AT5G48000.1
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Subcellular Consensus
(Prediction and Experimental) min:  :max.
SUBAcon:endoplasmic reticulum 1.000 What is SUBAcon? |
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| Experimental Localisations and PPI |
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SUBAcon links
AGI-AGI relationships |
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| Description (TAIR10) | protein_coding : cytochrome P450, family 708, subfamily A, polypeptide 2 | ||||||||||||||||||||||||||||||||||||||||||||||||||||
| Curator Summary (TAIR10) |
Encodes a member of the CYP708A family of cytochrome P450 enzymes. THAH appears to add a hydroxyl group to the triterpene thalianol. thah1 mutants have an elevated accumulation of thalianol. thah1-1 mutants have longer roots than wild type plants. Thalian-diol and desaturated thalian-diol are lost from the root extracts of thah1-1 mutants. Overexpression of the sequence from At5g48000.1 rescues the thah1-1 mutant phenotype (Field 2008); it is unknown whether the shorter sequences associated with other gene models would provide functional complementation. | ||||||||||||||||||||||||||||||||||||||||||||||||||||
| Computational Description (TAIR10) |
cytochrome P450, family 708, subfamily A, polypeptide 2 (CYP708A2); FUNCTIONS IN: thalianol hydroxylase activity, oxygen binding; INVOLVED IN: thalianol metabolic process, root development; LOCATED IN: endoplasmic reticulum; EXPRESSED IN: hypocotyl, root, callus; CONTAINS InterPro DOMAIN/s: Cytochrome P450 (InterPro:IPR001128), Cytochrome P450, E-class, group IV (InterPro:IPR002403), Cytochrome P450, conserved site (InterPro:IPR017972); BEST Arabidopsis thaliana protein match is: cytochrome P450, family 708, subfamily A, polypeptide 3 (TAIR:AT1G78490.1); Has 28765 Blast hits to 28695 proteins in 1599 species: Archae - 49; Bacteria - 5026; Metazoa - 10250; Fungi - 5008; Plants - 7191; Viruses - 6; Other Eukaryotes - 1235 (source: NCBI BLink). | ||||||||||||||||||||||||||||||||||||||||||||||||||||
| Protein Annotations |
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| Coordinates (TAIR10) | chr5:-:19444313..19447790 | ||||||||||||||||||||||||||||||||||||||||||||||||||||
| Molecular Weight (calculated) | 58880.80 Da | ||||||||||||||||||||||||||||||||||||||||||||||||||||
| IEP (calculated) | 9.51 | ||||||||||||||||||||||||||||||||||||||||||||||||||||
| GRAVY (calculated) | -0.08 | ||||||||||||||||||||||||||||||||||||||||||||||||||||
| Length | 518 amino acids | ||||||||||||||||||||||||||||||||||||||||||||||||||||
| Sequence (TAIR10) (BLAST) |
001: MDRRGKYWAG PMWIGLSMCG SGSDTILECR LRLFKLQRQN QMSFVWSAAV WVIAVAAVVI SKWLYRWSNP KCNGKLPPGS MGLPIIGETC DFFEPHGLYE 101: ISPFVKKRML KYGPLFRTNI FGSNTVVLTE PDIIFEVFRQ ENKSFVFSYP EAFVKPFGKE NVFLKHGNIH KHVKQISLQH LGSEALKKKM IGEIDRVTYE 201: HLRSKANQGS FDAKEAVESV IMAHLTPKII SNLKPETQAT LVDNIMALGS EWFQSPLKLT TLISIYKVFI ARRYALQVIK DVFTRRKASR EMCGDFLDTM 301: VEEGEKEDVI FNEESAINLI FAILVVAKES TSSVTSLAIK FLAENHKALA ELKREHAAIL QNRNGKGAGV SWEEYRHQMT FTNMVINETL RMANMAPIMY 401: RKAVNDVEIK GYTIPAGWIV AVIPPAVHFN DAIYENPLEF NPWRWEGKEL RSGSKTFMVF GGGVRQCVGA EFARLQISIF IHHLVTTYDF SLAQESEFIR 501: APLPYFPKGL PIKISQSL |
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| See Also |
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Citation
If you find this resource useful please cite one of the following publications:
Hooper CM, Castleden I, Tanz SK, Aryamanesh, and Millar, AH (2017) SUBA4: the interactive data analysis centre for Arabidopsis subcellular protein locations Nucleic Acids Res. Jan 4;45(D1):D1064-D1074. doi: 10.1093/nar/gkw1041 (PubMed)
Hooper CM, Tanz SK, Castleden IR, Vacher MA, Small ID, Millar AH (2014) "SUBAcon: a consensus algorithm for unifying the subcellular localization data of the Arabidopsis proteome. Bioinformatics." 1;30(23):3356-64. (Bioinformatics) (PubMed)