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AT5G14590.1
Subcellular Consensus
(Prediction and Experimental)

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SUBAcon:
mitochondrion 0.999
ASURE: mitochondrion
What is SUBAcon?
What is ASURE?
SUBAcon computations
Experimental Localisations and PPI
FP MS/MS PPI
SUBAcon links
AGI-AGI relationships
Coexpression PPI
no PPI data
Description (TAIR10) protein_coding : Isocitrate/isopropylmalate dehydrogenase family protein
Curator
Summary (TAIR10)
Computational
Description (TAIR10)
Isocitrate/isopropylmalate dehydrogenase family protein; FUNCTIONS IN: NAD or NADH binding, isocitrate dehydrogenase (NADP+) activity, magnesium ion binding, oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor; INVOLVED IN: oxidation reduction, isocitrate metabolic process, metabolic process; LOCATED IN: mitochondrion, chloroplast; EXPRESSED IN: 22 plant structures; EXPRESSED DURING: 14 growth stages; CONTAINS InterPro DOMAIN/s: Isocitrate/isopropylmalate dehydrogenase (InterPro:IPR001804), Isocitrate dehydrogenase NADP-dependent, eukaryotic (InterPro:IPR004790), Isocitrate/isopropylmalate dehydrogenase, conserved site (InterPro:IPR019818); BEST Arabidopsis thaliana protein match is: cytosolic NADP+-dependent isocitrate dehydrogenase (TAIR:AT1G65930.1); Has 30201 Blast hits to 17322 proteins in 780 species: Archae - 12; Bacteria - 1396; Metazoa - 17338; Fungi - 3422; Plants - 5037; Viruses - 0; Other Eukaryotes - 2996 (source: NCBI BLink).
Protein Annotations
BioCyc:ARA:AT5G14590-MONOMEREC:1.1.1.42eggNOG:COG0538eggNOG:KOG1526EMBL:AL163792EMBL:AY099683EMBL:BT000276
EMBL:CP002688EnsemblPlants:AT5G14590EnsemblPlants:AT5G14590.1entrez:831311Gene3D:3.40.718.10GeneID:831311Genevisible:Q8LPJ5
GO:GO:0000287GO:GO:0004450GO:GO:0005739GO:GO:0006099GO:GO:0006102GO:GO:0009507GO:GO:0009534
GO:GO:0009570GO:GO:0051287Gramene:AT5G14590.1gramene_pathway:1.1.1.42gramene_pathway:PWY-6549hmmpanther:PTHR11822hmmpanther:PTHR11822:SF5
HOGENOM:HOG000019858InParanoid:Q8LPJ5InterPro:IPR004790InterPro:IPR019818InterPro:IPR024084KEGG:00020+1.1.1.42KEGG:00480+1.1.1.42
KEGG:00720+1.1.1.42KEGG:ath:AT5G14590KO:K00031OMA:VMGMYNFPANTHER:PTHR11822PaxDb:Q8LPJ5Pfam:PF00180
Pfam:Q8LPJ5PhylomeDB:Q8LPJ5PIR:T48632PIRSF:PIRSF000108PRIDE:Q8LPJ5PRO:PR:Q8LPJ5PROSITE:PS00470
ProteinModelPortal:Q8LPJ5Proteomes:UP000006548Reactome:R-ATH-389542Reactome:R-ATH-71403RefSeq:NP_196963.2scanprosite:PS00470SMART:SM01329
SMR:Q8LPJ5STRING:3702.AT5G14590.1SUPFAM:SSF53659TAIR:AT5G14590TIGRfam:TIGR00127TIGRFAMs:TIGR00127UniGene:At.46811
UniProt:Q8LPJ5
Coordinates (TAIR10) chr5:-:4703533..4706627
Molecular Weight (calculated) 54199.10 Da
IEP (calculated) 8.12
GRAVY (calculated) -0.22
Length 485 amino acids
Sequence (TAIR10)
(BLAST)
001: MLNKLTHGVF TYRASLTAML SSSTSAGLSS SFVSSRFLSS GIFSSGASRN RVTFPVQFHR ASAVRCFASS GGSDRIQVQN PIVEMDGDEM TRVIWSMIKE
101: KLILPYLDLD IKYFDLGILN RDATDDKVTV ESAEAALKYN VAIKCATITP DEGRVKEFGL KSMWRSPNGT IRNILDGTVF REPIMCSNIP RLVPGWEKPI
201: CIGRHAFGDQ YRATDTVIKG PGKLKMVFVP EDGNAPVELD VYDFKGPGVA LAMYNVDESI RAFAESSMAM ALTKKWPLYL STKNTILKKY DGRFKDIFQE
301: VYEANWKQKF EEHSIWYEHR LIDDMVAYAV KSEGGYVWAC KNYDGDVQSD LLAQGFGSLG LMTSVLLSAD GKTLESEAAH GTVTRHFRLH QKGQETSTNS
401: IASIFAWTRG LEHRAKLDKN EKLMDFVKKL ESSCVNTVET GKMTKDLALL IHGPKVSRDL FLNTEEFIDA VASKLKTQFK ELPLV
See Also
Citation
If you find this resource useful please cite one of the following publications:

Hooper CM, Castleden I, Tanz SK, Aryamanesh, and Millar, AH (2017) SUBA4: the interactive data analysis centre for Arabidopsis subcellular protein locations Nucleic Acids Res. Jan 4;45(D1):D1064-D1074. doi: 10.1093/nar/gkw1041 (PubMed)

Hooper CM, Tanz SK, Castleden IR, Vacher MA, Small ID, Millar AH (2014) "SUBAcon: a consensus algorithm for unifying the subcellular localization data of the Arabidopsis proteome. Bioinformatics." 1;30(23):3356-64. (Bioinformatics) (PubMed)