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AT4G37930.1
Subcellular Consensus
(Prediction and Experimental)

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SUBAcon:
mitochondrion 1.000
What is SUBAcon?
What is ASURE?
SUBAcon computations
Experimental Localisations and PPI
FP MS/MS PPI
SUBAcon links
AGI-AGI relationships
Coexpression PPI
Description (TAIR10) protein_coding : serine transhydroxymethyltransferase 1
Curator
Summary (TAIR10)
Encodes a protein with mitochondrial serine hydroxymethyltransferase activity, which functions in the photorespiratory pathway, catalyzes the conversion of serine and tetrahydrofolate to glycine and 5,10-methylene tetrahydrofolate. Involved in controlling cell damage caused by abiotic stress, such as high light and salt and the hypersensitive defense response of plants.
Computational
Description (TAIR10)
serine transhydroxymethyltransferase 1 (SHM1); FUNCTIONS IN: poly(U) RNA binding, glycine hydroxymethyltransferase activity; INVOLVED IN: in 8 processes; LOCATED IN: in 9 components; EXPRESSED IN: 28 plant structures; EXPRESSED DURING: 17 growth stages; CONTAINS InterPro DOMAIN/s: Pyridoxal phosphate-dependent transferase, major domain (InterPro:IPR015424), Serine hydroxymethyltransferase, pyridoxal phosphate binding site (InterPro:IPR019798), Pyridoxal phosphate-dependent transferase, major region, subdomain 1 (InterPro:IPR015421), Serine hydroxymethyltransferase (InterPro:IPR001085); BEST Arabidopsis thaliana protein match is: serine hydroxymethyltransferase 2 (TAIR:AT5G26780.1); Has 11621 Blast hits to 11596 proteins in 2825 species: Archae - 258; Bacteria - 6371; Metazoa - 337; Fungi - 287; Plants - 346; Viruses - 6; Other Eukaryotes - 4016 (source: NCBI BLink).
Protein Annotations
BioCyc:ARA:AT4G37930-MONOMERBioCyc:MetaCyc:AT4G37930-MONOMERBioGrid:15230EC:2.1.2.1eggNOG:COG0112eggNOG:KOG2467EMBL:AF428388
EMBL:AJ271726EMBL:AL035538EMBL:AL161592EMBL:AY054254EMBL:AY057645EMBL:AY070726EMBL:BT006353
EMBL:CP002687EnsemblPlants:AT4G37930EnsemblPlants:AT4G37930.1entrez:829949Gene3D:3.40.640.10Gene3D:3.90.1150.10GeneID:829949
Genevisible:Q9SZJ5GO:GO:0004372GO:GO:0005634GO:GO:0005739GO:GO:0005759GO:GO:0005829GO:GO:0005886
GO:GO:0006544GO:GO:0006563GO:GO:0007623GO:GO:0008266GO:GO:0009409GO:GO:0009416GO:GO:0009507
GO:GO:0009534GO:GO:0009570GO:GO:0009626GO:GO:0009853GO:GO:0010319GO:GO:0016020GO:GO:0022626
GO:GO:0030170GO:GO:0035999GO:GO:0046686GO:GO:0048046Gramene:AT4G37930.1gramene_pathway:2.1.2.1gramene_pathway:GLYSYN2-PWY
gramene_pathway:PWY-181gramene_pathway:PWY-2161gramene_pathway:PWY-2201gramene_pathway:PWY-3841gramene_plant_reactome:1119311gramene_plant_reactome:1119617gramene_plant_reactome:6876322
gramene_plant_reactome:6876934HAMAP:MF_00051hmmpanther:PTHR11680hmmpanther:PTHR11680:SF10HOGENOM:HOG000239405InParanoid:Q9SZJ5IntAct:Q9SZJ5
InterPro:IPR001085InterPro:IPR015421InterPro:IPR015422InterPro:IPR015424InterPro:IPR019798iPTMnet:Q9SZJ5KEGG:00260+2.1.2.1
KEGG:00460+2.1.2.1KEGG:00630+2.1.2.1KEGG:00670+2.1.2.1KEGG:00680+2.1.2.1KEGG:ath:AT4G37930KO:K00600OMA:MTIANYD
PANTHER:PTHR11680PaxDb:Q9SZJ5Pfam:PF00464Pfam:Q9SZJ5PhylomeDB:Q9SZJ5PIR:T05620PIRSF:PIRSF000412
PRIDE:Q9SZJ5PRO:PR:Q9SZJ5PROSITE:PS00096ProteinModelPortal:Q9SZJ5Proteomes:UP000006548Reactome:R-ATH-196757Reactome:R-ATH-71262
RefSeq:NP_195506.1scanprosite:PS00096SMR:Q9SZJ5STRING:3702.AT4G37930.1SUPFAM:SSF53383TAIR:AT4G37930tair10-symbols:SHM1
tair10-symbols:SHMT1tair10-symbols:STMUniGene:At.21766UniPathway:UPA00193unipathway:UPA00288UniProt:Q9SZJ5
Coordinates (TAIR10) chr4:-:17831891..17834742
Molecular Weight (calculated) 57403.90 Da
IEP (calculated) 8.37
GRAVY (calculated) -0.33
Length 517 amino acids
Sequence (TAIR10)
(BLAST)
001: MAMAMALRRL SSSIDKPIRP LIRSTSCYMS SLPSEAVDEK ERSRVTWPKQ LNAPLEEVDP EIADIIEHEK ARQWKGLELI PSENFTSVSV MQAVGSVMTN
101: KYSEGYPGAR YYGGNEYIDM AETLCQKRAL EAFRLDPEKW GVNVQPLSGS PANFHVYTAL LKPHERIMAL DLPHGGHLSH GYQTDTKKIS AVSIFFETMP
201: YRLDESTGYI DYDQMEKSAT LFRPKLIVAG ASAYARLYDY ARIRKVCNKQ KAVMLADMAH ISGLVAANVI PSPFDYADVV TTTTHKSLRG PRGAMIFFRK
301: GVKEINKQGK EVLYDFEDKI NQAVFPGLQG GPHNHTITGL AVALKQATTS EYKAYQEQVL SNSAKFAQTL MERGYELVSG GTDNHLVLVN LKPKGIDGSR
401: VEKVLEAVHI ASNKNTVPGD VSAMVPGGIR MGTPALTSRG FVEEDFAKVA EYFDKAVTIA LKVKSEAQGT KLKDFVSAME SSSTIQSEIA KLRHEVEEFA
501: KQFPTIGFEK ETMKYKN
See Also
Citation
If you find this resource useful please cite one of the following publications:

Hooper CM, Castleden I, Tanz SK, Aryamanesh, and Millar, AH (2017) SUBA4: the interactive data analysis centre for Arabidopsis subcellular protein locations Nucleic Acids Res. Jan 4;45(D1):D1064-D1074. doi: 10.1093/nar/gkw1041 (PubMed)

Hooper CM, Tanz SK, Castleden IR, Vacher MA, Small ID, Millar AH (2014) "SUBAcon: a consensus algorithm for unifying the subcellular localization data of the Arabidopsis proteome. Bioinformatics." 1;30(23):3356-64. (Bioinformatics) (PubMed)