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AT5G23720.1
Subcellular Consensus
(Prediction and Experimental)

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SUBAcon:
cytosol 0.672
What is SUBAcon?
What is ASURE?
SUBAcon computations
Experimental Localisations and PPI
FP MS/MS PPI
SUBAcon links
AGI-AGI relationships
Coexpression PPI
Description (TAIR10) protein_coding : dual specificity protein phosphatase family protein
Curator
Summary (TAIR10)
Encodes a protein tyrosine phosphatase Propyzamide-Hypersensitive 1 (PHS1). One of the mutant alleles, phs1-1, is hypersensitive to the microtubule-destabilizing drug propyzamide, suggesting that PHS1 may be involved in phosphorylation cascades that control the dynamics of cortical microtubules in plant cells. A second allele, phs1-3, is hypersensitive to abscisic acid, indicating a possible involvement of PHS1 in ABA signalling.
Computational
Description (TAIR10)
PROPYZAMIDE-HYPERSENSITIVE 1 (PHS1); FUNCTIONS IN: protein tyrosine/serine/threonine phosphatase activity, phosphoprotein phosphatase activity; INVOLVED IN: cortical microtubule organization, regulation of gene expression, response to abscisic acid stimulus, regulation of stomatal movement; LOCATED IN: cytoplasm; EXPRESSED IN: 25 plant structures; EXPRESSED DURING: 15 growth stages; CONTAINS InterPro DOMAIN/s: Zinc finger, C2H2-like (InterPro:IPR015880), Dual-specific/protein-tyrosine phosphatase, conserved region (InterPro:IPR000387), Dual specificity phosphatase, subgroup, catalytic domain (InterPro:IPR020422), Protein kinase-like domain (InterPro:IPR011009), Protein-tyrosine phosphatase, active site (InterPro:IPR016130), Actin-fragmin kinase, catalytic (InterPro:IPR015275), Dual specificity phosphatase, catalytic domain (InterPro:IPR000340); BEST Arabidopsis thaliana protein match is: dual specificity protein phosphatase 1 (TAIR:AT3G23610.2); Has 35333 Blast hits to 34131 proteins in 2444 species: Archae - 798; Bacteria - 22429; Metazoa - 974; Fungi - 991; Plants - 531; Viruses - 0; Other Eukaryotes - 9610 (source: NCBI BLink).
Protein Annotations
BioCyc:ARA:AT5G23720-MONOMERBioGrid:17712EC:3.1.3.16EC:3.1.3.48eggNOG:COG2453eggNOG:KOG1716EMBL:AB005244
EMBL:AB025633EMBL:AB161693EMBL:CP002688EnsemblPlants:AT5G23720EnsemblPlants:AT5G23720.1entrez:832437ExpressionAtlas:Q75QN6
Gene3D:1.10.1070.11Gene3D:3.90.190.10GeneID:832437Genevisible:Q75QN6GO:GO:0004721GO:GO:0004725GO:GO:0005737
GO:GO:0008138GO:GO:0009737GO:GO:0009738GO:GO:0010119GO:GO:0010468GO:GO:0016773GO:GO:0043622
hmmpanther:PTHR10159hmmpanther:PTHR10159:SF346HOGENOM:HOG000030291IntAct:Q75QN6InterPro:IPR000340InterPro:IPR000387InterPro:IPR000403
InterPro:IPR011009InterPro:IPR015275InterPro:IPR016130InterPro:IPR020422InterPro:IPR024950InterPro:IPR029021iPTMnet:Q75QN6
OMA:SEISLWEPANTHER:PTHR10159PaxDb:Q75QN6Pfam:PF00782Pfam:PF09192Pfam:Q75QN6Pfscan:PS50054
Pfscan:PS50056PhylomeDB:Q75QN6PRIDE:Q75QN6PRO:PR:Q75QN6PROSITE:PS00383PROSITE:PS50054PROSITE:PS50056
ProteinModelPortal:Q75QN6Proteomes:UP000006548Reactome:R-ATH-202670RefSeq:NP_197761.2RefSeq:NP_851066.2scanprosite:PS00383SMART:SM00195
SMR:Q75QN6STRING:3702.AT5G23720.1SUPFAM:SSF52799SUPFAM:SSF56112TAIR:AT5G23720tair10-symbols:PHS1UniGene:At.22786
UniProt:Q75QN6
Coordinates (TAIR10) chr5:+:7998309..8002594
Molecular Weight (calculated) 104240.00 Da
IEP (calculated) 6.37
GRAVY (calculated) -0.59
Length 929 amino acids
Sequence (TAIR10)
(BLAST)
001: MAEPEKKRDQ PFSQEKDEEK DLYLVHDEHE SPLPLTVTSR VLYMLGDIAS GPAYRFTQWL DLVRKRSATY GSSGFPHRLH RIDDMVTSAG ERNTDPKSPP
101: SRQSSEISLW ERLGKASTVD IDSSCFSWNM LSSLHHTEHS SSTDHSEEDQ SKPLEVTVNS GGVVFFALFN SSSSEDASRK EEAAVIKFAS SRMATQSERL
201: GYEFSKWLGV QIPQARVIHS CNPEWTLIKE ATEKAQAKAT SEGDEVGEMT CSELLEALEL SRCLLLMSYV HGCPMLESMS SFETEEKAER AAAALGRILV
301: LDLVIRNEDR LPCRQLRWRG NPANLLLTDR IVSSAKHHEC SFDEAFDSAI KRYHPKDYRS IQRERRASSV DSRSRLSISD QMLVSQASDF SDITESPRSY
401: DTGLMSPMSD RSVAADFHLV AIDSGVPRRP PAGKRASDQE IYPRLVELLL NSSQYSSNLL HEITEGSLGY PQAEDGEETS NVRSVVTPVV REFRNGFRAG
501: LRDLQEFHIF LVTLHQKLDV LLRAFFSMMD KTMCADFDRE DFAVPESPSH THGHEVNHYP SPSKDRVPSD NSSDHSESDM QKSVPRTPNS ENKEDGSSPK
601: SRESWHGRSG KGGESLSSQR LAAKLRDFHK FAKVDAESNK ELDQWNETLR NEVMKLCQEN GFNTGFFEGS DNNSCTDAYE LKVRLEHILE RISLISKAAN
701: TEKPSMIQEN LFIGGGLAAR SIYTLQHLGI THVLCLCANE IGQSDTQYPD LFEYQNFSIT DDEDSNIESI FQEALDFIKH GEETGGKILV HCFEGRSRSA
801: TVVLAYLMLQ KKLTLLEAWS KLRKVHRRAQ PNDGFARILI NLDKKCHGKV SMEWRQRKPT MKVCPVCGKN AGLSSSSLKL HLQKSHRKLS SGSVDSAMNM
901: EIQKALEALK LSTGRGSSAS SNSFQSHPG
See Also
Citation
If you find this resource useful please cite one of the following publications:

Hooper CM, Castleden I, Tanz SK, Aryamanesh, and Millar, AH (2017) SUBA4: the interactive data analysis centre for Arabidopsis subcellular protein locations Nucleic Acids Res. Jan 4;45(D1):D1064-D1074. doi: 10.1093/nar/gkw1041 (PubMed)

Hooper CM, Tanz SK, Castleden IR, Vacher MA, Small ID, Millar AH (2014) "SUBAcon: a consensus algorithm for unifying the subcellular localization data of the Arabidopsis proteome. Bioinformatics." 1;30(23):3356-64. (Bioinformatics) (PubMed)