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AT5G22000.1
Subcellular Consensus
(Prediction and Experimental)

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SUBAcon:
nucleus 1.000
What is SUBAcon?
What is ASURE?
SUBAcon computations
Experimental Localisations and PPI
FP MS/MS PPI
SUBAcon links
AGI-AGI relationships
Coexpression PPI
no PPI data
Description (TAIR10) protein_coding : RING-H2 group F2A
Curator
Summary (TAIR10)
encodes a RING-type E3 ubiquitin ligase implicated in gametogenesis. Double mutant analyses with RHF1a suggests that RHF2a may be involved in targetting ICK4KRP6 for degradation following meiosis in order to allow the mitoses associated with megagametogenesis and microgametogenesis to occur. RHF2a is expressed in all four floral whorls and is present at ~8-fold higher levels than RHF1a in inflorescences by RT-PCR analyses.
Computational
Description (TAIR10)
RING-H2 group F2A (RHF2A); FUNCTIONS IN: zinc ion binding; INVOLVED IN: regulation of cell cycle, proteolysis involved in cellular protein catabolic process, megagametogenesis, microgametogenesis; LOCATED IN: plasma membrane; EXPRESSED IN: 25 plant structures; EXPRESSED DURING: 15 growth stages; CONTAINS InterPro DOMAIN/s: Zinc finger, RING-type (InterPro:IPR001841), Zinc finger, C3HC4 RING-type (InterPro:IPR018957); BEST Arabidopsis thaliana protein match is: RING-H2 group F1A (TAIR:AT4G14220.1); Has 8011 Blast hits to 5867 proteins in 317 species: Archae - 0; Bacteria - 141; Metazoa - 1822; Fungi - 396; Plants - 2620; Viruses - 42; Other Eukaryotes - 2990 (source: NCBI BLink).
Protein Annotations
BioGrid:17535EC:6.3.2.-eggNOG:ENOG41121N2eggNOG:KOG0800EMBL:AF079182EMBL:AF324994EMBL:AK118336
EMBL:AK316835EMBL:AL589883EMBL:BT002347EMBL:CP002688EnsemblPlants:AT5G22000EnsemblPlants:AT5G22000.1EnsemblPlants:AT5G22000.3
entrez:832260Gene3D:3.30.40.10GeneID:832260Genevisible:Q9ZT42GO:GO:0005886GO:GO:0008270GO:GO:0009561
GO:GO:0016567GO:GO:0016874GO:GO:0051603GO:GO:0051726GO:GO:0055046hmmpanther:PTHR22763hmmpanther:PTHR22763:SF47
HOGENOM:HOG000070813InParanoid:Q9ZT42InterPro:IPR001841InterPro:IPR013083iPTMnet:Q9ZT42KEGG:ath:AT5G22000KO:K19043
OMA:QCILECQPaxDb:Q9ZT42Pfam:PF13639Pfam:Q9ZT42Pfscan:PS50089PhylomeDB:Q9ZT42PIR:T51854
PRIDE:Q9ZT42PRO:PR:Q9ZT42PROSITE:PS50089ProteinModelPortal:Q9ZT42Proteomes:UP000006548RefSeq:NP_568410.1RefSeq:NP_851050.1
RefSeq:NP_851051.1SMART:SM00184SMR:Q9ZT42STRING:3702.AT5G22000.1SUPFAM:SSF57850TAIR:AT5G22000tair10-symbols:RHF2A
UniGene:At.24118UniPathway:UPA00143UniProt:Q9ZT42
Coordinates (TAIR10) chr5:+:7277436..7279553
Molecular Weight (calculated) 41030.80 Da
IEP (calculated) 5.96
GRAVY (calculated) -0.86
Length 375 amino acids
Sequence (TAIR10)
(BLAST)
001: MEGAGETTTS EGHLTSAAAF VEGGIQDACD DACSICLESF CESDPSTLTS CKHEYHLQCI LEWCQRSSQC PMCWQSISLK DPTSQELLEA VEQERNFRFN
101: PTRNATIFRH PTLGDFELQH LPVGVDNAEI EERIIQHLAA AAAMGRARHG VRREGHRSRS SSQGHQQFMV FSSQPNASSP PPHPPMPSSP SQRDESDTVS
201: NLPHNALGEG SHQSNTQPPT SSHPRQVSPS ASDSNSRPLN QSSPSEQDRA GPSELQSFSE SLKSRLNAVS TRYKESISKN TRNWKDRLFS RNTSMADLGS
301: EVKREVSAGI ATVSRMMERL ETRENSRPST ASVSDVSENH TPETNNEHNR AAAGDEHSVN ERGVKETCAT GSGSS
See Also
Citation
If you find this resource useful please cite one of the following publications:

Hooper CM, Castleden I, Tanz SK, Aryamanesh, and Millar, AH (2017) SUBA4: the interactive data analysis centre for Arabidopsis subcellular protein locations Nucleic Acids Res. Jan 4;45(D1):D1064-D1074. doi: 10.1093/nar/gkw1041 (PubMed)

Hooper CM, Tanz SK, Castleden IR, Vacher MA, Small ID, Millar AH (2014) "SUBAcon: a consensus algorithm for unifying the subcellular localization data of the Arabidopsis proteome. Bioinformatics." 1;30(23):3356-64. (Bioinformatics) (PubMed)