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AT4G34650.1
Subcellular Consensus
(Prediction and Experimental)
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SUBAcon:
endoplasmic reticulum 1.000
What is SUBAcon?
Experimental Localisations and PPI
FP MS/MS PPI
  • PMID:18236008 (2008): endoplasmic reticulum
SUBAcon links
AGI-AGI relationships
Coexpression PPI
no PPI data
Description (TAIR10) protein_coding : squalene synthase 2
Curator
Summary (TAIR10)
Encodes a protein with similarity to squalene synthase which catalyzes the first committed step in sterol biosynthesis. To date no experimental evidence exists that SQS2 functions as a squalene synthase and some experiments indicate it does not have this function.
Computational
Description (TAIR10)
squalene synthase 2 (SQS2); FUNCTIONS IN: farnesyl-diphosphate farnesyltransferase activity; INVOLVED IN: N-terminal protein myristoylation, sterol biosynthetic process; LOCATED IN: integral to membrane; EXPRESSED IN: 9 plant structures; EXPRESSED DURING: 4 anthesis, petal differentiation and expansion stage; CONTAINS InterPro DOMAIN/s: Terpenoid synthase (InterPro:IPR008949), Farnesyl-diphosphate farnesyltransferase (InterPro:IPR006449), Squalene/phytoene synthase (InterPro:IPR002060); BEST Arabidopsis thaliana protein match is: squalene synthase 1 (TAIR:AT4G34640.1); Has 1176 Blast hits to 1175 proteins in 496 species: Archae - 34; Bacteria - 579; Metazoa - 114; Fungi - 168; Plants - 163; Viruses - 0; Other Eukaryotes - 118 (source: NCBI BLink).
Protein Annotations
eggNOG:COG1562eggNOG:KOG1459EMBL:AL023094EMBL:AL161585
EMBL:CP002687EnsemblPlants:AT4G34650EnsemblPlants:AT4G34650.1entrez:829617
Gene3D:1.10.600.10GeneID:829617GO:GO:0004310GO:GO:0016021
GO:GO:0016126Gramene:AT4G34650.1gramene_pathway:2.5.1.21gramene_pathway:PWY-5670
gramene_plant_reactome:1119370gramene_plant_reactome:6873791gramene_plant_reactome:6875407hmmpanther:PTHR11626
hmmpanther:PTHR11626:SF2InterPro:IPR002060InterPro:IPR006449InterPro:IPR008949
KEGG:00100+2.5.1.21KEGG:00909+2.5.1.21KEGG:ath:AT4G34650KO:K00801
OMA:VNDETQSPfam:PF00494PhylomeDB:O65688PIR:E85408
PIR:T05285Proteomes:UP000006548Reactome:R-ATH-191273RefSeq:NP_195191.2
SMR:O65688STRING:3702.AT4G34650.1SUPFAM:SSF48576TAIR:AT4G34650
tair10-symbols:SQS2TIGRfam:TIGR01559TIGRFAMs:TIGR01559TMHMM:TMhelix
UniGene:At.54604unipathway:UPA00767UniProt:O65688
Coordinates (TAIR10) chr4:+:16542377..16544915
Molecular Weight (calculated) 47185.70 Da
IEP (calculated) 8.01
GRAVY (calculated) -0.05
Length 413 amino acids
Sequence (TAIR10)
(BLAST)
001: MGSLSTILRH PDELYPLLKL KLAITKAQKQ IPLEPHLAFC YSILHKVSKS FSLVIQQLGT ELRNAVCVFY LILRALDTVE DDTSVPVEIK VPILIAFHRH
101: IYDGDWHFSC GTKEYKLLMD QFHHVSAAFL KLEKGYQEAI EDITKRMGAG MAKFICKEVE TIDDYDEYCH YAAGLVGLGL SKIFIASELE ILTPDWKQIS
201: NSTGLFLQKT NIIKDYLEDI NERPKSRMFW PREIWGKYVD KLEDFKNEEK ATKAVQCLNE MVTNALNHVE DCLKSLASLR DPAIFQSCAI PQIVAIGTLA
301: LCYNNVQVFR GVVRLRRGLI AKVIDRTKTM DDVYGAFYDF SCMLQTKVDN NDPNAMKTLN RLETIKKFCK ENGGLHKRKS YVNDETQSKA IFVVMFVLLL
401: AIVVVYLKAN QCK
See Also
Citation
If you find this resource useful please cite one of the following publications:

Hooper CM, Castleden I, Tanz SK, Aryamanesh, and Millar, AH (2017) SUBA4: the interactive data analysis centre for Arabidopsis subcellular protein locations Nucleic Acids Res. Jan 4;45(D1):D1064-D1074. doi: 10.1093/nar/gkw1041 (PubMed)

Hooper CM, Tanz SK, Castleden IR, Vacher MA, Small ID, Millar AH (2014) "SUBAcon: a consensus algorithm for unifying the subcellular localization data of the Arabidopsis proteome. Bioinformatics." 1;30(23):3356-64. (Bioinformatics) (PubMed)