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AT5G46240.1
Subcellular Consensus
(Prediction and Experimental)
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SUBAcon:
plasma membrane 1.000
ASURE: plasma membrane
What is SUBAcon?
Experimental Localisations and PPI
FP MS/MS PPI
  • PMID:9707551 (1998): plasma membrane
  • PMID:9368418 (1997): plasma membrane
  • PMID:14731259 (2004): plasma membrane
SUBAcon links
AGI-AGI relationships
Coexpression PPI
Description (TAIR10) protein_coding : potassium channel in Arabidopsis thaliana 1
Curator
Summary (TAIR10)
Encodes a potassium channel protein (KAT1). ABA triggers KAT1 endocytosis both in epidermal cells as well as guard cells. Upon removal of ABA, KAT1 is recycled back to the plasma membrane. KAT1 is localized within 0.5?0.6 μm diameter microdomains at the plasma membrane surface. KAT1 belongs to the Shaker family K+ channel. This family includes five groups based on phylogenetic analysis (FEBS Letters (2007) 581: 2357): I (inward rectifying channel): AKT1 (AT2G26650), AKT5 (AT4G32500) and SPIK (also known as AKT6, AT2G25600); II (inward rectifying channel): KAT1 (AT5G46240) and KAT2 (AT4G18290); III (weakly inward rectifying channel): AKT2 (AT4G22200); IV (regulatory subunit involved in inwardly rectifying conductance formation): KAT3 (also known as AtKC1, AT4G32650); V (outward rectifying channel): SKOR (AT3G02850) and GORK (AT5G37500).
Computational
Description (TAIR10)
potassium channel in Arabidopsis thaliana 1 (KAT1); CONTAINS InterPro DOMAIN/s: Cyclic nucleotide-binding (InterPro:IPR000595), Cyclic nucleotide-binding-like (InterPro:IPR018490), Ion transport (InterPro:IPR005821), Potassium channel, voltage-dependent, EAG/ELK/ERG (InterPro:IPR003938), RmlC-like jelly roll fold (InterPro:IPR014710), Protein of unknown function DUF3354 (InterPro:IPR021789); BEST Arabidopsis thaliana protein match is: potassium channel in Arabidopsis thaliana 2 (TAIR:AT4G18290.1); Has 1807 Blast hits to 1807 proteins in 277 species: Archae - 0; Bacteria - 0; Metazoa - 736; Fungi - 347; Plants - 385; Viruses - 0; Other Eukaryotes - 339 (source: NCBI BLink).
Protein Annotations
eggNOG:ENOG410XPSEeggNOG:KOG0498EMBL:AK176505EMBL:AK220637
EMBL:BT046198EnsemblPlants:AT5G46240EnsemblPlants:AT5G46240.1entrez:834666
ExpressionAtlas:Q67YG3Gene3D:2.60.120.10GeneID:834666GO:GO:0005249
GO:GO:0016021GO:GO:0042802Gramene:AT5G46240.1hmmpanther:PTHR10217
hmmpanther:PTHR10217:SF520InterPro:IPR000595InterPro:IPR003938InterPro:IPR005821
InterPro:IPR014710InterPro:IPR018490InterPro:IPR021789KEGG:ath:AT5G46240
OMA:CVEEYNIPfam:PF00027Pfam:PF00520Pfam:PF11834
Pfam:Q39128Pfscan:PS50042Pfscan:PS51490PhylomeDB:Q67YG3
PRINTS:PR01463PROSITE:PS50042PROSITE:PS51490RefSeq:NP_199436.1
SMART:SM00100SMR:Q67YG3STRING:3702.AT5G46240.1SUPFAM:SSF51206
SUPFAM:SSF81324TAIR:AT5G46240tair10-symbols:KAT1TMHMM:TMhelix
UniGene:At.305UniProt:Q39128UniProt:Q67YG3
Coordinates (TAIR10) chr5:-:18743652..18746561
Molecular Weight (calculated) 78274.80 Da
IEP (calculated) 7.75
GRAVY (calculated) -0.17
Length 677 amino acids
Sequence (TAIR10)
(BLAST)
001: MSISWTRNFF ERFCVEEYNI DTIKQSSFLS ADLLPSLGAR INQSTKLRKH IISPFNPRYR AWEMWLVLLV IYSAWICPFQ FAFITYKKDA IFIIDNIVNG
101: FFAIDIILTF FVAYLDSHSY LLVDSPKKIA IRYLSTWFAF DVCSTAPFQP LSLLFNYNGS ELGFRILSML RLWRLRRVSS LFARLEKDIR FNYFWIRCTK
201: LISVTLFAIH CAGCFNYLIA DRYPNPRKTW IGAVYPNFKE ASLWNRYVTA LYWSITTLTT TGYGDFHAEN PREMLFDIFF MMFNLGLTAY LIGNMTNLVV
301: HWTSRTRTFR DSVRAASEFA SRNQLPHDIQ DQMLSHICLK FKTEGLKQQE TLNNLPKAIR SSIANYLFFP IVHNIYLFQG VSRNFLFQLV SDIDAEYFPP
401: KEDIILQNEA PTDLYILVSG AVDFTVYVDG HDQFQGKAVI GETFGEVGVL YYRPQPFTVR TTELSQILRI SRTSLMSAMH AHADDGRVIM NNLFMKLRGQ
501: QSIAIDDSNT SGHENRDFKS MGWEEWRDSR KDGYGLDVTN PTSDTALMDA IHKEDTEMVK KILKEQKIER AKVERSSSET AGRSYANDSS KKDPYCSSSN
601: QIIKPCKREE KRVTIHMMSE SKNGKLILLP SSIEELLRLA SEKFGGCNFT KITNADNAEI DDLDVIWDGD HLYFSSN
See Also
Citation
If you find this resource useful please cite one of the following publications:

Hooper CM, Castleden I, Tanz SK, Aryamanesh, and Millar, AH (2017) SUBA4: the interactive data analysis centre for Arabidopsis subcellular protein locations Nucleic Acids Res. Jan 4;45(D1):D1064-D1074. doi: 10.1093/nar/gkw1041 (PubMed)

Hooper CM, Tanz SK, Castleden IR, Vacher MA, Small ID, Millar AH (2014) "SUBAcon: a consensus algorithm for unifying the subcellular localization data of the Arabidopsis proteome. Bioinformatics." 1;30(23):3356-64. (Bioinformatics) (PubMed)