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AT5G27380.1
Subcellular Consensus
(Prediction and Experimental)
min: heatmap :max

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SUBAcon:
cytosol 0.500
plastid 0.500
ASURE: cytosol,plastid
What is SUBAcon?
Experimental Localisations and PPI
FP MS/MS PPI
  • PMID:31520498 (2020): mitochondrion
  • PMID:31186290 (2019): plastid plastid stroma
  • PMID:30783145 (2019): extracellular region plant-type cell wall
  • PMID:30135097 (2018): plastid
  • PMID:28865150 (2017): extracellular region plant-type cell wall
  • PMID:27122571 (2016): mitochondrion
  • PMID:24361574 (2014): plastid plastid stroma
  • PMID:24124904 (2013): plastid
  • PMID:22550958 (2012): plastid
  • PMID:21166475 (2011): cytosol
  • PMID:15574830 (2004): plasma membrane
SUBAcon links
AGI-AGI relationships
Coexpression PPI
no PPI data
Description (TAIR10) protein_coding : glutathione synthetase 2
Curator
Summary (TAIR10)
Encodes a protein with similarity to glutathione synthetases, which catalyzes one of the early steps in glutathione biosynthesis. Two transcripts have been detected; the longer transcript is less abundant and the protein is localized to the chloroplast. The smaller transcript, in which the transit peptide is truncated, is localized to the cytosol.
Computational
Description (TAIR10)
glutathione synthetase 2 (GSH2); FUNCTIONS IN: glutathione synthase activity; INVOLVED IN: response to jasmonic acid stimulus, N-terminal protein myristoylation, glutathione biosynthetic process; LOCATED IN: cytosol, chloroplast; EXPRESSED IN: 25 plant structures; EXPRESSED DURING: 14 growth stages; CONTAINS InterPro DOMAIN/s: PreATP-grasp-like fold (InterPro:IPR016185), ATP-grasp fold, subdomain 2 (InterPro:IPR013816), Glutathione synthase, eukaryotic (InterPro:IPR005615), Glutathione synthase, substrate-binding, eukaryotic (InterPro:IPR004887), Glutathione synthase, alpha-helical, eukaryotic (InterPro:IPR014042); Has 644 Blast hits to 607 proteins in 239 species: Archae - 0; Bacteria - 51; Metazoa - 212; Fungi - 156; Plants - 112; Viruses - 0; Other Eukaryotes - 113 (source: NCBI BLink).
Protein Annotations
BioCyc:ARA:AT5G27380-MONOMERBioGrid:18071BRENDA:6.3.2.3EC:6.3.2.3
eggNOG:ENOG410XPHHeggNOG:KOG0021EMBL:AC007123EMBL:AF424586
EMBL:AJ243812EMBL:AJ243813EMBL:BT000624EMBL:CP002688
EMBL:U22359EMBL:U53856EMBL:X83411EMBL:Z50153
EnsemblPlants:AT5G27380EnsemblPlants:AT5G27380.1entrez:832797Gene3D:1.10.1080.10
Gene3D:3.30.1490.50Gene3D:3.30.1490.80Gene3D:3.40.50.1760GeneID:832797
Genevisible:P46416GO:GO:0000287GO:GO:0004363GO:GO:0005524
GO:GO:0005829GO:GO:0006750GO:GO:0009507GO:GO:0009753
GO:GO:0042803GO:GO:0043295Gramene:AT5G27380.1gramene_plant_reactome:1119342
gramene_plant_reactome:6874585hmmpanther:PTHR11130hmmpanther:PTHR11130:SF0HOGENOM:HOG000172641
InParanoid:P46416InterPro:IPR004887InterPro:IPR005615InterPro:IPR014042
InterPro:IPR014049InterPro:IPR014709InterPro:IPR016185iPTMnet:P46416
KEGG:00270+6.3.2.3KEGG:00480+6.3.2.3KEGG:ath:AT5G27380KO:K01920
OMA:SHWKQACPANTHER:PTHR11130PaxDb:P46416Pfam:P46416
Pfam:PF03199Pfam:PF03917PhylomeDB:P46416PIR:S62654
PIR:S68223PIR:T52565PIRSF:PIRSF001558PRIDE:P46416
PRO:PR:P46416ProteinModelPortal:P46416Proteomes:UP000006548Reactome:R-ATH-174403
RefSeq:NP_568495.2SMR:P46416STRING:3702.AT5G27380.1SUPFAM:SSF52440
SUPFAM:SSF56059TAIR:AT5G27380tair10-symbols:GSH2tair10-symbols:GSHB
TIGRfam:TIGR01986TIGRFAMs:TIGR01986UniGene:At.21515UniGene:At.55036
UniPathway:UPA00142UniProt:P46416
Coordinates (TAIR10) chr5:-:9668211..9670912
Molecular Weight (calculated) 60274.10 Da
IEP (calculated) 6.45
GRAVY (calculated) -0.27
Length 539 amino acids
Sequence (TAIR10)
(BLAST)
001: MGSGCSSLSY SSSSTCNATV FSISSSPSSS SSLKLNPSSF LFQNPKTLRN QSPLRCGRSF KMESQKPIFD LEKLDDEFVQ KLVYDALVWS SLHGLVVGDK
101: SYQKSGNVPG VGLMHAPIAL LPTAFPEAYW KQACNVTPLF NELIDRVSLD GKFLQDSLSR TKKVDVFTSR LLDIHSKMLE RNKKEDIRLG LHRFDYMLDE
201: ETNSLLQIEM NTISCSFPGL SRLVSQLHQS LLRSYGDQIG IDSERVPINT STIQFADALA KAWLEYSNPR AVVMVIVQPE ERNMYDQHLL SSILREKHNI
301: VVIRKTLAEV EKEGSVQEDE TLIVGGQAVA VVYFRSGYTP NDHPSESEWN ARLLIEESSA VKCPSIAYHL TGSKKIQQEL AKPGVLERFL DNKEDIAKLR
401: KCFAGLWSLD DSEIVKQAIE KPGLFVMKPQ REGGGNNIYG DDVRENLLRL QKEGEEGNAA YILMQRIFPK VSNMFLVREG VYHKHQAISE LGVYGAYLRS
501: KDEVIVNEQS GYLMRTKIAS SDEGGVAAGF GVLDSIYLI
See Also
Citation
If you find this resource useful please cite one of the following publications:

Hooper CM, Castleden I, Tanz SK, Aryamanesh, and Millar, AH (2017) SUBA4: the interactive data analysis centre for Arabidopsis subcellular protein locations Nucleic Acids Res. Jan 4;45(D1):D1064-D1074. doi: 10.1093/nar/gkw1041 (PubMed)

Hooper CM, Tanz SK, Castleden IR, Vacher MA, Small ID, Millar AH (2014) "SUBAcon: a consensus algorithm for unifying the subcellular localization data of the Arabidopsis proteome. Bioinformatics." 1;30(23):3356-64. (Bioinformatics) (PubMed)