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AT5G48100.1
Subcellular Consensus
(Prediction and Experimental)
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SUBAcon:
extracellular 1.000
What is SUBAcon?
Experimental Localisations and PPI
FP MS/MS PPI
SUBAcon links
AGI-AGI relationships
Coexpression PPI
no PPI data
Description (TAIR10) protein_coding : Laccase/Diphenol oxidase family protein
Curator
Summary (TAIR10)
Encodes a protein that is similar to laccase-like polyphenol oxidases. Involved in lignin and flavonoids biosynthesis. It has four conserved copper binding domains. Expressed in developing testa, where it colocalizes with the flavonoid end products proanthocyanidins and flavonols. Mutant plants exhibited a delay in developmentally determined browning of the testa, characterized by the pale brown color of seed coat. The tt10 mutant seeds accumulate more epicatechin monomers and more soluble proanthocyanidins than wild-type seeds. Flavonol composition was also affected in tt10 seeds, which exhibited a higher ratio of quercetin rhamnoside monomers versus dimers than wild-type seeds.
Computational
Description (TAIR10)
TRANSPARENT TESTA 10 (TT10); FUNCTIONS IN: copper ion binding, laccase activity; INVOLVED IN: lignin biosynthetic process, response to copper ion, flavonoid biosynthetic process; LOCATED IN: endomembrane system, apoplast; EXPRESSED IN: 8 plant structures; EXPRESSED DURING: L mature pollen stage, M germinated pollen stage, 4 anthesis, seedling growth, seed development stages; CONTAINS InterPro DOMAIN/s: Multicopper oxidase, type 3 (InterPro:IPR011707), Laccase (InterPro:IPR017761), Multicopper oxidase, type 2 (InterPro:IPR011706), Cupredoxin (InterPro:IPR008972), Multicopper oxidase, copper-binding site (InterPro:IPR002355), Multicopper oxidase, type 1 (InterPro:IPR001117); BEST Arabidopsis thaliana protein match is: laccase 14 (TAIR:AT5G09360.1); Has 10402 Blast hits to 8649 proteins in 1516 species: Archae - 36; Bacteria - 4416; Metazoa - 511; Fungi - 3532; Plants - 1551; Viruses - 0; Other Eukaryotes - 356 (source: NCBI BLink).
Protein Annotations
BioCyc:ARA:AT5G48100-MONOMEREC:1.10.3.2eggNOG:COG2132eggNOG:KOG1263
EMBL:AB017064EMBL:BT002919EMBL:BT005152EMBL:CP002688
EnsemblPlants:AT5G48100EnsemblPlants:AT5G48100.1entrez:834862Gene3D:2.60.40.420
GeneID:834862Genevisible:Q84J37GO:GO:0005507GO:GO:0009809
GO:GO:0010023GO:GO:0016722GO:GO:0046274GO:GO:0046688
GO:GO:0048046GO:GO:0052716Gramene:AT5G48100.1hmmpanther:PTHR11709
hmmpanther:PTHR11709:SF94HOGENOM:HOG000241916InParanoid:Q84J37InterPro:IPR001117
InterPro:IPR002355InterPro:IPR008972InterPro:IPR011706InterPro:IPR011707
InterPro:IPR017761InterPro:IPR033138KEGG:ath:AT5G48100KO:K05909
OMA:ATYITISPaxDb:Q84J37Pfam:PF00394Pfam:PF07731
Pfam:PF07732Pfam:Q84J37PhylomeDB:Q84J37PRIDE:Q84J37
PRO:PR:Q84J37PROSITE:PS00079PROSITE:PS00080ProteinModelPortal:Q84J37
Proteomes:UP000006548RefSeq:NP_199621.2scanprosite:PS00079scanprosite:PS00080
SMR:Q84J37STRING:3702.AT5G48100.1SUPFAM:SSF49503TAIR:AT5G48100
tair10-symbols:ATLAC15tair10-symbols:LAC15tair10-symbols:TT10TIGRfam:TIGR03389
TIGRFAMs:TIGR03389UniGene:At.9463UniProt:Q84J37
Coordinates (TAIR10) chr5:-:19489530..19492582
Molecular Weight (calculated) 63997.50 Da
IEP (calculated) 7.51
GRAVY (calculated) -0.16
Length 565 amino acids
Sequence (TAIR10)
(BLAST)
001: MSHSFFNLFL ISLFLYNNCI AHHYTFTVRE VPYTKLCSTK AILTVNSQFP GPIIKVHKGD TIYVNVQNRA SENITMHWHG VEQPRNPWSD GPEYITQCPI
101: RPGSDFLYKV IFSIEDTTVW WHAHSSWTRA TVHGLIFVYP RPPQILPFPK ADHEVPIILG EWWKRDVREV VEEFVRTGGA PNVSDALTIN GHPGFLYPCS
201: KSDTFHLTVE KGKTYRIRMV NAAMNLPLFF AIANHSLTVV SADGHYIKPI KATYITISPG ETLDMLLHAD QDPERTYYMA ARAYQSGNID FNNSTTIGIL
301: SYTSSCKAKT SSFSGYYPTL PFYNDTSAAF GFFTKIKCLF SGQVPVQISR RIITTVSINL RMCPQNSCEG PNGSRLAASM NNISFVTPSH VDILKAYYYH
401: IKGVYGTRFP EFPPLIFNFT AENQPLFLET PRLATEVKVI EFGQVVELVI QGTSLVGGGL DHPMHLHGFS FYVVGVGFGN YNISEEDPSS RYNLYDPPYK
501: NTMTVPRNGW IAIRFVADNP GVWFMHCHLD RHQTWGMNVV FIVKNGREPN QQILPPPDDL PPCYE
See Also
Citation
If you find this resource useful please cite one of the following publications:

Hooper CM, Castleden I, Tanz SK, Aryamanesh, and Millar, AH (2017) SUBA4: the interactive data analysis centre for Arabidopsis subcellular protein locations Nucleic Acids Res. Jan 4;45(D1):D1064-D1074. doi: 10.1093/nar/gkw1041 (PubMed)

Hooper CM, Tanz SK, Castleden IR, Vacher MA, Small ID, Millar AH (2014) "SUBAcon: a consensus algorithm for unifying the subcellular localization data of the Arabidopsis proteome. Bioinformatics." 1;30(23):3356-64. (Bioinformatics) (PubMed)