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AT5G09230.1
Subcellular Consensus
(Prediction and Experimental)
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SUBAcon:
nucleus 1.000
ASURE: nucleus
What is SUBAcon?
Experimental Localisations and PPI
FP MS/MS PPI
SUBAcon links
AGI-AGI relationships
Coexpression PPI
no PPI data
Description (TAIR10) protein_coding : sirtuin 2
Curator
Summary (TAIR10)
Encodes SRT2, a member of the SIR2 (sirtuin) family HDAC (histone deacetylase) (SRT1/AT5g55760, SRT2/AT5G09230).
Computational
Description (TAIR10)
sirtuin 2 (SRT2); FUNCTIONS IN: NAD binding, DNA binding, zinc ion binding, hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides; INVOLVED IN: chromatin silencing, defense response to bacterium, negative regulation of defense response, regulation of transcription, DNA-dependent; LOCATED IN: chromatin silencing complex, nucleus; EXPRESSED IN: 23 plant structures; EXPRESSED DURING: 13 growth stages; CONTAINS InterPro DOMAIN/s: NAD-dependent histone deacetylase, silent information regulator Sir2 (InterPro:IPR003000); BEST Arabidopsis thaliana protein match is: sirtuin 1 (TAIR:AT5G55760.1); Has 30201 Blast hits to 17322 proteins in 780 species: Archae - 12; Bacteria - 1396; Metazoa - 17338; Fungi - 3422; Plants - 5037; Viruses - 0; Other Eukaryotes - 2996 (source: NCBI BLink).
Protein Annotations
BioGrid:16060EC:3.5.1.-eggNOG:COG0846eggNOG:KOG2683
EMBL:AK316908EMBL:AL391712EMBL:AY045873EMBL:AY122995
EMBL:CP002688EnsemblPlants:AT5G09230EnsemblPlants:AT5G09230.1EnsemblPlants:AT5G09230.2
EnsemblPlants:AT5G09230.7entrez:830782ExpressionAtlas:Q94AQ6Gene3D:3.30.1600.10
Gene3D:3.40.50.1220GeneID:830782Genevisible:Q94AQ6GO:GO:0005634
GO:GO:0005759GO:GO:0016787GO:GO:0046872GO:GO:0070403
HAMAP:MF_01967hmmpanther:PTHR11085hmmpanther:PTHR11085:SF6HOGENOM:HOG000085953
InParanoid:Q94AQ6InterPro:IPR003000InterPro:IPR026587InterPro:IPR026590
InterPro:IPR026591InterPro:IPR029035KEGG:ath:AT5G09230KO:K11414
OMA:EYVPHHKPANTHER:PTHR11085PaxDb:Q94AQ6Pfam:PF02146
Pfam:Q94AQ6Pfscan:PS50305PhylomeDB:Q94AQ6PRIDE:Q94AQ6
PRO:PR:Q94AQ6PROSITE:PS50305ProteinModelPortal:Q94AQ6Proteomes:UP000006548
RefSeq:NP_001078550.1RefSeq:NP_568207.1RefSeq:NP_850795.1RefSeq:NP_974753.1
SMR:Q94AQ6STRING:3702.AT5G09230.7SUPFAM:SSF52467TAIR:AT5G09230
tair10-symbols:AtSRT2tair10-symbols:SRT2UniGene:At.10037UniGene:At.70268
UniProt:Q94AQ6
Coordinates (TAIR10) chr5:+:2871655..2873613
Molecular Weight (calculated) 41537.90 Da
IEP (calculated) 9.08
GRAVY (calculated) -0.33
Length 373 amino acids
Sequence (TAIR10)
(BLAST)
001: MNMRRVFGGV STDLFPSRSM YRPLQSGGNL VMLFKGCRRF VRTTCRVSIP GGSLGNESKA PPRFLRDRKI VPDADPPNME DIHKLYRLFE QSSRLTILTG
101: AGVSTECGIP DYRSPNGAYS SGFKPITHQE FTRSSRARRR YWARSYAGWR RFTAAQPGPA HTALASLEKA GRINFMITQN VDRLHHRAGS DPLELHGTVY
201: TVMCLECGFS FPRDLFQDQL KAINPKWAEA IESIDHGDPG SEKSFGMKQR PDGDIEIDEK FWEEGFHIPV CEKCKGVLKP DVIFFGDNIP KERATQAMEV
301: AKQSDAFLVL GSSLMTMSAF RLCRAAHEAG AMTAIVNIGE TRADDIVPLK INARVGEILH RVLDVGSLSV PAL
See Also
Citation
If you find this resource useful please cite one of the following publications:

Hooper CM, Castleden I, Tanz SK, Aryamanesh, and Millar, AH (2017) SUBA4: the interactive data analysis centre for Arabidopsis subcellular protein locations Nucleic Acids Res. Jan 4;45(D1):D1064-D1074. doi: 10.1093/nar/gkw1041 (PubMed)

Hooper CM, Tanz SK, Castleden IR, Vacher MA, Small ID, Millar AH (2014) "SUBAcon: a consensus algorithm for unifying the subcellular localization data of the Arabidopsis proteome. Bioinformatics." 1;30(23):3356-64. (Bioinformatics) (PubMed)