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AT5G50320.1
Subcellular Consensus
(Prediction and Experimental)

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SUBAcon:
nucleus 1.000
ASURE: nucleus
What is SUBAcon?
What is ASURE?
SUBAcon computations
Experimental Localisations and PPI
FP MS/MS PPI
SUBAcon links
AGI-AGI relationships
Coexpression PPI
no PPI data
Description (TAIR10) protein_coding : radical SAM domain-containing protein / GCN5-related N-acetyltransferase (GNAT) family protein
Curator
Summary (TAIR10)
A subunit of Elongator, a histone acetyl transferase complex, consisting of six subunits (ELP1?ELP6), that copurifies with the elongating RNAPII in yeast and humans. Three Arabidopsis thaliana genes, encoding homologs of the yeast Elongator subunits ELP1, ELP3 (histone acetyl transferase), and ELP4 are responsible for the narrow leaf phenotype in elongata mutants and for reduced root growth that results from a decreased cell division rate. Two lines with RNAi constructs directed against HAG3 grow normally and can produce root calli, but have defects in agrobacterium-mediated transformation.
Computational
Description (TAIR10)
ELONGATA 3 (ELO3); CONTAINS InterPro DOMAIN/s: GCN5-related N-acetyltransferase, C-terminal (InterPro:IPR022610), GCN5-related N-acetyltransferase (InterPro:IPR000182), Elongator protein 3/MiaB/NifB (InterPro:IPR006638), Histone acetyltransferase ELP3 (InterPro:IPR005910), Radical SAM (InterPro:IPR007197), Acyl-CoA N-acyltransferase (InterPro:IPR016181); Has 30201 Blast hits to 17322 proteins in 780 species: Archae - 12; Bacteria - 1396; Metazoa - 17338; Fungi - 3422; Plants - 5037; Viruses - 0; Other Eukaryotes - 2996 (source: NCBI BLink).
Protein Annotations
BioCyc:ARA:AT5G50320-MONOMERBioGrid:20344BRENDA:2.3.1.48EC:2.3.1.48eggNOG:COG1243eggNOG:KOG2535EMBL:AB012248
EMBL:AJ964958EMBL:AY054293EMBL:AY056323EMBL:AY133528EMBL:CP002688EnsemblPlants:AT5G50320EnsemblPlants:AT5G50320.1
entrez:835098Gene3D:3.40.630.30Gene3D:3.80.30.20GeneID:835098Genevisible:Q93ZR1GO:GO:0000123GO:GO:0002098
GO:GO:0004402GO:GO:0005634GO:GO:0005719GO:GO:0005829GO:GO:0006357GO:GO:0006368GO:GO:0008023
GO:GO:0008283GO:GO:0009294GO:GO:0009734GO:GO:0010084GO:GO:0010928GO:GO:0016573GO:GO:0033588
GO:GO:0035265GO:GO:0046872GO:GO:0051536GO:GO:2000025Gramene:AT5G50320.1hmmpanther:PTHR11135hmmpanther:PTHR11135:SF0
HOGENOM:HOG000227514InParanoid:Q93ZR1IntAct:Q93ZR1InterPro:IPR000182InterPro:IPR005910InterPro:IPR006638InterPro:IPR007197
InterPro:IPR016181InterPro:IPR023404InterPro:IPR032432iPTMnet:Q93ZR1KEGG:ath:AT5G50320KO:K07739OMA:GYKVVSH
PaxDb:Q93ZR1Pfam:PF00583Pfam:PF04055Pfam:PF16199Pfam:Q93ZR1Pfscan:PS51186PhylomeDB:Q93ZR1
PIRSF:PIRSF005669PRIDE:Q93ZR1PRO:PR:Q93ZR1PROSITE:PS51186ProteinModelPortal:Q93ZR1Proteomes:UP000006548RefSeq:NP_568725.1
SMART:SM00729STRING:3702.AT5G50320.1SUPFAM:SSF102114SUPFAM:SSF55729TAIR:AT5G50320tair10-symbols:AtELP3tair10-symbols:ELO3
tair10-symbols:ELP3tair10-symbols:HAC8tair10-symbols:HAG3TIGRfam:TIGR01211TIGRFAMs:TIGR01211UniGene:At.20657UniProt:Q93ZR1
Coordinates (TAIR10) chr5:-:20481200..20484811
Molecular Weight (calculated) 63698.00 Da
IEP (calculated) 8.83
GRAVY (calculated) -0.38
Length 565 amino acids
Sequence (TAIR10)
(BLAST)
001: MATAVVMNGE LKKQPRPGKG GYQGRGLTEE EARVRAISEI VSTMIERSHR NENVDLNAIK TAACRKYGLA RAPKLVEMIA ALPDSERETL LPKLRAKPVR
101: TASGIAVVAV MSKPHRCPHI ATTGNICVYC PGGPDSDFEY STQSYTGYEP TSMRAIRARY NPYVQARSRI DQLKRLGHSV DKVEFILMGG TFMSLPAEYR
201: DFFIRNLHDA LSGHTSANVE EAVAYSEHSA TKCIGMTIET RPDYCLGPHL RQMLIYGCTR LEIGVQSTYE DVARDTNRGH TVAAVADCFC LAKDAGFKVV
301: AHMMPDLPNV GVERDMESFK EFFESPSFRA DGLKIYPTLV IRGTGLYELW KTGRYRNYPP EQLVDIVARI LSMVPPWTRV YRVQRDIPMP LVTSGVEKGN
401: LRELALARMD DLGLKCRDVR TREAGIQDIH HKIKPEQVEL VRRDYTANEG WETFLSYEDT RQDILVGLLR LRKCGKNVTC PELMGKCSVV RELHVYGTAV
501: PVHGRDADKL QHQGYGTLLM EEAERIARRE HRSNKIGVIS GVGTRHYYRK LGYELEGPYM VKHLL
See Also
Citation
If you find this resource useful please cite one of the following publications:

Hooper CM, Castleden I, Tanz SK, Aryamanesh, and Millar, AH (2017) SUBA4: the interactive data analysis centre for Arabidopsis subcellular protein locations Nucleic Acids Res. Jan 4;45(D1):D1064-D1074. doi: 10.1093/nar/gkw1041 (PubMed)

Hooper CM, Tanz SK, Castleden IR, Vacher MA, Small ID, Millar AH (2014) "SUBAcon: a consensus algorithm for unifying the subcellular localization data of the Arabidopsis proteome. Bioinformatics." 1;30(23):3356-64. (Bioinformatics) (PubMed)