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AT5G46860.1
Subcellular Consensus
(Prediction and Experimental)

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SUBAcon:
vacuole 1.000
ASURE: vacuole
What is SUBAcon?
What is ASURE?
SUBAcon computations
Experimental Localisations and PPI
FP MS/MS PPI
  • PMID:24556575 (2014): plant-type vacuole
  • PMID:17602189 (2007): plant-type vacuole plant-type vacuole membrane
  • PMID:17259264 (2007): Golgi trans-Golgi network
  • PMID:17259264 (2007): plant-type vacuole plant-type vacuole membrane
  • PMID:16672254 (2006): plant-type vacuole
  • PMID:16262709 (2005): plant-type vacuole
  • PMID:15546360 (2004): endoplasmic reticulum
  • PMID:15342965 (2004): plant-type vacuole
  • PMID:12354913 (2002): plant-type vacuole
  • PMID:12081650 (2002): plant-type vacuole
  • PMID:25900983 (2015): Golgi trans-Golgi network
  • PMID:25900983 (2015): Golgi trans-Golgi network early endosome
  • PMID:25900983 (2015): Golgi trans-Golgi network multivesicular body
  • PMID:25641898 (2015): plasma membrane
  • PMID:22215637 (2012): plasma membrane
  • PMID:15539469 (2004): plant-type vacuole
  • PMID:14760709 (2004): plant-type vacuole
SUBAcon links
AGI-AGI relationships
Coexpression PPI
Description (TAIR10) protein_coding : Syntaxin/t-SNARE family protein
Curator
Summary (TAIR10)
Syntaxin-related protein required for vacuolar assembly. A member of t-SNARE superfamily, homologous to yest Vam3p. Localized in the vacuolar membranes. The protein has a heptad repeat structure (residues164-220) in which hydrophobic amino acid residues appear at seven amino acid intervals. Such regions have a high potential to form an amphiphilic a-helix, intriguing for the intermolecular interactions by forming coiled-coil structure. AtVam3p has a highly hydrophobic segment at its C terminus thus implicating it to be a membrane protein while the rest of the sequence is hydrophilic.
Computational
Description (TAIR10)
VACUOLAR MORPHOLOGY 3 (VAM3); FUNCTIONS IN: SNAP receptor activity; INVOLVED IN: in 7 processes; LOCATED IN: late endosome, trans-Golgi network transport vesicle, plant-type vacuole membrane, vacuole, plant-type vacuole; EXPRESSED IN: 24 plant structures; EXPRESSED DURING: 15 growth stages; CONTAINS InterPro DOMAIN/s: Target SNARE coiled-coil domain (InterPro:IPR000727), t-SNARE (InterPro:IPR010989), Syntaxin/epimorphin, conserved site (InterPro:IPR006012), Syntaxin, N-terminal (InterPro:IPR006011); BEST Arabidopsis thaliana protein match is: syntaxin of plants 23 (TAIR:AT4G17730.2); Has 30201 Blast hits to 17322 proteins in 780 species: Archae - 12; Bacteria - 1396; Metazoa - 17338; Fungi - 3422; Plants - 5037; Viruses - 0; Other Eukaryotes - 2996 (source: NCBI BLink).
Protein Annotations
BioGrid:19978eggNOG:COG5325eggNOG:KOG0811EMBL:AB022221EMBL:AF385695EMBL:AY072015EMBL:AY085121
EMBL:AY133666EMBL:CP002688EMBL:U88045EnsemblPlants:AT5G46860EnsemblPlants:AT5G46860.1entrez:834730GeneID:834730
Genevisible:P93654GO:GO:0000149GO:GO:0000325GO:GO:0005773GO:GO:0006886GO:GO:0006906GO:GO:0009660
GO:GO:0009705GO:GO:0009959GO:GO:0010118GO:GO:0016021GO:GO:0031201GO:GO:0031902GO:GO:0048278
Gramene:AT5G46860.1hmmpanther:PTHR19957hmmpanther:PTHR19957:SF120HOGENOM:HOG000188453InParanoid:P93654IntAct:P93654InterPro:IPR000727
InterPro:IPR006011InterPro:IPR006012InterPro:IPR010989iPTMnet:P93654KEGG:ath:AT5G46860KO:K08488OMA:KTRAHIT
PaxDb:P93654Pfam:P93654Pfam:PF05739Pfam:PF14523Pfscan:PS50192PhylomeDB:P93654PRIDE:P93654
PRO:PR:P93654PROSITE:PS00914PROSITE:PS50192ProteinModelPortal:P93654Proteomes:UP000006548RefSeq:NP_568671.1scanprosite:PS00914
SMART:SM00397SMART:SM00503SMR:P93654STRING:3702.AT5G46860.1SUPFAM:SSF47661TAIR:AT5G46860tair10-symbols:ATSYP22
tair10-symbols:ATVAM3tair10-symbols:SGR3tair10-symbols:SYP22tair10-symbols:VAM3TMHMM:TMhelixUniGene:At.22922UniGene:At.50510
UniProt:P93654
Coordinates (TAIR10) chr5:-:19012342..19013795
Molecular Weight (calculated) 29483.00 Da
IEP (calculated) 6.37
GRAVY (calculated) -0.37
Length 268 amino acids
Sequence (TAIR10)
(BLAST)
001: MSFQDLESGR GRSTRKFNGG RQDSTQAVAS GIFQINTGVS TFQRLVNTLG TPKDTPELRE KLHKTRLHIG QLVKDTSAKL KEASETDHQS GVNPSKKIAD
101: AKLARDFQAV LKEFQKAQQT AAERETTYTP FVPQSALPSS YTAGEVDKVP EQRAQLQESK RQELVLLDNE IAFNEAVIEE REQGIQEIHQ QIGEVNEIFK
201: DLAVLVNDQG VMIDDIGTHI DNSRAATSQG KSQLVQAAKT QKSNSSLTCL LLVIFGIVLL IVIIVLAA
See Also
Citation
If you find this resource useful please cite one of the following publications:

Hooper CM, Castleden I, Tanz SK, Aryamanesh, and Millar, AH (2017) SUBA4: the interactive data analysis centre for Arabidopsis subcellular protein locations Nucleic Acids Res. Jan 4;45(D1):D1064-D1074. doi: 10.1093/nar/gkw1041 (PubMed)

Hooper CM, Tanz SK, Castleden IR, Vacher MA, Small ID, Millar AH (2014) "SUBAcon: a consensus algorithm for unifying the subcellular localization data of the Arabidopsis proteome. Bioinformatics." 1;30(23):3356-64. (Bioinformatics) (PubMed)