suba logo
AT5G27380.1
Subcellular Consensus
(Prediction and Experimental)

min: heatmap :max

.
SUBAcon:
cytosol 0.500
plastid 0.500
ASURE: cytosol,plastid
What is SUBAcon?
What is ASURE?
SUBAcon computations
Experimental Localisations and PPI
FP MS/MS PPI
SUBAcon links
AGI-AGI relationships
Coexpression PPI
no PPI data
Description (TAIR10) protein_coding : glutathione synthetase 2
Curator
Summary (TAIR10)
Encodes a protein with similarity to glutathione synthetases, which catalyzes one of the early steps in glutathione biosynthesis. Two transcripts have been detected; the longer transcript is less abundant and the protein is localized to the chloroplast. The smaller transcript, in which the transit peptide is truncated, is localized to the cytosol.
Computational
Description (TAIR10)
glutathione synthetase 2 (GSH2); FUNCTIONS IN: glutathione synthase activity; INVOLVED IN: response to jasmonic acid stimulus, N-terminal protein myristoylation, glutathione biosynthetic process; LOCATED IN: cytosol, chloroplast; EXPRESSED IN: 25 plant structures; EXPRESSED DURING: 14 growth stages; CONTAINS InterPro DOMAIN/s: PreATP-grasp-like fold (InterPro:IPR016185), ATP-grasp fold, subdomain 2 (InterPro:IPR013816), Glutathione synthase, eukaryotic (InterPro:IPR005615), Glutathione synthase, substrate-binding, eukaryotic (InterPro:IPR004887), Glutathione synthase, alpha-helical, eukaryotic (InterPro:IPR014042); Has 644 Blast hits to 607 proteins in 239 species: Archae - 0; Bacteria - 51; Metazoa - 212; Fungi - 156; Plants - 112; Viruses - 0; Other Eukaryotes - 113 (source: NCBI BLink).
Protein Annotations
BioCyc:ARA:AT5G27380-MONOMERBioGrid:18071BRENDA:6.3.2.3EC:6.3.2.3eggNOG:ENOG410XPHHeggNOG:KOG0021EMBL:AC007123
EMBL:AF424586EMBL:AJ243812EMBL:AJ243813EMBL:BT000624EMBL:CP002688EMBL:U22359EMBL:U53856
EMBL:X83411EMBL:Z50153EnsemblPlants:AT5G27380EnsemblPlants:AT5G27380.1entrez:832797Gene3D:1.10.1080.10Gene3D:3.30.1490.50
Gene3D:3.30.1490.80Gene3D:3.40.50.1760GeneID:832797Genevisible:P46416GO:GO:0000287GO:GO:0004363GO:GO:0005524
GO:GO:0005829GO:GO:0006750GO:GO:0009507GO:GO:0009753GO:GO:0042803GO:GO:0043295Gramene:AT5G27380.1
gramene_plant_reactome:1119342gramene_plant_reactome:6874585hmmpanther:PTHR11130hmmpanther:PTHR11130:SF0HOGENOM:HOG000172641InParanoid:P46416InterPro:IPR004887
InterPro:IPR005615InterPro:IPR014042InterPro:IPR014049InterPro:IPR014709InterPro:IPR016185iPTMnet:P46416KEGG:00270+6.3.2.3
KEGG:00480+6.3.2.3KEGG:ath:AT5G27380KO:K01920OMA:SHWKQACPANTHER:PTHR11130PaxDb:P46416Pfam:P46416
Pfam:PF03199Pfam:PF03917PhylomeDB:P46416PIR:S62654PIR:S68223PIR:T52565PIRSF:PIRSF001558
PRIDE:P46416PRO:PR:P46416ProteinModelPortal:P46416Proteomes:UP000006548Reactome:R-ATH-174403RefSeq:NP_568495.2SMR:P46416
STRING:3702.AT5G27380.1SUPFAM:SSF52440SUPFAM:SSF56059TAIR:AT5G27380tair10-symbols:GSH2tair10-symbols:GSHBTIGRfam:TIGR01986
TIGRFAMs:TIGR01986UniGene:At.21515UniGene:At.55036UniPathway:UPA00142UniProt:P46416
Coordinates (TAIR10) chr5:-:9668211..9670912
Molecular Weight (calculated) 60274.10 Da
IEP (calculated) 6.45
GRAVY (calculated) -0.27
Length 539 amino acids
Sequence (TAIR10)
(BLAST)
001: MGSGCSSLSY SSSSTCNATV FSISSSPSSS SSLKLNPSSF LFQNPKTLRN QSPLRCGRSF KMESQKPIFD LEKLDDEFVQ KLVYDALVWS SLHGLVVGDK
101: SYQKSGNVPG VGLMHAPIAL LPTAFPEAYW KQACNVTPLF NELIDRVSLD GKFLQDSLSR TKKVDVFTSR LLDIHSKMLE RNKKEDIRLG LHRFDYMLDE
201: ETNSLLQIEM NTISCSFPGL SRLVSQLHQS LLRSYGDQIG IDSERVPINT STIQFADALA KAWLEYSNPR AVVMVIVQPE ERNMYDQHLL SSILREKHNI
301: VVIRKTLAEV EKEGSVQEDE TLIVGGQAVA VVYFRSGYTP NDHPSESEWN ARLLIEESSA VKCPSIAYHL TGSKKIQQEL AKPGVLERFL DNKEDIAKLR
401: KCFAGLWSLD DSEIVKQAIE KPGLFVMKPQ REGGGNNIYG DDVRENLLRL QKEGEEGNAA YILMQRIFPK VSNMFLVREG VYHKHQAISE LGVYGAYLRS
501: KDEVIVNEQS GYLMRTKIAS SDEGGVAAGF GVLDSIYLI
See Also
Citation
If you find this resource useful please cite one of the following publications:

Hooper CM, Castleden I, Tanz SK, Aryamanesh, and Millar, AH (2017) SUBA4: the interactive data analysis centre for Arabidopsis subcellular protein locations Nucleic Acids Res. Jan 4;45(D1):D1064-D1074. doi: 10.1093/nar/gkw1041 (PubMed)

Hooper CM, Tanz SK, Castleden IR, Vacher MA, Small ID, Millar AH (2014) "SUBAcon: a consensus algorithm for unifying the subcellular localization data of the Arabidopsis proteome. Bioinformatics." 1;30(23):3356-64. (Bioinformatics) (PubMed)