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AT5G43940.1
Subcellular Consensus
(Prediction and Experimental)
min: heatmap :max

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SUBAcon:
peroxisome 1.000
What is SUBAcon?
Experimental Localisations and PPI
FP MS/MS PPI
  • PMID:31975158 (2020): plastid
  • PMID:31871212 (2020): mitochondrion
  • PMID:31520498 (2020): mitochondrion
  • PMID:31186290 (2019): cytosol None
  • PMID:31023727 (2019): mitochondrion
  • PMID:30962257 (2019): plastid
  • PMID:30783145 (2019): extracellular region plant-type cell wall
  • PMID:30447334 (2019): plasma membrane
  • PMID:29104584 (2017): nucleus nuclear matrix nucleolus
  • PMID:28865150 (2017): extracellular region plant-type cell wall
  • PMID:27122571 (2016): mitochondrion
  • PMID:26781341 (2016): plasma membrane
  • PMID:26572690 (2016): extracellular region plant-type cell wall
  • PMID:25641898 (2015): plasma membrane
  • PMID:24361574 (2014): plastid plastid stroma
  • PMID:23673981 (2013): plastid plastid stroma plastoglobules
  • PMID:21166475 (2011): cytosol
  • PMID:19334764 (2009): plasma membrane
  • PMID:19329564 (2009): peroxisome
  • PMID:17951448 (2007): peroxisome
  • PMID:15574830 (2004): plasma membrane
FP Images

Arabidopsis cell culture (peroxisomal marker)

At5g-GFP-43940
(full-length)
RFP-peroxisomal markeroverlay

Images by John Bussel

onion epidermal cell layer (peroxisomal marker)

