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AT4G34520.1
Subcellular Consensus
(Prediction and Experimental)
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SUBAcon:
plasma membrane 0.887
What is SUBAcon?
Experimental Localisations and PPI
FP MS/MS PPI
SUBAcon links
AGI-AGI relationships
Coexpression PPI
no PPI data
Description (TAIR10) protein_coding : 3-ketoacyl-CoA synthase 18
Curator
Summary (TAIR10)
Encodes KCS18, a member of the 3-ketoacyl-CoA synthase family involved in the biosynthesis of VLCFA (very long chain fatty acids).
Computational
Description (TAIR10)
3-ketoacyl-CoA synthase 18 (KCS18); FUNCTIONS IN: fatty acid elongase activity, acyltransferase activity; INVOLVED IN: fatty acid elongation, very long-chain fatty acid metabolic process; LOCATED IN: endomembrane system, membrane; EXPRESSED IN: shoot apex, stem, fruit, carpel; EXPRESSED DURING: petal differentiation and expansion stage; CONTAINS InterPro DOMAIN/s: Thiolase-like (InterPro:IPR016039), Very-long-chain 3-ketoacyl-CoA synthase (InterPro:IPR012392), 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C-terminal (InterPro:IPR013747), FAE1/Type III polyketide synthase-like protein (InterPro:IPR013601), Thiolase-like, subgroup (InterPro:IPR016038); BEST Arabidopsis thaliana protein match is: 3-ketoacyl-CoA synthase 9 (TAIR:AT2G16280.1); Has 5011 Blast hits to 4998 proteins in 1240 species: Archae - 0; Bacteria - 1718; Metazoa - 0; Fungi - 14; Plants - 3124; Viruses - 0; Other Eukaryotes - 155 (source: NCBI BLink).
Protein Annotations
BioCyc:ARA:AT4G34520-MONOMERBioCyc:MetaCyc:AT4G34520-MONOMERChEMBL:CHEMBL2242735EC:2.3.1.199
eggNOG:COG3424eggNOG:ENOG410JUETEMBL:AL023094EMBL:AL161585
EMBL:CP002687EMBL:U29142EnsemblPlants:AT4G34520EnsemblPlants:AT4G34520.1
entrez:829603Gene3D:3.40.47.10GeneID:829603Genevisible:Q38860
GO:GO:0005783GO:GO:0006633GO:GO:0009922GO:GO:0016021
GO:GO:0031090Gramene:AT4G34520.1gramene_pathway:2.3.1.-gramene_pathway:PWY-5080
hmmpanther:PTHR31561HOGENOM:HOG000238893InParanoid:Q38860InterPro:IPR012392
InterPro:IPR013601InterPro:IPR013747InterPro:IPR016039iPTMnet:Q38860
KEGG:00061+2.3.1.180KEGG:00062+2.3.1.199KEGG:ath:AT4G34520KO:K15397
OMA:PPRKTFAPANTHER:PTHR31561PaxDb:Q38860Pfam:PF08392
Pfam:PF08541Pfam:Q38860PhylomeDB:Q38860PIR:T05272
PIRSF:PIRSF036417PRIDE:Q38860PRO:PR:Q38860ProteinModelPortal:Q38860
Proteomes:UP000006548RefSeq:NP_195178.1SMR:Q38860STRING:3702.AT4G34520.1
SUPFAM:SSF53901TAIR:AT4G34520tair10-symbols:FAE1tair10-symbols:KCS18
TMHMM:TMhelixUniGene:At.26989UniPathway:UPA00094UniProt:Q38860
Coordinates (TAIR10) chr4:+:16494205..16495725
Molecular Weight (calculated) 56267.10 Da
IEP (calculated) 9.77
GRAVY (calculated) -0.05
Length 506 amino acids
Sequence (TAIR10)
(BLAST)
001: MTSVNVKLLY RYVLTNFFNL CLFPLTAFLA GKASRLTIND LHNFLSYLQH NLITVTLLFA FTVFGLVLYI VTRPNPVYLV DYSCYLPPPH LKVSVSKVMD
101: IFYQIRKADT SSRNVACDDP SSLDFLRKIQ ERSGLGDETY SPEGLIHVPP RKTFAASREE TEKVIIGALE NLFENTKVNP REIGILVVNS SMFNPTPSLS
201: AMVVNTFKLR SNIKSFNLGG MGCSAGVIAI DLAKDLLHVH KNTYALVVST ENITQGIYAG ENRSMMVSNC LFRVGGAAIL LSNKSGDRRR SKYKLVHTVR
301: THTGADDKSF RCVQQEDDES GKIGVCLSKD ITNVAGTTLT KNIATLGPLI LPLSEKFLFF ATFVAKKLLK DKIKHYYVPD FKLAVDHFCI HAGGRAVIDE
401: LEKNLGLSPI DVEASRSTLH RFGNTSSSSI WYELAYIEAK GRMKKGNKAW QIALGSGFKC NSAVWVALRN VKASANSPWQ HCIDRYPVKI DSDLSKSKTH
501: VQNGRS
See Also
Citation
If you find this resource useful please cite one of the following publications:

Hooper CM, Castleden I, Tanz SK, Aryamanesh, and Millar, AH (2017) SUBA4: the interactive data analysis centre for Arabidopsis subcellular protein locations Nucleic Acids Res. Jan 4;45(D1):D1064-D1074. doi: 10.1093/nar/gkw1041 (PubMed)

Hooper CM, Tanz SK, Castleden IR, Vacher MA, Small ID, Millar AH (2014) "SUBAcon: a consensus algorithm for unifying the subcellular localization data of the Arabidopsis proteome. Bioinformatics." 1;30(23):3356-64. (Bioinformatics) (PubMed)