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AT5G22770.1
Subcellular Consensus
(Prediction and Experimental)
min: heatmap :max

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SUBAcon:
plasma membrane 1.000
ASURE: plasma membrane
What is SUBAcon?
Experimental Localisations and PPI
FP MS/MS PPI
  • PMID:31818904 (2020): mitochondrion
  • PMID:31520498 (2020): mitochondrion
  • PMID:30447334 (2019): plasma membrane
  • PMID:27177187 (2016): nucleus
  • PMID:26781341 (2016): plasma membrane
  • PMID:25900983 (2015): Golgi
  • PMID:25900983 (2015): Golgi trans-Golgi network early endosome
  • PMID:25900983 (2015): Golgi trans-Golgi network multivesicular body
  • PMID:22550958 (2012): plastid
  • PMID:21433285 (2011): plasma membrane
  • PMID:20843791 (2010): plasma membrane
  • PMID:19334764 (2009): plasma membrane
  • PMID:17317660 (2007): plasma membrane
SUBAcon links
AGI-AGI relationships
Coexpression PPI
Description (TAIR10) protein_coding : alpha-adaptin
Curator
Summary (TAIR10)
Computational
Description (TAIR10)
alpha-adaptin (alpha-ADR); FUNCTIONS IN: protein transporter activity, binding; INVOLVED IN: intracellular protein transport, vesicle-mediated transport, protein transport; LOCATED IN: plasma membrane, membrane; EXPRESSED IN: male gametophyte, pollen tube, leaf; EXPRESSED DURING: M germinated pollen stage; CONTAINS InterPro DOMAIN/s: Clathrin adaptor, alpha/beta/gamma-adaptin, appendage, Ig-like subdomain (InterPro:IPR008152), Adaptor protein complex AP-2, alpha subunit (InterPro:IPR017104), Armadillo-like helical (InterPro:IPR011989), Clathrin adaptor, alpha-adaptin, appendage, Ig-like subdomain (InterPro:IPR013038), Clathrin/coatomer adaptor, adaptin-like, N-terminal (InterPro:IPR002553), Clathrin adaptor, alpha-adaptin, appendage, C-terminal subdomain (InterPro:IPR003164), Armadillo-type fold (InterPro:IPR016024), Clathrin alpha-adaptin/coatomer adaptor, appendage, C-terminal subdomain (InterPro:IPR015873), Clathrin/coatomer adaptor, adaptin-like, appendage, C-terminal subdomain (InterPro:IPR009028), Clathrin/coatomer adaptor, adaptin-like, appendage, Ig-like subdomain (InterPro:IPR013041); BEST Arabidopsis thaliana protein match is: Adaptor protein complex AP-2, alpha subunit (TAIR:AT5G22780.1); Has 2529 Blast hits to 2470 proteins in 297 species: Archae - 0; Bacteria - 0; Metazoa - 987; Fungi - 687; Plants - 265; Viruses - 0; Other Eukaryotes - 590 (source: NCBI BLink).
Protein Annotations
BioGrid:17615eggNOG:ENOG410XNQEeggNOG:KOG1077EMBL:AB006699
EMBL:AB024030EMBL:AK318657EMBL:AK319011EMBL:AY099568
EMBL:CP002688EnsemblPlants:AT5G22770EnsemblPlants:AT5G22770.1EnsemblPlants:AT5G22770.2
EnsemblPlants:AT5G22770.3entrez:832340Gene3D:1.25.10.10Gene3D:2.60.40.1030
Gene3D:3.30.310.30GeneID:832340Genevisible:Q8LPL6GO:GO:0005886
