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AT5G05690.1
Subcellular Consensus
(Prediction and Experimental)

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SUBAcon:
endoplasmic reticulum 0.986
What is SUBAcon?
What is ASURE?
SUBAcon computations
Experimental Localisations and PPI
FP MS/MS PPI
SUBAcon links
AGI-AGI relationships
Coexpression PPI
no PPI data
Description (TAIR10) protein_coding : Cytochrome P450 superfamily protein
Curator
Summary (TAIR10)
Encodes a member of the CP90A family, a cytochrome P450 monooxygenase which converts 6-deoxocathasterone to 6-deoxoteasterone in the late C6 oxidation pathway and cathasterone to teasterone in the early C6 oxidation pathway of brassinolide biosynthesis. Expressed in cotyledons and leaves. Mutants display de-etiolation and derepression of light-induced genes in the dark, dwarfism, male sterility and activation of stress-regulated genes in the light. The expression of the gene using a CPD promoter:LUC fusion construct was shown to be under circadian and light control. Additionally, the circadian regulation was shown to be independent of BR levels as it remains unchanged in <i>bri1</i> mutant lines. CPD appears to be involved in the autonomous pathway that regulates the transition to flowering, primarily through a BRI1-mediated signaling pathway that affects FLC expression levels, as uncovered by double mutant analyses.
Computational
Description (TAIR10)
CONSTITUTIVE PHOTOMORPHOGENIC DWARF (CPD); FUNCTIONS IN: electron carrier activity, monooxygenase activity, iron ion binding, oxygen binding, heme binding; INVOLVED IN: in 9 processes; EXPRESSED IN: 23 plant structures; EXPRESSED DURING: 13 growth stages; CONTAINS InterPro DOMAIN/s: Cytochrome P450 (InterPro:IPR001128), Cytochrome P450, E-class, group I (InterPro:IPR002401), Cytochrome P450, conserved site (InterPro:IPR017972); BEST Arabidopsis thaliana protein match is: Cytochrome P450 superfamily protein (TAIR:AT3G50660.1); Has 1807 Blast hits to 1807 proteins in 277 species: Archae - 0; Bacteria - 0; Metazoa - 736; Fungi - 347; Plants - 385; Viruses - 0; Other Eukaryotes - 339 (source: NCBI BLink).
Protein Annotations
BioCyc:ARA:AT5G05690-MONOMERBioCyc:ARA:GQT-699-MONOMERBioCyc:ARA:GQT-700-MONOMERBioCyc:MetaCyc:AT5G05690-MONOMERBioGrid:15732EC:1.14.-.-eggNOG:COG2124
eggNOG:KOG0157EMBL:AB005237EMBL:AY042837EMBL:AY052726EMBL:AY063722EMBL:AY081480EMBL:AY087526
EMBL:CP002688EMBL:X87367EMBL:X87368EnsemblPlants:AT5G05690EnsemblPlants:AT5G05690.1entrez:830453ExpressionAtlas:Q42569
Gene3D:1.10.630.10GeneID:830453Genevisible:Q42569GO:GO:0004497GO:GO:0005506GO:GO:0009911GO:GO:0010224
GO:GO:0010268GO:GO:0010584GO:GO:0016021GO:GO:0016125GO:GO:0016132GO:GO:0016705GO:GO:0020037
GO:GO:0048657gramene_pathway:1.14.-.-gramene_pathway:PWY-2582gramene_pathway:PWY-699gramene_plant_reactome:1119456gramene_plant_reactome:6873965hmmpanther:PTHR24286
hmmpanther:PTHR24286:SF44HOGENOM:HOG000237614InParanoid:Q42569InterPro:IPR001128InterPro:IPR002401InterPro:IPR017972iPTMnet:Q42569
OMA:GERKNDMPaxDb:Q42569Pfam:PF00067Pfam:Q42569PhylomeDB:Q42569PIR:S55379PRIDE:Q42569
PRINTS:PR00385PRINTS:PR00463PRO:PR:Q42569PROSITE:PS00086ProteinModelPortal:Q42569Proteomes:UP000006548Reactome:R-ATH-211916
Reactome:R-ATH-5365859RefSeq:NP_196188.1scanprosite:PS00086SMR:Q42569STRING:3702.AT5G05690.1SUPFAM:SSF48264TAIR:AT5G05690
tair10-symbols:CBB3tair10-symbols:CPDtair10-symbols:CYP90tair10-symbols:CYP90Atair10-symbols:CYP90A1tair10-symbols:DWF3TMHMM:TMhelix
UniGene:At.20458UniProt:Q42569
Coordinates (TAIR10) chr5:-:1702907..1706705
Molecular Weight (calculated) 53788.50 Da
IEP (calculated) 9.46
GRAVY (calculated) -0.07
Length 472 amino acids
Sequence (TAIR10)
(BLAST)
001: MAFTAFLLLL SSIAAGFLLL LRRTRYRRMG LPPGSLGLPL IGETFQLIGA YKTENPEPFI DERVARYGSV FMTHLFGEPT IFSADPETNR FVLQNEGKLF
101: ECSYPASICN LLGKHSLLLM KGSLHKRMHS LTMSFANSSI IKDHLMLDID RLVRFNLDSW SSRVLLMEEA KKITFELTVK QLMSFDPGEW SESLRKEYLL
201: VIEGFFSLPL PLFSTTYRKA IQARRKVAEA LTVVVMKRRE EEEEGAERKK DMLAALLAAD DGFSDEEIVD FLVALLVAGY ETTSTIMTLA VKFLTETPLA
301: LAQLKEEHEK IRAMKSDSYS LEWSDYKSMP FTQCVVNETL RVANIIGGVF RRAMTDVEIK GYKIPKGWKV FSSFRAVHLD PNHFKDARTF NPWRWQSNSV
401: TTGPSNVFTP FGGGPRLCPG YELARVALSV FLHRLVTGFS WVPAEQDKLV FFPTTRTQKR YPIFVKRRDF AT
See Also
Citation
If you find this resource useful please cite one of the following publications:

Hooper CM, Castleden I, Tanz SK, Aryamanesh, and Millar, AH (2017) SUBA4: the interactive data analysis centre for Arabidopsis subcellular protein locations Nucleic Acids Res. Jan 4;45(D1):D1064-D1074. doi: 10.1093/nar/gkw1041 (PubMed)

Hooper CM, Tanz SK, Castleden IR, Vacher MA, Small ID, Millar AH (2014) "SUBAcon: a consensus algorithm for unifying the subcellular localization data of the Arabidopsis proteome. Bioinformatics." 1;30(23):3356-64. (Bioinformatics) (PubMed)