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AT5G44070.1
Subcellular Consensus
(Prediction and Experimental)

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SUBAcon:
cytosol 0.997
What is SUBAcon?
What is ASURE?
SUBAcon computations
Experimental Localisations and PPI
FP MS/MS PPI
  • PMID:27943495 (2017): mitochondrion
  • PMID:26781341 (2016): plasma membrane
  • PMID:26572690 (2016): extracellular region plant-type cell wall
  • PMID:22215637 (2012): plasma membrane
  • PMID:21166475 (2011): cytosol
  • PMID:15574830 (2004): plasma membrane
SUBAcon links
AGI-AGI relationships
Coexpression PPI
Description (TAIR10) protein_coding : phytochelatin synthase 1 (PCS1)
Curator
Summary (TAIR10)
Phytochelatin synthase gene confers tolerance to cadmium ions. Catalyzes phytochelatin (PC) synthesis from glutathione (GSH) in the presence of Cd2+, Zn2+, Cu2+ and Fe3+, but not by Co2+ or Ni2+.
Computational
Description (TAIR10)
CADMIUM SENSITIVE 1 (CAD1); FUNCTIONS IN: cadmium ion binding, copper ion binding, glutathione gamma-glutamylcysteinyltransferase activity; INVOLVED IN: in 6 processes; LOCATED IN: cytosol; EXPRESSED IN: 24 plant structures; EXPRESSED DURING: 13 growth stages; CONTAINS InterPro DOMAIN/s: Phytochelatin synthase, C-terminal (InterPro:IPR015407), Phytochelatin synthase (InterPro:IPR007719); BEST Arabidopsis thaliana protein match is: phytochelatin synthase 2 (TAIR:AT1G03980.1); Has 1807 Blast hits to 1807 proteins in 277 species: Archae - 0; Bacteria - 0; Metazoa - 736; Fungi - 347; Plants - 385; Viruses - 0; Other Eukaryotes - 339 (source: NCBI BLink).
Protein Annotations
BioCyc:ARA:AT5G44070-MONOMERBioCyc:MetaCyc:AT5G44070-MONOMERBioGrid:19680BRENDA:2.3.2.15EC:2.3.2.15eggNOG:ENOG4111H5NeggNOG:KOG0632
EMBL:AB006703EMBL:AF085230EMBL:AF085231EMBL:AF093753EMBL:AF135155EMBL:AF162689EMBL:AF461180
EMBL:AY039951EMBL:AY048257EMBL:AY079384EMBL:CP002688EnsemblPlants:AT5G44070EnsemblPlants:AT5G44070.1entrez:834430
GeneID:834430Genevisible:Q9S7Z3GO:GO:0005507GO:GO:0005829GO:GO:0015446GO:GO:0015700GO:GO:0016756
GO:GO:0042344GO:GO:0042742GO:GO:0046685GO:GO:0046686GO:GO:0046870GO:GO:0046938GO:GO:0052544
GO:GO:0071992GO:GO:0071994GO:GO:0098655GO:GO:0098656Gramene:AT5G44070.1hmmpanther:PTHR33447hmmpanther:PTHR33447:SF2
HOGENOM:HOG000241441InParanoid:Q9S7Z3IntAct:Q9S7Z3InterPro:IPR007719InterPro:IPR015407iPTMnet:Q9S7Z3KEGG:ath:AT5G44070
KO:K05941MEROPS:C83.002OMA:DMLLPMSPaxDb:Q9S7Z3Pfam:PF05023Pfam:PF09328Pfam:Q9S7Z3
Pfscan:PS51443PhylomeDB:Q9S7Z3PRIDE:Q9S7Z3PRO:PR:Q9S7Z3PROSITE:PS51443ProteinModelPortal:Q9S7Z3Proteomes:UP000006548
RefSeq:NP_199220.1SABIO-RK:Q9S7Z3SMR:Q9S7Z3STRING:3702.AT5G44070.1SUPFAM:SSF54001TAIR:AT5G44070tair10-symbols:ARA8
tair10-symbols:ATPCS1tair10-symbols:CAD1tair10-symbols:PCS1UniGene:At.7305UniProt:Q9S7Z3
Coordinates (TAIR10) chr5:+:17734876..17737672
Molecular Weight (calculated) 54477.50 Da
IEP (calculated) 6.57
GRAVY (calculated) -0.24
Length 485 amino acids
Sequence (TAIR10)
(BLAST)
001: MAMASLYRRS LPSPPAIDFS SAEGKLIFNE ALQKGTMEGF FRLISYFQTQ SEPAYCGLAS LSVVLNALSI DPGRKWKGPW RWFDESMLDC CEPLEVVKEK
101: GISFGKVVCL AHCSGAKVEA FRTSQSTIDD FRKFVVKCTS SENCHMISTY HRGVFKQTGT GHFSPIGGYN AERDMALILD VARFKYPPHW VPLKLLWEAM
201: DSIDQSTGKR RGFMLISRPH REPGLLYTLS CKDESWIEIA KYLKEDVPRL VSSQHVDSVE KIISVVFKSL PSNFNQFIRW VAEIRITEDS NQNLSAEEKS
301: RLKLKQLVLK EVHETELFKH INKFLSTVGY EDSLTYAAAK ACCQGAEILS GSPSKEFCCR ETCVKCIKGP DDSEGTVVTG VVVRDGNEQK VDLLVPSTQT
401: ECECGPEATY PAGNDVFTAL LLALPPQTWS GIKDQALMHE MKQLISMASL PTLLQEEVLH LRRQLQLLKR CQENKEEDDL AAPAY
See Also
Citation
If you find this resource useful please cite one of the following publications:

Hooper CM, Castleden I, Tanz SK, Aryamanesh, and Millar, AH (2017) SUBA4: the interactive data analysis centre for Arabidopsis subcellular protein locations Nucleic Acids Res. Jan 4;45(D1):D1064-D1074. doi: 10.1093/nar/gkw1041 (PubMed)

Hooper CM, Tanz SK, Castleden IR, Vacher MA, Small ID, Millar AH (2014) "SUBAcon: a consensus algorithm for unifying the subcellular localization data of the Arabidopsis proteome. Bioinformatics." 1;30(23):3356-64. (Bioinformatics) (PubMed)