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AT5G24400.1
Subcellular Consensus
(Prediction and Experimental)
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SUBAcon:
peroxisome 0.500
plastid 0.500
ASURE: peroxisome,plastid
What is SUBAcon?
Experimental Localisations and PPI
FP MS/MS PPI
  • PMID:31520498 (2020): mitochondrion
  • PMID:31186290 (2019): plastid plastid stroma
  • PMID:30962257 (2019): plastid
  • PMID:30783145 (2019): extracellular region plant-type cell wall
  • PMID:28865150 (2017): extracellular region plant-type cell wall
  • PMID:26572690 (2016): extracellular region plant-type cell wall
  • PMID:24361574 (2014): plastid plastid stroma
  • PMID:24124904 (2013): plastid
  • PMID:21531424 (2011): plastid
  • PMID:21311031 (2011): mitochondrion
  • PMID:20423899 (2010): plastid
  • PMID:20061580 (2010): plastid plastid stroma
  • PMID:18633119 (2008): plastid plastid stroma
  • PMID:18431481 (2008): plastid plastid stroma
SUBAcon links
AGI-AGI relationships
Coexpression PPI
no PPI data
Description (TAIR10) protein_coding : NagB/RpiA/CoA transferase-like superfamily protein
Curator
Summary (TAIR10)
Encodes a protein with 6-phosphoglucunolactonase activity that localizes to the chloroplasts and the peroxisome. However, mutant phenotypes observed in pgl3 mutant plants can be complemented with a chloroplast-targeted version of the protein. PGL3 likely functions in the oxidative branch of the pentose phosphate pathway. pgl3 mutant phenotypes suggest that it is important in pathogen defense and maintenance of cellular redox homeostasis.
Computational
Description (TAIR10)
EMBRYO DEFECTIVE 2024 (EMB2024); FUNCTIONS IN: 6-phosphogluconolactonase activity, catalytic activity; INVOLVED IN: defense response to oomycetes, defense response to bacterium, carbohydrate metabolic process, cellular response to redox state, embryo development ending in seed dormancy; LOCATED IN: peroxisome, chloroplast stroma, chloroplast; EXPRESSED IN: 22 plant structures; EXPRESSED DURING: 13 growth stages; CONTAINS InterPro DOMAIN/s: Glucosamine/galactosamine-6-phosphate isomerase (InterPro:IPR006148), 6-phosphogluconolactonase, DevB-type (InterPro:IPR005900); BEST Arabidopsis thaliana protein match is: 6-phosphogluconolactonase 2 (TAIR:AT3G49360.1); Has 30201 Blast hits to 17322 proteins in 780 species: Archae - 12; Bacteria - 1396; Metazoa - 17338; Fungi - 3422; Plants - 5037; Viruses - 0; Other Eukaryotes - 2996 (source: NCBI BLink).
Protein Annotations
BioCyc:ARA:AT5G24400-MONOMERBioGrid:17786BRENDA:3.1.1.31EC:3.1.1.31
eggNOG:COG0363eggNOG:KOG3147EMBL:AB016884EMBL:AY086161
EMBL:BT001923EMBL:CP002688EMBL:Z26557EnsemblPlants:AT5G24400
EnsemblPlants:AT5G24400.1entrez:832511GeneID:832511Genevisible:Q84WW2
GO:GO:0002229GO:GO:0005777GO:GO:0005975GO:GO:0006098
GO:GO:0009507GO:GO:0009536GO:GO:0009570GO:GO:0017057
GO:GO:0042128GO:GO:0042742GO:GO:0071461Gramene:AT5G24400.1
hmmpanther:PTHR11054hmmpanther:PTHR11054:SF3HOGENOM:HOG000256285InParanoid:Q84WW2
InterPro:IPR005900InterPro:IPR006148iPTMnet:Q84WW2KEGG:00030+3.1.1.31
KEGG:00520+3.5.99.6KEGG:ath:AT5G24400KO:K01057OMA:EDELVWF
PaxDb:Q84WW2Pfam:PF01182Pfam:Q84WW2PhylomeDB:Q84WW2
PRIDE:Q84WW2PRO:PR:Q84WW2ProteinModelPortal:Q84WW2Proteomes:UP000006548
Reactome:R-ATH-71336RefSeq:NP_568445.1SMR:Q84WW2STRING:3702.AT5G24400.1
SUPFAM:SSF100950TAIR:AT5G24400tair10-symbols:EMB2024tair10-symbols:PGL3
TIGRfam:TIGR01198TIGRFAMs:TIGR01198UniGene:At.19070UniPathway:UPA00115
UniProt:Q84WW2
Coordinates (TAIR10) chr5:-:8330532..8331784
Molecular Weight (calculated) 35646.30 Da
IEP (calculated) 7.87
GRAVY (calculated) -0.18
Length 325 amino acids
Sequence (TAIR10)
(BLAST)
001: MASSSCFLRS ILFSSPTNLR SNHHLPTFFP KNYLICSHST SSRFESLSVS SIGTGSTKKS SDTRRKVKSM ATTNIGKEEK KRVEIYDLEE NLVIDLAKFT
101: ADLSDKFCKE RGAFTVVVSG GSLIKSLRKL VESPYVDSID WARWHFFWVD ERVVPKNHDD SNYKLAYDSF LSKVPIPPGN VYAINEALSA EAAADDYETC
201: LKHLVNTNIL RVSESTGFPK FDLMLLGMGP DGHVASLFPG HGLCNESKKW VVSISDSPKP PSERITFTFP VINSSAHVAL VVCGSGKAEA VEAALKKTGN
301: VPPAGSVSAE DELVWFLDKP ASSKL
See Also
Citation
If you find this resource useful please cite one of the following publications:

Hooper CM, Castleden I, Tanz SK, Aryamanesh, and Millar, AH (2017) SUBA4: the interactive data analysis centre for Arabidopsis subcellular protein locations Nucleic Acids Res. Jan 4;45(D1):D1064-D1074. doi: 10.1093/nar/gkw1041 (PubMed)

Hooper CM, Tanz SK, Castleden IR, Vacher MA, Small ID, Millar AH (2014) "SUBAcon: a consensus algorithm for unifying the subcellular localization data of the Arabidopsis proteome. Bioinformatics." 1;30(23):3356-64. (Bioinformatics) (PubMed)