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AT5G50210.1
Subcellular Consensus
(Prediction and Experimental)
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SUBAcon:
plastid 1.000
What is SUBAcon?
Experimental Localisations and PPI
FP MS/MS PPI
  • PMID:31520498 (2020): mitochondrion
  • PMID:28865150 (2017): extracellular region plant-type cell wall
  • PMID:24124904 (2013): plastid
SUBAcon links
AGI-AGI relationships
Coexpression PPI
no PPI data
Description (TAIR10) protein_coding : quinolinate synthase
Curator
Summary (TAIR10)
Encodes an Fe-S binding protein with quinolinate synthase (QS) activity and cysteine desulfurase activator activity. The QS activity was demonstrated by functional complementation of corresponding E. coli mutants and complementation of embryo-lethal phenotypes of the QS homozygous null allele in Arabidopsis. The SufE domain of the protein also stimulates the cysteine desulfurase activity of CpNifS (AT1G08490) in vitro. This protein binds a (4Fe-Su)2+ cluster in its NadA domain and is localized in the chloroplast.
Computational
Description (TAIR10)
quinolinate synthase (QS); CONTAINS InterPro DOMAIN/s: Fe-S metabolism associated SufE (InterPro:IPR003808), Quinolinate synthetase A (InterPro:IPR003473); BEST Arabidopsis thaliana protein match is: sulfur E2 (TAIR:AT1G67810.1); Has 1807 Blast hits to 1807 proteins in 277 species: Archae - 0; Bacteria - 0; Metazoa - 736; Fungi - 347; Plants - 385; Viruses - 0; Other Eukaryotes - 339 (source: NCBI BLink).
Protein Annotations
BioCyc:ARA:AT5G50210-MONOMEREC:2.5.1.72eggNOG:COG0379eggNOG:COG2166
eggNOG:ENOG410IFDZEMBL:AB024031EMBL:AY035115EMBL:AY085553
EMBL:AY113860EMBL:CP002688EnsemblPlants:AT5G50210EnsemblPlants:AT5G50210.1
entrez:835086GeneID:835086Genevisible:Q9FGS4GO:GO:0008047
GO:GO:0008987GO:GO:0009060GO:GO:0009435GO:GO:0009507
GO:GO:0016226GO:GO:0016740GO:GO:0019805GO:GO:0042803
GO:GO:0043085GO:GO:0046872GO:GO:0051176GO:GO:0051539
Gramene:AT5G50210.1gramene_pathway:2.5.1.72gramene_pathway:PYRIDNUCSYN-PWYgramene_plant_reactome:1119384
gramene_plant_reactome:6874084hmmpanther:PTHR30573hmmpanther:PTHR30573:SF3HOGENOM:HOG000265746
InParanoid:Q9FGS4InterPro:IPR003473InterPro:IPR003808KEGG:ath:AT5G50210
KO:K03517OMA:VYRMSDEPaxDb:Q9FGS4Pfam:PF02445
Pfam:PF02657Pfam:Q9FGS4PhylomeDB:Q9FGS4PRIDE:Q9FGS4
PRO:PR:Q9FGS4ProteinModelPortal:Q9FGS4Proteomes:UP000006548RefSeq:NP_199832.1
SMR:Q9FGS4STRING:3702.AT5G50210.1SUPFAM:0050763SUPFAM:SSF82649
SwissPalm:Q9FGS4TAIR:AT5G50210tair10-symbols:OLD5tair10-symbols:QS
tair10-symbols:SUFE3UniGene:At.7913UniPathway:UPA00253UniProt:Q9FGS4
Coordinates (TAIR10) chr5:+:20442803..20445706
Molecular Weight (calculated) 78938.20 Da
IEP (calculated) 6.87
GRAVY (calculated) -0.06
Length 718 amino acids
Sequence (TAIR10)
(BLAST)
001: MALALSVAPT SSSLSSLLSR TPNPSPNFRT THLNFGSQRR IYTINPLLRS FKCLQSSSRD VNASPFSISA IASSSSSSQT TELVPYKLQR LVKEFKSLTE
101: PIDRLKWVLH YASLLPQMPE SSKTESNRVM GCTARVWLDA ELGQDGKMRF CADSDSDVSK GMCSCLIQVL DEASPVEVME LKTEDLAELN VGLLGGERSR
201: VNTWYNVLVS MQKKTRRLVA EREGKVPSFE PFPSLVLTAH GIEAKGSFAQ AQAKYLFPEE SRVEELVNVL KEKKIGVVAH FYMDPEVQGV LTAAQKHWPH
301: ISISDSLVMA DSAVTMAKAG CQFITVLGVD FMSENVRAIL DQAGFEKVGV YRMSDETIGC SLADAASAPA YLNYLEAASR SPPSLHVVYI NTSLETKAFA
401: HELVPTITCT SSNVVQTILQ AFAQMPELTV WYGPDSYMGA NIVKLFQQMT LMTNEEIANI HPKHSLDSIK SLLPRLHYFQ EGTCIVHHLF GHEVVERIKY
501: MYCDAFLTAH LEVPGEMFSL AMEAKKREMG VVGSTQNILD FIKQKVQEAV DRNVDDHLQF VLGTESGMVT SIVAVIRSLL GSSANSKLKV EVVFPVSSDS
601: MTKTSSDSSN SIKVGDVALP VVPGVAGGEG CSIHGGCASC PYMKMNSLSS LLKVCHKLPD LENVYGGFIA ERFKRQTPQG KLIADVGCEP ILHMRHFQAN
701: KELPDKLVHQ VLSCESKR
See Also
Citation
If you find this resource useful please cite one of the following publications:

Hooper CM, Castleden I, Tanz SK, Aryamanesh, and Millar, AH (2017) SUBA4: the interactive data analysis centre for Arabidopsis subcellular protein locations Nucleic Acids Res. Jan 4;45(D1):D1064-D1074. doi: 10.1093/nar/gkw1041 (PubMed)

Hooper CM, Tanz SK, Castleden IR, Vacher MA, Small ID, Millar AH (2014) "SUBAcon: a consensus algorithm for unifying the subcellular localization data of the Arabidopsis proteome. Bioinformatics." 1;30(23):3356-64. (Bioinformatics) (PubMed)