AT4G34580.1
|
Subcellular Consensus
(Prediction and Experimental) min:  :max.
SUBAcon:plasma membrane 1.000 What is SUBAcon? |
|||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Experimental Localisations and PPI |
|
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
|
SUBAcon links
AGI-AGI relationships |
|
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Description (TAIR10) | protein_coding : Sec14p-like phosphatidylinositol transfer family protein | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Curator Summary (TAIR10) |
Encodes COW1 (can of worms1), a phosphatidylinositol transfer protein essential for root hair tip growth. The N-terminus of the COW1 protein is 32% identical to an essential phosphatidylinositol transfer protein (PITP), the yeast Sec14 protein (sec14p) while the C-terminus is 34.5% identical to a late nodulin of Lotus japonicus, Nlj16. Expression of COW1 complements the growth defect associated with Sec14p dysfunction in yeast. GFP fused to the COW1 protein specifically accumulates at the site of root hair outgrowth. | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Computational Description (TAIR10) |
CAN OF WORMS1 (COW1); FUNCTIONS IN: transporter activity, phosphatidylinositol transporter activity; INVOLVED IN: root epidermal cell differentiation, transport, root hair cell tip growth, cell tip growth; LOCATED IN: intracellular; EXPRESSED IN: 9 plant structures; CONTAINS InterPro DOMAIN/s: Cellular retinaldehyde-binding/triple function, C-terminal (InterPro:IPR001251), Cellular retinaldehyde-binding/triple function, N-terminal (InterPro:IPR008273), Cellular retinaldehyde binding/alpha-tocopherol transport (InterPro:IPR001071), Phosphatidylinositol transfer protein-like, N-terminal (InterPro:IPR011074); BEST Arabidopsis thaliana protein match is: Sec14p-like phosphatidylinositol transfer family protein (TAIR:AT2G16380.1); Has 3006 Blast hits to 2988 proteins in 244 species: Archae - 0; Bacteria - 0; Metazoa - 982; Fungi - 671; Plants - 907; Viruses - 0; Other Eukaryotes - 446 (source: NCBI BLink). | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Protein Annotations |
|
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Coordinates (TAIR10) | chr4:+:16515422..16518527 | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Molecular Weight (calculated) | 63290.40 Da | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| IEP (calculated) | 8.43 | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| GRAVY (calculated) | -0.53 | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Length | 554 amino acids | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Sequence (TAIR10) (BLAST) |
001: MAETKPEIEM SEEERKIVKI SSLKKKAINA SNRFKNSFKK KGRRSSSRVM SVPIEDDIDA EDLQALDAFR QALILDELLP SKLDDLHMML RFLRARKFDI 101: EKAKQMWSDM IQWRKDFGAD TIIEDFDFEE IDEVMKHYPQ GYHGVDKEGR PVYIERLGQI DANKLLQVTT MDRYVKYHVK EFEKTFKVKF PSCSVAANKH 201: IDQSTTILDV QGVGLKNFSK SARELLQRLC KIDNENYPET LNRMFIINAG SGFRLLWSTV KSFLDPKTTA KIHVLGNKYH SKLLEVIDAS ELPEFFGGAC 301: TCEDKGGCMR SDKGPWNDPE VLKIAINREA KCSPISEDEH KHVDQGRSTS GFESLERIKK KTDEDNVYEK QIATIDKSMD MAWLAKTQKA ENFPISKGLE 401: CYVRKGAPKK GDGLLVGGVM AFVMGIVAMV RLSKDVPRKL TEAALYGNSV CYEESTKSKQ NQGQFAAPVS SSEYMLMVKR MAELEDKCMF LDLKPAHVES 501: EKEEKLQAAL NRVQVLEQEL TETKKALEEA LVSQKEILAY IEKKKKKKKL FFGF |
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| See Also |
|
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Citation
If you find this resource useful please cite one of the following publications:
Hooper CM, Castleden I, Tanz SK, Aryamanesh, and Millar, AH (2017) SUBA4: the interactive data analysis centre for Arabidopsis subcellular protein locations Nucleic Acids Res. Jan 4;45(D1):D1064-D1074. doi: 10.1093/nar/gkw1041 (PubMed)
Hooper CM, Tanz SK, Castleden IR, Vacher MA, Small ID, Millar AH (2014) "SUBAcon: a consensus algorithm for unifying the subcellular localization data of the Arabidopsis proteome. Bioinformatics." 1;30(23):3356-64. (Bioinformatics) (PubMed)