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AT5G46330.1
Subcellular Consensus
(Prediction and Experimental)

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SUBAcon:
plasma membrane 1.000
What is SUBAcon?
What is ASURE?
SUBAcon computations
Predictors External Curations
SwissProt : endoplasmic reticulum 16381842
SwissProt : plasma membrane 16381842
TAIR : plasma membrane 17317660
Experimental Localisations and PPI
FP MS/MS PPI
SUBAcon links
AGI-AGI relationships
Coexpression PPI
Description (TAIR10) protein_coding : Leucine-rich receptor-like protein kinase family protein
Curator
Summary (TAIR10)
Encodes a leucine-rich repeat serine/threonine protein kinase that is expressed ubiquitously. FLS2 is involved in MAP kinase signalling relay involved in innate immunity. Essential in the perception of flagellin, a potent elicitor of the defense response. FLS2 is directed for degradation by the bacterial ubiquitin ligase AvrPtoB.
Computational
Description (TAIR10)
FLAGELLIN-SENSITIVE 2 (FLS2); FUNCTIONS IN: protein serine/threonine kinase activity, transmembrane receptor protein serine/threonine kinase activity, kinase activity, ATP binding; INVOLVED IN: in 6 processes; LOCATED IN: plasma membrane, membrane; EXPRESSED IN: 21 plant structures; EXPRESSED DURING: 10 growth stages; CONTAINS InterPro DOMAIN/s: Serine/threonine-protein kinase domain (InterPro:IPR002290), Leucine-rich repeat-containing N-terminal domain, type 2 (InterPro:IPR013210), Leucine-rich repeat (InterPro:IPR001611), Serine/threonine-protein kinase-like domain (InterPro:IPR017442), Serine/threonine-protein kinase, active site (InterPro:IPR008271), Protein kinase-like domain (InterPro:IPR011009), Protein kinase, catalytic domain (InterPro:IPR000719), Leucine-rich repeat, typical subtype (InterPro:IPR003591), Tyrosine-protein kinase, catalytic domain (InterPro:IPR020635); BEST Arabidopsis thaliana protein match is: Leucine-rich repeat transmembrane protein kinase (TAIR:AT4G20140.1); Has 1807 Blast hits to 1807 proteins in 277 species: Archae - 0; Bacteria - 0; Metazoa - 736; Fungi - 347; Plants - 385; Viruses - 0; Other Eukaryotes - 339 (source: NCBI BLink).
Protein Annotations
BioCyc:ARA:AT5G46330-MONOMERBioGrid:19925DIP:DIP-46004NDNASU:834676EC:2.7.11.1eggNOG:COG0515eggNOG:COG4886
eggNOG:ENOG410IH3GEMBL:AB010698EMBL:AK226709EMBL:BT003880EMBL:CP002688EnsemblPlants:AT5G46330EnsemblPlants:AT5G46330.1
entrez:834676ExpressionAtlas:Q9FL28Gene3D:2.60.120.200Gene3D:3.80.10.10GeneID:834676Genevisible:Q9FL28GO:GO:0004675
GO:GO:0005524GO:GO:0005768GO:GO:0005886GO:GO:0006898GO:GO:0007178GO:GO:0010008GO:GO:0010359
GO:GO:0016020GO:GO:0016021GO:GO:0016045GO:GO:0042742GO:GO:0052544Gramene:AT5G46330.1hmmpanther:PTHR27000
hmmpanther:PTHR27000:SF16HOGENOM:HOG000116551InParanoid:Q9FL28IntAct:Q9FL28InterPro:IPR000719InterPro:IPR001611InterPro:IPR003591
