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AT4G35800.1
Subcellular Consensus
(Prediction and Experimental)

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SUBAcon:
nucleus 1.000
ASURE: nucleus
What is SUBAcon?
What is ASURE?
SUBAcon computations
Experimental Localisations and PPI
FP MS/MS PPI
  • PMID:25900983 (2015): Golgi
  • PMID:25900983 (2015): Golgi trans-Golgi network early endosome
  • PMID:23396599 (2013): nucleus nuclear envelope nuclear inner membrane
  • PMID:15028209 (2004): plastid
SUBAcon links
AGI-AGI relationships
Coexpression PPI
Description (TAIR10) protein_coding : RNA polymerase II large subunit
Curator
Summary (TAIR10)
Encodes the unique largest subunit of nuclear DNA-dependent RNA polymerase II; the ortholog of budding yeast RPB1 and a homolog of the E. coli RNA polymerase beta prime subunit.
Computational
Description (TAIR10)
RNA polymerase II large subunit (NRPB1); FUNCTIONS IN: DNA-directed RNA polymerase activity, DNA binding; INVOLVED IN: transcription, transcription from RNA polymerase II promoter; LOCATED IN: nucleus, chloroplast, DNA-directed RNA polymerase II, core complex, vacuole; EXPRESSED IN: 26 plant structures; EXPRESSED DURING: 15 growth stages; CONTAINS InterPro DOMAIN/s: RNA polymerase, N-terminal (InterPro:IPR006592), RNA polymerase, alpha subunit (InterPro:IPR000722), RNA polymerase II, heptapeptide repeat, eukaryotic (InterPro:IPR000684), RNA polymerase Rpb1, domain 7 (InterPro:IPR007073), RNA polymerase Rpb1, domain 3 (InterPro:IPR007066), RNA polymerase Rpb1, domain 1 (InterPro:IPR007080), RNA polymerase Rpb1, domain 4 (InterPro:IPR007083), RNA polymerase Rpb1, domain 5 (InterPro:IPR007081), RNA polymerase Rpb1, domain 6 (InterPro:IPR007075); BEST Arabidopsis thaliana protein match is: nuclear RNA polymerase C1 (TAIR:AT5G60040.1); Has 181834 Blast hits to 82224 proteins in 9254 species: Archae - 731; Bacteria - 33255; Metazoa - 56600; Fungi - 34284; Plants - 19037; Viruses - 3576; Other Eukaryotes - 34351 (source: NCBI BLink).
Protein Annotations
BioCyc:ARA:AT4G35800-MONOMERBioGrid:15016DIP:DIP-40008NEC:2.7.7.6eggNOG:COG0086eggNOG:KOG0260EMBL:AK221166
EMBL:AL031986EMBL:AL161588EMBL:CP002687EMBL:X52494EMBL:X52954EnsemblPlants:AT4G35800EnsemblPlants:AT4G35800.1
entrez:829734GeneID:829734Genevisible:P18616GO:GO:0003677GO:GO:0003899GO:GO:0005665GO:GO:0006366
GO:GO:0046872Gramene:AT4G35800.1hmmpanther:PTHR19376hmmpanther:PTHR19376:SF37HOGENOM:HOG000222975InParanoid:P18616IntAct:P18616
InterPro:IPR000684InterPro:IPR000722InterPro:IPR006592InterPro:IPR007066InterPro:IPR007073InterPro:IPR007075InterPro:IPR007080
InterPro:IPR007081InterPro:IPR007083iPTMnet:P18616KEGG:00230+2.7.7.6KEGG:00240+2.7.7.6KEGG:ath:AT4G35800KO:K03006
ncoils:CoilOMA:TGDNSWPPaxDb:P18616Pfam:P18616Pfam:PF00623Pfam:PF04983Pfam:PF04990
Pfam:PF04992Pfam:PF04997Pfam:PF04998Pfam:PF05000Pfam:PF05001PhylomeDB:P18616PIR:G85422
PIR:T04690PRIDE:P18616PRO:PR:P18616PROSITE:PS00115ProteinModelPortal:P18616Proteomes:UP000006548Reactome:R-ATH-112382
Reactome:R-ATH-113418Reactome:R-ATH-674695Reactome:R-ATH-6781823Reactome:R-ATH-6782135Reactome:R-ATH-6782210Reactome:R-ATH-72086Reactome:R-ATH-72163
