEKRKLD AETDNTSVNA GAESDVVPPL
1201: VKKKKVSYRD VAGELLKDW
See Also
Citation
If you find this resource useful please cite one of the following publications:

Hooper CM, Castleden I, Tanz SK, Aryamanesh, and Millar, AH (2017) SUBA4: the interactive data analysis centre for Arabidopsis subcellular protein locations Nucleic Acids Res. Jan 4;45(D1):D1064-D1074. doi: 10.1093/nar/gkw1041 (PubMed)

Hooper CM, Tanz SK, Castleden IR, Vacher MA, Small ID, Millar AH (2014) "SUBAcon: a consensus algorithm for unifying the subcellular localization data of the Arabidopsis proteome. Bioinformatics." 1;30(23):3356-64. (Bioinformatics) (PubMed)