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AT5G41370.1
Subcellular Consensus
(Prediction and Experimental)
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SUBAcon:
nucleus 1.000
ASURE: nucleus
What is SUBAcon?
Experimental Localisations and PPI
FP MS/MS PPI
  • PMID:28865150 (2017): extracellular region plant-type cell wall
SUBAcon links
AGI-AGI relationships
Coexpression PPI
Description (TAIR10) protein_coding : homolog of xeroderma pigmentosum complementation group B 1
Curator
Summary (TAIR10)
Encodes XPB1, a DNA repair protein and transcription factor. Arabidopsis thaliana has duplicated XPB gene (AtXPB1 and AtXPB2, with high similarity to each other). XPB proteins are involved in both DNA repair and transcription, they are component of the transcription factor IIH (TFIIH) and are responsible for DNA helicase activity during nucleotide (nt) excision repair (NER). Complementation assays in yeast rad25 mutant strains suggest the involvement of AtXPB2 in DNA repair. Although both genes are expressed in a constitutive manner during the plant life cycle, Northern blot analyses suggest that light modulates the expression level of both XPB copies.
Computational
Description (TAIR10)
homolog of xeroderma pigmentosum complementation group B 1 (XPB1); FUNCTIONS IN: in 7 functions; INVOLVED IN: response to UV, response to toxin; LOCATED IN: nucleus, cytoplasm; EXPRESSED IN: whole plant, male gametophyte, pollen tube; EXPRESSED DURING: L mature pollen stage, M germinated pollen stage, seedling growth; CONTAINS InterPro DOMAIN/s: Restriction endonuclease, type I, R subunit/Type III, Res subunit (InterPro:IPR006935), DEAD-like helicase, N-terminal (InterPro:IPR014001), Xeroderma pigmentosum group B protein (XP-B) (InterPro:IPR001161), DNA/RNA helicase, C-terminal (InterPro:IPR001650), Helicase, superfamily 1/2, ATP-binding domain (InterPro:IPR014021); BEST Arabidopsis thaliana protein match is: homolog of Xeroderma pigmentosum complementation group B 2 (TAIR:AT5G41360.1); Has 30201 Blast hits to 17322 proteins in 780 species: Archae - 12; Bacteria - 1396; Metazoa - 17338; Fungi - 3422; Plants - 5037; Viruses - 0; Other Eukaryotes - 2996 (source: NCBI BLink).
Protein Annotations
BioCyc:ARA:GQT-1908-MONOMERBioGrid:19390EC:3.6.4.12eggNOG:COG1061
eggNOG:KOG1123EMBL:AB006707EMBL:AY039547EMBL:AY113008
EMBL:AY550923EMBL:CP002688EMBL:U29168EnsemblPlants:AT5G41370
EnsemblPlants:AT5G41370.1entrez:834139Gene3D:3.40.50.300GeneID:834139
Genevisible:Q38861GO:GO:0003677GO:GO:0004003GO:GO:0005524
GO:GO:0005634GO:GO:0005737GO:GO:0006289GO:GO:0006355
GO:GO:0006367GO:GO:0009411Gramene:AT5G41370.1hmmpanther:PTHR11274
hmmpanther:PTHR11274:SF0HOGENOM:HOG000160172InParanoid:Q38861IntAct:Q38861
InterPro:IPR001161InterPro:IPR001650InterPro:IPR006935InterPro:IPR014001
InterPro:IPR027417InterPro:IPR032438InterPro:IPR032830iPTMnet:Q38861
KEGG:ath:AT5G41370KO:K10843MINT:MINT-8070993OMA:REREWGL
PaxDb:Q38861Pfam:PF04851Pfam:PF13625Pfam:PF16203
Pfam:Q38861Pfscan:PS51192Pfscan:PS51194PhylomeDB:Q38861
PIR:S71206PRIDE:Q38861PRO:PR:Q38861PROSITE:PS51192
PROSITE:PS51194ProteinModelPortal:Q38861Proteomes:UP000006548Reactome:R-ATH-113418
Reactome:R-ATH-5696395Reactome:R-ATH-5696400Reactome:R-ATH-674695Reactome:R-ATH-6781823
Reactome:R-ATH-6782135Reactome:R-ATH-6782210Reactome:R-ATH-72086Reactome:R-ATH-73776
Reactome:R-ATH-73779Reactome:R-ATH-75953Reactome:R-ATH-76042Reactome:R-ATH-77075
RefSeq:NP_568592.1SMART:SM00487SMART:SM00490SMR:Q38861
STRING:3702.AT5G41370.1SUPFAM:SSF52540TAIR:AT5G41370tair10-symbols:ATXPB1
tair10-symbols:XPB1TIGRfam:TIGR00603TIGRFAMs:TIGR00603UniGene:At.6482
UniProt:Q38861
Coordinates (TAIR10) chr5:+:16551337..16555792
Molecular Weight (calculated) 87067.20 Da
IEP (calculated) 8.26
GRAVY (calculated) -0.54
Length 767 amino acids
Sequence (TAIR10)
(BLAST)
001: MGNGERGRPN KKMKYGGKDD QKMKNIQNAE DYYDDADEDS RDGEGEEKKR DFTKLELKPD HGNRPLWACA DGRIFLETFS PLYKQAYDFL IAIAEPVCRP
101: ESMHEYNLTP HSLYAAVSVG LETETIISVL NKLSKTKLPK EMIEFIHAST ANYGKVKLVL KKNRYFIESP FPEVLKRLLS DDVINRARFS SEPYYGGDGF
201: SVGRTCGELE AGPGELLNEA EFAAAAEEKE THSFEIDPAQ VENVKQRCLP NALNYPMLEE YDFRNDNVNP DLDMELKPHA QPRPYQEKSL SKMFGNGRAR
301: SGIIVLPCGA GKSLVGVSAA ARIKKSCLCL ATNAVSVDQW AFQFKLWSTI RDDQICRFTS DSKERFRGNA GVVVTTYNMV AFGGKRSEES EKIIEEMRNR
401: EWGLLLMDEV HVVPAHMFRK VISITKSHCK LGLTATLVRE DERITDLNFL IGPKLYEANW LDLVKGGFIA NVQCAEVWCP MTKEFFAEYL KKENSKKKQA
501: LYVMNPNKFR ACEFLIRFHE QQRGDKIIVF ADNLFALTEY AMKLRKPMIY GATSHIERTK ILEAFKTSKD VNTVFLSKVG DNSIDIPEAN VIIQISSHAG
601: SRRQEAQRLG RILRAKGKLE DRMAGGKEEY NAFFYSLVST DTQEMYYSTK RQQFLIDQGY SFKVITSLPP PDAGSSLSYH SQEEQLSLLG KVMNAGDDLV
701: GLEQLEEDTD GMALQKARRS MGSMSVMSGS KGMVYMEYNS GRHKSGQQFK KPKDPTKRHN LFKKRYV
See Also
Citation
If you find this resource useful please cite one of the following publications:

Hooper CM, Castleden I, Tanz SK, Aryamanesh, and Millar, AH (2017) SUBA4: the interactive data analysis centre for Arabidopsis subcellular protein locations Nucleic Acids Res. Jan 4;45(D1):D1064-D1074. doi: 10.1093/nar/gkw1041 (PubMed)

Hooper CM, Tanz SK, Castleden IR, Vacher MA, Small ID, Millar AH (2014) "SUBAcon: a consensus algorithm for unifying the subcellular localization data of the Arabidopsis proteome. Bioinformatics." 1;30(23):3356-64. (Bioinformatics) (PubMed)