Reactome:R-ATH-72165Reactome:R-ATH-72203Reactome:R-ATH-73776Reactome:R-ATH-73779Reactome:R-ATH-75953Reactome:R-ATH-76042Reactome:R-ATH-77075
RefSeq:NP_195305.2scanprosite:PS00115SMART:SM00663STRING:3702.AT4G35800.1SUPFAM:SSF64484TAIR:AT4G35800tair10-symbols:NRPB1
tair10-symbols:RNA_POL_II_LStair10-symbols:RNA_POL_II_LSRNA_POL_II_LStair10-symbols:RPB1UniGene:At.23499UniGene:At.67132UniProt:P18616
Coordinates (TAIR10) chr4:-:16961115..16967892
Molecular Weight (calculated) 204637.00 Da
IEP (calculated) 5.87
GRAVY (calculated) -0.52
Length 1839 amino acids
Sequence (TAIR10)
(BLAST)
0001: MDTRFPFSPA EVSKVRVVQF GILSPDEIRQ MSVIHVEHSE TTEKGKPKVG GLSDTRLGTI DRKVKCETCM ANMAECPGHF GYLELAKPMY HVGFMKTVLS
0101: IMRCVCFNCS KILADEEEHK FKQAMKIKNP KNRLKKILDA CKNKTKCDGG DDIDDVQSHS TDEPVKKSRG GCGAQQPKLT IEGMKMIAEY KIQRKKNDEP
0201: DQLPEPAERK QTLGADRVLS VLKRISDADC QLLGFNPKFA RPDWMILEVL PIPPPPVRPS VMMDATSRSE DDLTHQLAMI IRHNENLKRQ EKNGAPAHII
0301: SEFTQLLQFH IATYFDNELP GQPRATQKSG RPIKSICSRL KAKEGRIRGN LMGKRVDFSA RTVITPDPTI NIDELGVPWS IALNLTYPET VTPYNIERLK
0401: ELVDYGPHPP PGKTGAKYII RDDGQRLDLR YLKKSSDQHL ELGYKVERHL QDGDFVLFNR QPSLHKMSIM GHRIRIMPYS TFRLNLSVTS PYNADFDGDE
0501: MNMHVPQSFE TRAEVLELMM VPKCIVSPQA NRPVMGIVQD TLLGCRKITK RDTFIEKDVF MNTLMWWEDF DGKVPAPAIL KPRPLWTGKQ VFNLIIPKQI
0601: NLLRYSAWHA DTETGFITPG DTQVRIERGE LLAGTLCKKT LGTSNGSLVH VIWEEVGPDA ARKFLGHTQW LVNYWLLQNG FTIGIGDTIA DSSTMEKINE
0701: TISNAKTAVK DLIRQFQGKE LDPEPGRTMR DTFENRVNQV LNKARDDAGS SAQKSLAETN NLKAMVTAGS KGSFINISQM TACVGQQNVE GKRIPFGFDG
0801: RTLPHFTKDD YGPESRGFVE NSYLRGLTPQ EFFFHAMGGR EGLIDTAVKT SETGYIQRRL VKAMEDIMVK YDGTVRNSLG DVIQFLYGED GMDAVWIESQ
0901: KLDSLKMKKS EFDRTFKYEI DDENWNPTYL SDEHLEDLKG IRELRDVFDA EYSKLETDRF QLGTEIATNG DSTWPLPVNI KRHIWNAQKT FKIDLRKISD
1001: MHPVEIVDAV DKLQERLLVV PGDDALSVEA QKNATLFFNI LLRSTLASKR VLEEYKLSRE AFEWVIGEIE SRFLQSLVAP GEMIGCVAAQ SIGEPATQMT
1101: LNTFHYAGVS AKNVTLGVPR LREIINVAKR IKTPSLSVYL TPEASKSKEG AKTVQCALEY TTLRSVTQAT EVWYDPDPMS TIIEEDFEFV RSYYEMPDED
1201: VSPDKISPWL LRIELNREMM VDKKLSMADI AEKINLEFDD DLTCIFNDDN AQKLILRIRI MNDEGPKGEL QDESAEDDVF LKKIESNMLT EMALRGIPDI
1301: NKVFIKQVRK SRFDEEGGFK TSEEWMLDTE GVNLLAVMCH EDVDPKRTTS NHLIEIIEVL GIEAVRRALL DELRVVISFD GSYVNYRHLA ILCDTMTYRG
1401: HLMAITRHGI NRNDTGPLMR CSFEETVDIL LDAAAYAETD CLRGVTENIM LGQLAPIGTG DCELYLNDEM LKNAIELQLP SYMDGLEFGM TPARSPVSGT
1501: PYHEGMMSPN YLLSPNMRLS PMSDAQFSPY VGGMAFSPSS SPGYSPSSPG YSPTSPGYSP TSPGYSPTSP GYSPTSPTYS PSSPGYSPTS PAYSPTSPSY
1601: SPTSPSYSPT SPSYSPTSPS YSPTSPSYSP TSPSYSPTSP AYSPTSPAYS PTSPAYSPTS PSYSPTSPSY SPTSPSYSPT SPSYSPTSPS YSPTSPAYSP
1701: TSPGYSPTSP SYSPTSPSYG PTSPSYNPQS AKYSPSIAYS PSNARLSPAS PYSPTSPNYS PTSPSYSPTS PSYSPSSPTY SPSSPYSSGA SPDYSPSAGY
1801: SPTLPGYSPS STGQYTPHEG DKKDKTGKKD ASKDDKGNP
See Also
Citation
If you find this resource useful please cite one of the following publications:

Hooper CM, Castleden I, Tanz SK, Aryamanesh, and Millar, AH (2017) SUBA4: the interactive data analysis centre for Arabidopsis subcellular protein locations Nucleic Acids Res. Jan 4;45(D1):D1064-D1074. doi: 10.1093/nar/gkw1041 (PubMed)

Hooper CM, Tanz SK, Castleden IR, Vacher MA, Small ID, Millar AH (2014) "SUBAcon: a consensus algorithm for unifying the subcellular localization data of the Arabidopsis proteome. Bioinformatics." 1;30(23):3356-64. (Bioinformatics) (PubMed)