GO:GO:0005905GO:GO:0006886GO:GO:0006897GO:GO:0008289
GO:GO:0008565GO:GO:0016020GO:GO:0030131hmmpanther:PTHR22780
hmmpanther:PTHR22780:SF4HOGENOM:HOG000170596InParanoid:Q8LPL6IntAct:Q8LPL6
InterPro:IPR002553InterPro:IPR003164InterPro:IPR008152InterPro:IPR009028
InterPro:IPR011989InterPro:IPR013038InterPro:IPR013041InterPro:IPR015873
InterPro:IPR016024InterPro:IPR017104iPTMnet:Q8LPL6KEGG:ath:AT5G22770
KO:K11824OMA:NPGCSPIPaxDb:Q8LPL6Pfam:PF01602
Pfam:PF02296Pfam:PF02883Pfam:Q8LPL6PhylomeDB:Q8LPL6
PIRSF:PIRSF037091PRIDE:Q8LPL6PRO:PR:Q8LPL6ProteinModelPortal:Q8LPL6
Proteomes:UP000006548RefSeq:NP_197669.1RefSeq:NP_851057.1RefSeq:NP_851058.1
SMART:SM00809SMR:Q8LPL6STRING:3702.AT5G22770.1SUPFAM:SSF48371
SUPFAM:SSF49348SUPFAM:SSF55711TAIR:AT5G22770tair10-symbols:alpha-ADR
UniGene:At.46641UniProt:Q8LPL6
Coordinates (TAIR10) chr5:-:7579844..7588026
Molecular Weight (calculated) 112156.00 Da
IEP (calculated) 6.14
GRAVY (calculated) -0.09
Length 1012 amino acids
Sequence (TAIR10)
(BLAST)
0001: MTGMRGLSVF ISDVRNCQNK EAERLRVDKE LGNIRTCFKN EKVLTPYKKK KYVWKMLYIH MLGYDVDFGH MEAVSLISAP KYPEKQVGYI VTSCLLNENH
0101: DFLKLAINTV RNDIIGRNET FQCLALTLVG NIGGRDFAES LAPDVQKLLI SSSCRPLVRK KAALCLLRLF RKNPDAVNVD GWADRMAQLL DERDLGVLTS
0201: STSLLVALVS NNHEAYSSCL PKCVKILERL ARNQDVPQEY TYYGIPSPWL QVKAMRALQY FPTIEDPSTR KALFEVLQRI LMGTDVVKNV NKNNASHAVL
0301: FEALSLVMHL DAEKEMMSQC VALLGKFISV REPNIRYLGL ENMTRMLMVT DVQDIIKKHQ SQIITSLKDP DISIRRRALD LLYGMCDVSN AKDIVEELLQ
0401: YLSTAEFSMR EELSLKAAIL AEKFAPDLSW YVDVILQLID KAGDFVSDDI WFRVVQFVTN NEDLQPYAAS KAREYLDKIA IHETMVKVSA YILGEYGHLL
0501: ARQPGCSASE LFSILHEKLP TISTPTIPIL LSTYAKLLMH AQPPDPELQK KVWAVFKKYE SCIDVEIQQR AVEYFELSKK GPAFMDVLAE MPKFPERQSS
0601: LIKKAENVED TADQSAIKLR AQQQPSNAMV LADQQPVNGA PPPLKVPILS GSTDPESVAR SLSHPNGTLS NIDPQTPSPD LLSDLLGPLA IEAPPGAVSN
0701: EQHGPVGAEG VPDEVDGSAI VPVEEQTNTV ELIGNIAERF HALCLKDSGV LYEDPHIQIG IKAEWRGHHG RLVLFMGNKN TSPLTSVQAL ILPPAHLRLD
0801: LSPVPDTIPP RAQVQSPLEV MNIRPSRDVA VLDFSYKFGA NVVSAKLRIP ATLNKFLQPL QLTSEEFFPQ WRAISGPPLK LQEVVRGVRP LALPEMANLF
0901: NSFHVTICPG LDPNPNNLVA STTFYSESTG AILCLARIET DPADRTQLRM TVGTGDPTLT FELKEFIKEQ LITVPMGSRA LVPAAGPAPP VAQPPSPAAL
1001: ADDPGAMLAG LL
See Also
Citation
If you find this resource useful please cite one of the following publications:

Hooper CM, Castleden I, Tanz SK, Aryamanesh, and Millar, AH (2017) SUBA4: the interactive data analysis centre for Arabidopsis subcellular protein locations Nucleic Acids Res. Jan 4;45(D1):D1064-D1074. doi: 10.1093/nar/gkw1041 (PubMed)

Hooper CM, Tanz SK, Castleden IR, Vacher MA, Small ID, Millar AH (2014) "SUBAcon: a consensus algorithm for unifying the subcellular localization data of the Arabidopsis proteome. Bioinformatics." 1;30(23):3356-64. (Bioinformatics) (PubMed)