suba logo
AT5G15410.1
Subcellular Consensus
(Prediction and Experimental)

min: heatmap :max

.
SUBAcon:
plasma membrane 1.000
What is SUBAcon?
What is ASURE?
SUBAcon computations
Experimental Localisations and PPI
FP MS/MS PPI
SUBAcon links
AGI-AGI relationships
Coexpression PPI
Description (TAIR10) protein_coding : Cyclic nucleotide-regulated ion channel family protein
Curator
Summary (TAIR10)
'defense, no death' gene (DND1) encodes a mutated cyclic nucleotide-gated cation channel; Same as CNGC2 (article ID 229): Cyclic nucleotide gated channel, activated by cAMP, conducts K+ and other monovalent cations but excludes Na+, does not contain the GYG amino acid sequence found in other channels with this conductivity profile. Conducts Ca2+ into cells which is linked to the generation of NO and the NO signaling pathway involved in the innate immune response to pathogens.
Computational
Description (TAIR10)
DEFENSE NO DEATH 1 (DND1); CONTAINS InterPro DOMAIN/s: Cyclic nucleotide-binding (InterPro:IPR000595), Cyclic nucleotide-binding-like (InterPro:IPR018490), RmlC-like jelly roll fold (InterPro:IPR014710); BEST Arabidopsis thaliana protein match is: cyclic nucleotide-gated cation channel 4 (TAIR:AT5G54250.2); Has 3052 Blast hits to 2968 proteins in 270 species: Archae - 0; Bacteria - 113; Metazoa - 1453; Fungi - 15; Plants - 978; Viruses - 0; Other Eukaryotes - 493 (source: NCBI BLink).
Protein Annotations
eggNOG:ENOG410XPSEeggNOG:KOG0498EMBL:AF067798EMBL:AF280939EMBL:AL391143EMBL:CP002688EMBL:Y16328
EnsemblPlants:AT5G15410EnsemblPlants:AT5G15410.1entrez:831393ExpressionAtlas:O65718Gene3D:2.60.120.10GeneID:831393Genevisible:O65718
GO:GO:0005221GO:GO:0005222GO:GO:0005242GO:GO:0005262GO:GO:0005516GO:GO:0005622GO:GO:0005886
GO:GO:0006952GO:GO:0007263GO:GO:0009626GO:GO:0016021GO:GO:0030552GO:GO:0030553GO:GO:0042391
GO:GO:0070588GO:GO:0071805GO:GO:0098655hmmpanther:PTHR10217hmmpanther:PTHR10217:SF501HOGENOM:HOG000238338InParanoid:O65718
InterPro:IPR000595InterPro:IPR005821InterPro:IPR014710InterPro:IPR018490KEGG:ath:AT5G15410KO:K05391OMA:TIHVIEN
PaxDb:O65718Pfam:O65718Pfam:PF00027Pfam:PF00520Pfscan:PS50042PhylomeDB:O65718PIR:T51519
PRO:PR:O65718PROSITE:PS50042ProteinModelPortal:O65718Proteomes:UP000006548Reactome:R-ATH-2485179Reactome:R-ATH-2514859Reactome:R-ATH-5620916
RefSeq:NP_197045.1SMART:SM00100SMR:O65718STRING:3702.AT5G15410.1SUPFAM:SSF51206SUPFAM:SSF81324TAIR:AT5G15410
tair10-symbols:ATCNGC2tair10-symbols:CNGC2tair10-symbols:DND1TCDB:1.A.1.5.6TMHMM:TMhelixUniGene:At.20813UniGene:At.74751
UniProt:O65718
Coordinates (TAIR10) chr5:-:5003460..5006763
Molecular Weight (calculated) 83245.90 Da
IEP (calculated) 9.98
GRAVY (calculated) -0.01
Length 726 amino acids
Sequence (TAIR10)
(BLAST)
001: MPSHPNFIFR WIGLFSDKFR RQTTGIDENS NLQINGGDSS SSGSDETPVL SSVECYACTQ VGVPAFHSTS CDQAHAPEWR ASAGSSLVPI QEGSVPNPAR
101: TRFRRLKGPF GEVLDPRSKR VQRWNRALLL ARGMALAVDP LFFYALSIGR TTGPACLYMD GAFAAVVTVL RTCLDAVHLW HVWLQFRLAY VSRESLVVGC
201: GKLVWDPRAI ASHYARSLTG FWFDVIVILP VPQAVFWLVV PKLIREEKVK LIMTILLLIF LFQFLPKIYH CICLMRRMQK VTGYIFGTIW WGFALNLIAY
301: FIASHVAGGC WYVLAIQRVA SCIRQQCMRT GNCNLSLACK EEVCYQFVSP TSTVGYPCLS GNLTSVVNKP MCLDSNGPFR YGIYRWALPV ISSNSLAVKI
401: LYPIFWGLMT LSTFANDLEP TSNWLEVIFS IVMVLSGLLL FTLLIGNIQV FLHAVMAKKR KMQIRCRDME WWMKRRQLPS RLRQRVRRFE RQRWNALGGE
501: DELELIHDLP PGLRRDIKRY LCFDLINKVP LFRGMDDLIL DNICDRAKPR VFSKDEKIIR EGDPVQRMIF IMRGRVKRIQ SLSKGVLATS TLEPGGYLGD
601: ELLSWCLRRP FLDRLPPSSA TFVCLENIEA FSLGSEDLRY ITDHFRYKFA NERLKRTARY YSSNWRTWAA VNIQMAWRRR RKRTRGENIG GSMSPVSENS
701: IEGNSERRLL QYAAMFMSIR PHDHLE
See Also
Citation
If you find this resource useful please cite one of the following publications:

Hooper CM, Castleden I, Tanz SK, Aryamanesh, and Millar, AH (2017) SUBA4: the interactive data analysis centre for Arabidopsis subcellular protein locations Nucleic Acids Res. Jan 4;45(D1):D1064-D1074. doi: 10.1093/nar/gkw1041 (PubMed)

Hooper CM, Tanz SK, Castleden IR, Vacher MA, Small ID, Millar AH (2014) "SUBAcon: a consensus algorithm for unifying the subcellular localization data of the Arabidopsis proteome. Bioinformatics." 1;30(23):3356-64. (Bioinformatics) (PubMed)