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AT5G08280.1
Subcellular Consensus
(Prediction and Experimental)
min: heatmap :max

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SUBAcon:
plastid 1.000
ASURE: plastid
What is SUBAcon?
Experimental Localisations and PPI
FP MS/MS PPI
  • PMID:31932409 (2020): plastid
  • PMID:31871212 (2020): mitochondrion
  • PMID:31818904 (2020): mitochondrion
  • PMID:31615849 (2019): plastid plastid thylakoid
  • PMID:31520498 (2020): mitochondrion
  • PMID:31186290 (2019): plastid plastid stroma
  • PMID:30962257 (2019): plastid
  • PMID:30783145 (2019): extracellular region plant-type cell wall
  • PMID:30135097 (2018): plastid
  • PMID:29104584 (2017): nucleus nuclear matrix nucleolus
  • PMID:28865150 (2017): extracellular region plant-type cell wall
  • PMID:27137770 (2016): plastid plastid stroma
  • PMID:25900983 (2015): plant-type vacuole plant-type vacuole membrane
  • PMID:25900983 (2015): Golgi
  • PMID:25900983 (2015): Golgi Golgi apparatus Golgi membrane
  • PMID:25900983 (2015): Golgi trans-Golgi network
  • PMID:25900983 (2015): Golgi trans-Golgi network early endosome
  • PMID:25900983 (2015): Golgi trans-Golgi network multivesicular body
  • PMID:24872594 (2014): plastid plastid stroma
  • PMID:24361574 (2014): plastid plastid stroma
  • PMID:24124904 (2013): plastid
  • PMID:23851315 (2013): plastid
  • PMID:23673981 (2013): plastid plastid stroma plastoglobules
  • PMID:23549413 (2013): plastid plastid stroma
  • PMID:22550958 (2012): plastid
  • PMID:21531424 (2011): plastid
  • PMID:21311031 (2011): plastid
  • PMID:20423899 (2010): plastid
  • PMID:20061580 (2010): plastid plastid stroma
  • PMID:18633119 (2008): plastid plastid stroma
  • PMID:18431481 (2008): plastid plastid stroma
  • PMID:16207701 (2006): plastid
  • PMID:12938931 (2003): plastid
SUBAcon links
AGI-AGI relationships
Coexpression PPI
no PPI data
Description (TAIR10) protein_coding : hydroxymethylbilane synthase
Curator
Summary (TAIR10)
Encodes a protein with porphobilinogen deaminase activity. This protein is targeted to the chloroplast.
Computational
Description (TAIR10)
hydroxymethylbilane synthase (HEMC); FUNCTIONS IN: hydroxymethylbilane synthase activity; INVOLVED IN: chlorophyll biosynthetic process, defense response to bacterium, porphyrin biosynthetic process; LOCATED IN: apoplast, chloroplast, chloroplast stroma, chloroplast envelope; EXPRESSED IN: 23 plant structures; EXPRESSED DURING: 15 growth stages; CONTAINS InterPro DOMAIN/s: Porphobilinogen deaminase, dipyrromethane cofactor binding site (InterPro:IPR022419), Tetrapyrrole biosynthesis, hydroxymethylbilane synthase (InterPro:IPR000860), Porphobilinogen deaminase, N-terminal (InterPro:IPR022417), Porphobilinogen deaminase, C-terminal domain (InterPro:IPR022418); Has 7343 Blast hits to 7329 proteins in 2247 species: Archae - 198; Bacteria - 4150; Metazoa - 157; Fungi - 178; Plants - 78; Viruses - 0; Other Eukaryotes - 2582 (source: NCBI BLink).