InterPro:IPR008271InterPro:IPR011009InterPro:IPR013210InterPro:IPR013320InterPro:IPR032675iPTMnet:Q9FL28KEGG:ath:AT5G46330
KO:K13420OMA:PENIIGAPaxDb:Q9FL28PDB:4MN8PDB:4MNAPDBsum:4MN8PDBsum:4MNA
Pfam:PF00069Pfam:PF00560Pfam:PF08263Pfam:PF13855Pfam:Q9FL28Pfscan:PS50011PhylomeDB:Q9FL28
PRIDE:Q9FL28PRO:PR:Q9FL28PROSITE:PS00108PROSITE:PS50011ProteinModelPortal:Q9FL28Proteomes:UP000006548RefSeq:NP_199445.1
scanprosite:PS00108SMART:SM00220SMART:SM00369SMR:Q9FL28STRING:3702.AT5G46330.1SUPFAM:SSF52047SUPFAM:SSF52058
SUPFAM:SSF56112SwissPalm:Q9FL28TAIR:AT5G46330tair10-symbols:FLS2TMHMM:TMhelixUniGene:At.29960UniProt:C0LGU8
UniProt:Q9FL28
Coordinates (TAIR10) chr5:+:18791802..18795407
Molecular Weight (calculated) 128832.00 Da
IEP (calculated) 5.57
GRAVY (calculated) -0.02
Length 1173 amino acids
Sequence (TAIR10)
(BLAST)
0001: MKLLSKTFLI LTLTFFFFGI ALAKQSFEPE IEALKSFKNG ISNDPLGVLS DWTIIGSLRH CNWTGITCDS TGHVVSVSLL EKQLEGVLSP AIANLTYLQV
0101: LDLTSNSFTG KIPAEIGKLT ELNQLILYLN YFSGSIPSGI WELKNIFYLD LRNNLLSGDV PEEICKTSSL VLIGFDYNNL TGKIPECLGD LVHLQMFVAA
0201: GNHLTGSIPV SIGTLANLTD LDLSGNQLTG KIPRDFGNLL NLQSLVLTEN LLEGDIPAEI GNCSSLVQLE LYDNQLTGKI PAELGNLVQL QALRIYKNKL
0301: TSSIPSSLFR LTQLTHLGLS ENHLVGPISE EIGFLESLEV LTLHSNNFTG EFPQSITNLR NLTVLTVGFN NISGELPADL GLLTNLRNLS AHDNLLTGPI
0401: PSSISNCTGL KLLDLSHNQM TGEIPRGFGR MNLTFISIGR NHFTGEIPDD IFNCSNLETL SVADNNLTGT LKPLIGKLQK LRILQVSYNS LTGPIPREIG
0501: NLKDLNILYL HSNGFTGRIP REMSNLTLLQ GLRMYSNDLE GPIPEEMFDM KLLSVLDLSN NKFSGQIPAL FSKLESLTYL SLQGNKFNGS IPASLKSLSL
0601: LNTFDISDNL LTGTIPGELL ASLKNMQLYL NFSNNLLTGT IPKELGKLEM VQEIDLSNNL FSGSIPRSLQ ACKNVFTLDF SQNNLSGHIP DEVFQGMDMI
0701: ISLNLSRNSF SGEIPQSFGN MTHLVSLDLS SNNLTGEIPE SLANLSTLKH LKLASNNLKG HVPESGVFKN INASDLMGNT DLCGSKKPLK PCTIKQKSSH
0801: FSKRTRVILI ILGSAAALLL VLLLVLILTC CKKKEKKIEN SSESSLPDLD SALKLKRFEP KELEQATDSF NSANIIGSSS LSTVYKGQLE DGTVIAVKVL
0901: NLKEFSAESD KWFYTEAKTL SQLKHRNLVK ILGFAWESGK TKALVLPFME NGNLEDTIHG SAAPIGSLLE KIDLCVHIAS GIDYLHSGYG FPIVHCDLKP
1001: ANILLDSDRV AHVSDFGTAR ILGFREDGST TASTSAFEGT IGYLAPEFAY MRKVTTKADV FSFGIIMMEL MTKQRPTSLN DEDSQDMTLR QLVEKSIGNG
1101: RKGMVRVLDM ELGDSIVSLK QEEAIEDFLK LCLFCTSSRP EDRPDMNEIL THLMKLRGKA NSFREDRNED REV
See Also
Citation
If you find this resource useful please cite one of the following publications:

Hooper CM, Castleden I, Tanz SK, Aryamanesh, and Millar, AH (2017) SUBA4: the interactive data analysis centre for Arabidopsis subcellular protein locations Nucleic Acids Res. Jan 4;45(D1):D1064-D1074. doi: 10.1093/nar/gkw1041 (PubMed)

Hooper CM, Tanz SK, Castleden IR, Vacher MA, Small ID, Millar AH (2014) "SUBAcon: a consensus algorithm for unifying the subcellular localization data of the Arabidopsis proteome. Bioinformatics." 1;30(23):3356-64. (Bioinformatics) (PubMed)