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AT5G53760.1
Subcellular Consensus
(Prediction and Experimental)
min: heatmap :max

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SUBAcon:
plasma membrane 1.000
ASURE: plasma membrane
What is SUBAcon?
Experimental Localisations and PPI
FP MS/MS PPI
SUBAcon links
AGI-AGI relationships
Coexpression PPI
Description (TAIR10) protein_coding : Seven transmembrane MLO family protein
Curator
Summary (TAIR10)
A member of a large family of seven-transmembrane domain proteins specific to plants, homologs of the barley mildew resistance locus o (MLO) protein. The Arabidopsis genome contains 15 genes encoding MLO proteins, with localization in plasma membrane. Phylogenetic analysis revealed four clades of closely-related AtMLO genes. ATMLO11 belongs to the clade I, with AtMLO4 and AtMLO14. The gene is expressed during early seedling growth (in primary root), in root tips and lateral root primordia, and in very young leaves, and in flowers and fruit abscission zone, as shown by GUS activity patterns. The expression of several phylogenetically closely-related AtMLO genes showed similar or overlapping tissue specificity and analogous responsiveness to external stimuli, suggesting functional redundancy, co-function, or antagonistic function(s).
Computational
Description (TAIR10)
MILDEW RESISTANCE LOCUS O 11 (MLO11); FUNCTIONS IN: calmodulin binding; INVOLVED IN: cell death, defense response; LOCATED IN: integral to membrane, plasma membrane; EXPRESSED IN: 25 plant structures; EXPRESSED DURING: 10 growth stages; CONTAINS InterPro DOMAIN/s: Mlo-related protein (InterPro:IPR004326); BEST Arabidopsis thaliana protein match is: Seven transmembrane MLO family protein (TAIR:AT1G26700.1); Has 1807 Blast hits to 1807 proteins in 277 species: Archae - 0; Bacteria - 0; Metazoa - 736; Fungi - 347; Plants - 385; Viruses - 0; Other Eukaryotes - 339 (source: NCBI BLink).
Protein Annotations
BioGrid:20701eggNOG:ENOG410IK25eggNOG:ENOG410XR5SEMBL:AB017066
EMBL:AF369572EMBL:AY057502EMBL:BT000434EMBL:BT002581
EMBL:CP002688EnsemblPlants:AT5G53760EnsemblPlants:AT5G53760.1EnsemblPlants:AT5G53760.2
entrez:835457ExpressionAtlas:Q9FI00GeneID:835457Genevisible:Q9FI00
GO:GO:0005886GO:GO:0006952GO:GO:0009607GO:GO:0016021
Gramene:AT5G53760.1Gramene:AT5G53760.2hmmpanther:PTHR31942hmmpanther:PTHR31942:SF15
HOGENOM:HOG000239166InParanoid:Q9FI00InterPro:IPR004326KEGG:ath:AT5G53760
KO:K08472OMA:YESFVSHPaxDb:Q9FI00Pfam:PF03094
Pfam:Q9FI00PhylomeDB:Q9FI00PRIDE:Q9FI00PRO:PR:Q9FI00
Proteomes:UP000006548RefSeq:NP_001032070.1RefSeq:NP_200187.1STRING:3702.AT5G53760.1
TAIR:AT5G53760tair10-symbols:ATMLO11tair10-symbols:MLO11TMHMM:TMhelix
UniGene:At.6980UniProt:B9DGT8UniProt:Q9FI00
Coordinates (TAIR10) chr5:+:21823055..21826289
Molecular Weight (calculated) 66353.40 Da
IEP (calculated) 9.21
GRAVY (calculated) -0.07
Length 573 amino acids
Sequence (TAIR10)
(BLAST)
001: MGEGEENGNE ADSNERSLAL SPTWSVAIVL TVFVVVSLIV ERSIYRLSTW LRKTKRKPMF AALEKMKEEL MLLGFISLLL TATSSTIANI CVPSSFYNDR
101: FLPCTRSEIQ EELESGSTVK RNLLTKSLFF NIFRRRLDVI KRTTCSEGHE PFVSYEGLEQ LHRFIFIMAV THVTYSCLTM LLAIVKIHSW RIWEDVARLD
201: RHDCLTAVAR EKIFRRQTTF VQYHTSAPLA KNRILIWVTC FFRQFGRSVD RSDYLTLRKG FIVNHHLTLK YDFHSYMIRS MEEEFQRIVG VSGPLWGFVV
301: AFMLFNIKGS NLYFWIAIIP VTLVLLVGAK LQHVIATLAL ENAGLTEYPS GVKLRPRDEL FWFNKPELLL SLIHFILFQN SFELASFFWF WWQFGYSSCF
401: LKNHYLVYFR LLLGFAGQFL CSYSTLPLYA LVTQMGTNYK AALIPQRIRE TIRGWGKATR RKRRHGLYGD DSTVRTETST IASLEEYDHQ VLDVTETSFE
501: QQRKQQEQGT TELELQPIQP RNDCVPNDTS SRVGTPLLRP WLSISSPTTT IELRSEPMET LSRSSSLPSE KRV
See Also
Citation
If you find this resource useful please cite one of the following publications:

Hooper CM, Castleden I, Tanz SK, Aryamanesh, and Millar, AH (2017) SUBA4: the interactive data analysis centre for Arabidopsis subcellular protein locations Nucleic Acids Res. Jan 4;45(D1):D1064-D1074. doi: 10.1093/nar/gkw1041 (PubMed)

Hooper CM, Tanz SK, Castleden IR, Vacher MA, Small ID, Millar AH (2014) "SUBAcon: a consensus algorithm for unifying the subcellular localization data of the Arabidopsis proteome. Bioinformatics." 1;30(23):3356-64. (Bioinformatics) (PubMed)