Protein Annotations
BioCyc:ARA:AT5G08280-MONOMERBioCyc:MetaCyc:AT5G08280-MONOMERBioGrid:16002EC:2.5.1.61
eggNOG:COG0181eggNOG:KOG2892EMBL:AF419614EMBL:AL392174
EMBL:AY070431EMBL:AY087012EMBL:AY123037EMBL:CP002688
EMBL:X73535EMBL:X73839EnsemblPlants:AT5G08280EnsemblPlants:AT5G08280.1
entrez:830724Gene3D:3.30.160.40GeneID:830724Genevisible:Q43316
GO:GO:0004418GO:GO:0006782GO:GO:0009507GO:GO:0009570
GO:GO:0009941GO:GO:0015995GO:GO:0018160GO:GO:0042742
GO:GO:0048046Gramene:AT5G08280.1gramene_pathway:2.5.1.61gramene_pathway:PWY-5188
gramene_plant_reactome:4827054gramene_plant_reactome:6877122HAMAP:MF_00260hmmpanther:PTHR11557
hmmpanther:PTHR11557:SF0HOGENOM:HOG000228588InParanoid:Q43316InterPro:IPR000860
InterPro:IPR022417InterPro:IPR022418InterPro:IPR022419iPTMnet:Q43316
KEGG:00860+2.5.1.61KEGG:ath:AT5G08280KO:K01749MINT:MINT-8062098
OMA:GAICIESPANTHER:PTHR11557PaxDb:Q43316PDB:4HTG
PDBsum:4HTGPfam:PF01379Pfam:PF03900Pfam:Q43316
PhylomeDB:Q43316PIR:S50762PRIDE:Q43316PRINTS:PR00151
PRO:PR:Q43316PROSITE:PS00533ProteinModelPortal:Q43316Proteomes:UP000006548
Reactome:R-ATH-189451RefSeq:NP_196445.1scanprosite:PS00533SMR:Q43316
STRING:3702.AT5G08280.1SUPFAM:0047053SUPFAM:SSF53850SUPFAM:SSF54782
TAIR:AT5G08280tair10-symbols:HEMCTIGRfam:TIGR00212TIGRFAMs:TIGR00212
UniGene:At.48996UniGene:At.5343UniPathway:UPA00251UniPathway:UPA00668
UniProt:Q43316
Coordinates (TAIR10) chr5:-:2663763..2665596
Molecular Weight (calculated) 41045.70 Da
IEP (calculated) 8.63
GRAVY (calculated) -0.13
Length 382 amino acids
Sequence (TAIR10)
(BLAST)
001: MDIASSSLSQ AHKVVLTRQP SSRVNTCSLG SVSAIGFSLP QISSPALGKC RRKQSSSGFV KACVAVEQKT RTAIIRIGTR GSPLALAQAY ETREKLKKKH
101: PELVEDGAIH IEIIKTTGDK ILSQPLADIG GKGLFTKEID EALINGHIDI AVHSMKDVPT YLPEKTILPC NLPREDVRDA FICLTAATLA ELPAGSVVGT
201: ASLRRKSQIL HKYPALHVEE NFRGNVQTRL SKLQGGKVQA TLLALAGLKR LSMTENVASI LSLDEMLPAV AQGAIGIACR TDDDKMATYL ASLNHEETRL
301: AISCERAFLE TLDGSCRTPI AGYASKDEEG NCIFRGLVAS PDGTKVLETS RKGPYVYEDM VKMGKDAGQE LLSRAGPGFF GN
See Also
Citation
If you find this resource useful please cite one of the following publications:

Hooper CM, Castleden I, Tanz SK, Aryamanesh, and Millar, AH (2017) SUBA4: the interactive data analysis centre for Arabidopsis subcellular protein locations Nucleic Acids Res. Jan 4;45(D1):D1064-D1074. doi: 10.1093/nar/gkw1041 (PubMed)

Hooper CM, Tanz SK, Castleden IR, Vacher MA, Small ID, Millar AH (2014) "SUBAcon: a consensus algorithm for unifying the subcellular localization data of the Arabidopsis proteome. Bioinformatics." 1;30(23):3356-64. (Bioinformatics) (PubMed)