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AT5G40890.1
Subcellular Consensus
(Prediction and Experimental)
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SUBAcon:
vacuole 1.000
ASURE: vacuole
What is SUBAcon?
Experimental Localisations and PPI
FP MS/MS PPI
  • PMID:31615849 (2019): plastid plastid thylakoid
  • PMID:30962257 (2019): plastid
  • PMID:30447334 (2019): plasma membrane
  • PMID:26748395 (2016): plant-type vacuole plant-type vacuole membrane
  • PMID:25900983 (2015): Golgi
  • PMID:25900983 (2015): Golgi Golgi apparatus Golgi membrane
  • PMID:25900983 (2015): Golgi trans-Golgi network
  • PMID:25900983 (2015): Golgi trans-Golgi network early endosome
  • PMID:25900983 (2015): Golgi trans-Golgi network multivesicular body
  • PMID:25641898 (2015): plasma membrane
  • PMID:21988472 (2012): plant-type vacuole plant-type vacuole membrane
SUBAcon links
AGI-AGI relationships
Coexpression PPI
Description (TAIR10) protein_coding : chloride channel A
Curator
Summary (TAIR10)
Encodes a member of the voltage-dependent chloride channel. Also functions as a NO3-/H+ exchanger that serves to accumulate nitrate nutrient in vacuoles. Mutants homozygous for the T-DNA insertion mutation have reduced nitrate uptake capacity in high nitrate environment and exhibit hypersensitivity to chlorate.
Computational
Description (TAIR10)
chloride channel A (CLC-A); CONTAINS InterPro DOMAIN/s: Chloride channel, core (InterPro:IPR014743), Chloride channel, voltage gated (InterPro:IPR001807), Chloride channel ClC-plant (InterPro:IPR002251), Cystathionine beta-synthase, core (InterPro:IPR000644); BEST Arabidopsis thaliana protein match is: chloride channel B (TAIR:AT3G27170.1); Has 1807 Blast hits to 1807 proteins in 277 species: Archae - 0; Bacteria - 0; Metazoa - 736; Fungi - 347; Plants - 385; Viruses - 0; Other Eukaryotes - 339 (source: NCBI BLink).
Protein Annotations
BioGrid:19341eggNOG:COG0038eggNOG:KOG0474EMBL:AB011477
EMBL:AF044313EMBL:AY059791EMBL:AY150506EMBL:CP002688
EMBL:Z71445EnsemblPlants:AT5G40890EnsemblPlants:AT5G40890.1entrez:834090
ExpressionAtlas:P92941Gene3D:1.10.3080.10GeneID:834090Genevisible:P92941
GO:GO:0005247GO:GO:0005622GO:GO:0006821GO:GO:0010167
GO:GO:0015112GO:GO:0015706GO:GO:0034707hmmpanther:PTHR11689
hmmpanther:PTHR11689:SF67HOGENOM:HOG000231081InParanoid:P92941IntAct:P92941
InterPro:IPR000644InterPro:IPR001807InterPro:IPR002251InterPro:IPR014743
iPTMnet:P92941OMA:KQFNCPDPaxDb:P92941Pfam:P92941
Pfam:PF00571Pfam:PF00654Pfscan:PS51371PhylomeDB:P92941
PIR:T52107PRIDE:P92941PRINTS:PR00762PRINTS:PR01120
PRO:PR:P92941PROSITE:PS51371ProteinModelPortal:P92941Proteomes:UP000006548
Reactome:R-ATH-2672351RefSeq:NP_198905.1SMART:SM00116SMR:P92941
STRING:3702.AT5G40890.1SUPFAM:SSF54631SUPFAM:SSF81340TAIR:AT5G40890
tair10-symbols:ATCLC-Atair10-symbols:ATCLCAtair10-symbols:CLC-Atair10-symbols:CLCA
TMHMM:TMhelixUniGene:At.25457UniProt:P92941
Coordinates (TAIR10) chr5:-:16381645..16384999
Molecular Weight (calculated) 85411.30 Da
IEP (calculated) 7.25
GRAVY (calculated) 0.24
Length 775 amino acids
Sequence (TAIR10)
(BLAST)
001: MDEDGNLQIS NSNYNGEEEG EDPENNTLNQ PLLKRHRTLS STPLALVGAK VSHIESLDYE INENDLFKHD WRSRSKAQVF QYIFLKWTLA CLVGLFTGLI
101: ATLINLAVEN IAGYKLLAVG YYIAQDRFWT GLMVFTGANL GLTLVATVLV VYFAPTAAGP GIPEIKAYLN GIDTPNMFGF TTMMVKIVGS IGAVAAGLDL
201: GKEGPLVHIG SCIASLLGQG GPDNHRIKWR WLRYFNNDRD RRDLITCGSA SGVCAAFRSP VGGVLFALEE VATWWRSALL WRTFFSTAVV VVVLRAFIEI
301: CNSGKCGLFG SGGLIMFDVS HVEVRYHAAD IIPVTLIGVF GGILGSLYNH LLHKVLRLYN LINQKGKIHK VLLSLGVSLF TSVCLFGLPF LAECKPCDPS
401: IDEICPTNGR SGNFKQFNCP NGYYNDLSTL LLTTNDDAVR NIFSSNTPNE FGMVSLWIFF GLYCILGLIT FGIATPSGLF LPIILMGSAY GRMLGTAMGS
501: YTNIDQGLYA VLGAASLMAG SMRMTVSLCV IFLELTNNLL LLPITMFVLL IAKTVGDSFN LSIYEIILHL KGLPFLEANP EPWMRNLTVG ELNDAKPPVV
601: TLNGVEKVAN IVDVLRNTTH NAFPVLDGAD QNTGTELHGL ILRAHLVKVL KKRWFLNEKR RTEEWEVREK FTPVELAERE DNFDDVAITS SEMQLYVDLH
701: PLTNTTPYTV VQSMSVAKAL VLFRSVGLRH LLVVPKIQAS GMSPVIGILT RQDLRAYNIL QAFPHLDKHK SGKAR
See Also
Citation
If you find this resource useful please cite one of the following publications:

Hooper CM, Castleden I, Tanz SK, Aryamanesh, and Millar, AH (2017) SUBA4: the interactive data analysis centre for Arabidopsis subcellular protein locations Nucleic Acids Res. Jan 4;45(D1):D1064-D1074. doi: 10.1093/nar/gkw1041 (PubMed)

Hooper CM, Tanz SK, Castleden IR, Vacher MA, Small ID, Millar AH (2014) "SUBAcon: a consensus algorithm for unifying the subcellular localization data of the Arabidopsis proteome. Bioinformatics." 1;30(23):3356-64. (Bioinformatics) (PubMed)