At5g-GFP-43940
(full-length)
RFP-peroxisomal markeroverlay

Images by John Bussel
SUBAcon links
AGI-AGI relationships
Coexpression PPI
no PPI data
Description (TAIR10) protein_coding : GroES-like zinc-binding dehydrogenase family protein
Curator
Summary (TAIR10)
Encodes a glutathione-dependent formaldehyde dehydrogenase (also known as class III type alcohol dehydrogenase) reduces S-nitrosoglutathione (GSNO), the condensation product of glutathione and NO, that is a naturally occurring NO reservoir and also a reactive nitrogen intermediate. Gene expression is reduced by wounding and induced by salicylic acid. Is required for the acclimation of plants to high temperature and for fertility.
Computational
Description (TAIR10)
sensitive to hot temperatures 5 (HOT5); FUNCTIONS IN: S-(hydroxymethyl)glutathione dehydrogenase activity, S-nitrosoglutathione reductase activity; INVOLVED IN: in 6 processes; LOCATED IN: peroxisome; EXPRESSED IN: 23 plant structures; EXPRESSED DURING: 14 growth stages; CONTAINS InterPro DOMAIN/s: GroES-like (InterPro:IPR011032), Alcohol dehydrogenase GroES-like (InterPro:IPR013154), Alcohol dehydrogenase, zinc-containing, conserved site (InterPro:IPR002328), Alcohol dehydrogenase, C-terminal (InterPro:IPR013149), Alcohol dehydrogenase class III/S-(hydroxymethyl)glutathione dehydrogenase (InterPro:IPR014183), Alcohol dehydrogenase superfamily, zinc-containing (InterPro:IPR002085); BEST Arabidopsis thaliana protein match is: alcohol dehydrogenase 1 (TAIR:AT1G77120.1); Has 1807 Blast hits to 1807 proteins in 277 species: Archae - 0; Bacteria - 0; Metazoa - 736; Fungi - 347; Plants - 385; Viruses - 0; Other Eukaryotes - 339 (source: NCBI BLink).
Protein Annotations
BioCyc:ARA:AT5G43940-MONOMERBioCyc:ARA:GQT-1380-MONOMERBioGrid:19667EC:1.1.1.-
EC:1.1.1.1EC:1.1.1.284eggNOG:COG1062eggNOG:KOG0022
EMBL:AB006703EMBL:AK226412EMBL:AY039601EMBL:AY087250
EMBL:BT010169EMBL:CP002688EMBL:U63931EMBL:X82647
EnsemblPlants:AT5G43940EnsemblPlants:AT5G43940.1entrez:834417ExpressionAtlas:Q96533
Gene3D:3.40.50.720Gene3D:3.90.180.10GeneID:834417Genevisible:Q96533
GO:GO:0004022GO:GO:0005737GO:GO:0006069GO:GO:0008270
GO:GO:0051903gramene_pathway:1.1.1.284gramene_pathway:PWY-1801hmmpanther:PTHR11695
hmmpanther:PTHR11695:SF269HOGENOM:HOG000294674InParanoid:Q96533InterPro:IPR002085
InterPro:IPR002328InterPro:IPR011032InterPro:IPR013149InterPro:IPR013154
InterPro:IPR014183InterPro:IPR016040KEGG:00010+1.1.1.1KEGG:00040+1.1.1.-
KEGG:00051+1.1.1.-KEGG:00071+1.1.1.1KEGG:00140+1.1.1.-KEGG:00240+1.1.1.-
KEGG:00253+1.1.1.-KEGG:00260+1.1.1.1KEGG:00350+1.1.1.1KEGG:00362+1.1.1.-
KEGG:00363+1.1.1.-KEGG:00365+1.1.1.-KEGG:00400+1.1.1.-KEGG:00520+1.1.1.-
KEGG:00523+1.1.1.-KEGG:00591+1.1.1.-KEGG:00592+1.1.1.1KEGG:00622+1.1.1.-
KEGG:00625+1.1.1.1+1.1.1.-KEGG:00626+1.1.1.1KEGG:00633+1.1.1.-KEGG:00640+1.1.1.-
KEGG:00650+1.1.1.-KEGG:00680+1.1.1.284+1.1.1.-KEGG:00720+1.1.1.-KEGG:00750+1.1.1.-
KEGG:00830+1.1.1.1+1.1.1.-KEGG:00950+1.1.1.-KEGG:00966+1.1.1.-KEGG:00980+1.1.1.1
KEGG:00981+1.1.1.-KEGG:00982+1.1.1.1PANTHER:PTHR11695PaxDb:Q96533
PDB:3UKOPDB:4GL4PDB:4JJIPDB:4L0Q
PDBsum:3UKOPDBsum:4GL4PDBsum:4JJIPDBsum:4L0Q
Pfam:PF00107Pfam:PF08240Pfam:Q96533PhylomeDB:Q96533
PIR:S71244PRIDE:Q96533PRO:PR:Q96533PROSITE:PS00059
ProteinModelPortal:Q96533Proteomes:UP000006548Reactome:R-ATH-71384RefSeq:NP_199207.1
SABIO-RK:Q96533scanprosite:PS00059SMR:Q96533STRING:3702.AT5G43940.2
SUPFAM:SSF50129SUPFAM:SSF51735TAIR:AT5G43940tair10-symbols:ADH2
tair10-symbols:ATGSNOR1tair10-symbols:GSNORtair10-symbols:HOT5tair10-symbols:PAR2
TIGRfam:TIGR02818TIGRFAMs:TIGR02818UniGene:At.23457UniGene:At.63885
UniProt:Q96533
Coordinates (TAIR10) chr5:+:17684265..17686379
Molecular Weight (calculated) 40701.00 Da
IEP (calculated) 6.94
GRAVY (calculated) -0.02
Length 379 amino acids
Sequence (TAIR10)
(BLAST)
001: MATQGQVITC KAAVAYEPNK PLVIEDVQVA PPQAGEVRIK ILYTALCHTD AYTWSGKDPE GLFPCILGHE AAGIVESVGE GVTEVQAGDH VIPCYQAECR
101: ECKFCKSGKT NLCGKVRSAT GVGIMMNDRK SRFSVNGKPI YHFMGTSTFS QYTVVHDVSV AKIDPTAPLD KVCLLGCGVP TGLGAVWNTA KVEPGSNVAI
201: FGLGTVGLAV AEGAKTAGAS RIIGIDIDSK KYETAKKFGV NEFVNPKDHD KPIQEVIVDL TDGGVDYSFE CIGNVSVMRA ALECCHKGWG TSVIVGVAAS
301: GQEISTRPFQ LVTGRVWKGT AFGGFKSRTQ VPWLVEKYMN KEIKVDEYIT HNLTLGEINK AFDLLHEGTC LRCVLDTSK
See Also
Citation
If you find this resource useful please cite one of the following publications:

Hooper CM, Castleden I, Tanz SK, Aryamanesh, and Millar, AH (2017) SUBA4: the interactive data analysis centre for Arabidopsis subcellular protein locations Nucleic Acids Res. Jan 4;45(D1):D1064-D1074. doi: 10.1093/nar/gkw1041 (PubMed)

Hooper CM, Tanz SK, Castleden IR, Vacher MA, Small ID, Millar AH (2014) "SUBAcon: a consensus algorithm for unifying the subcellular localization data of the Arabidopsis proteome. Bioinformatics." 1;30(23):3356-64. (Bioinformatics) (PubMed)