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AT4G34460.1
Subcellular Consensus
(Prediction and Experimental)

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SUBAcon:
endoplasmic reticulum 0.500
plasma membrane 0.500
ASURE: endoplasmic reticulum,plasma membrane
What is SUBAcon?
What is ASURE?
SUBAcon computations
Experimental Localisations and PPI
FP MS/MS PPI
SUBAcon links
AGI-AGI relationships
Coexpression PPI
Description (TAIR10) protein_coding : GTP binding protein beta 1
Curator
Summary (TAIR10)
Encodes the heterotrimeric G-protein beta subunit and is involved in organ shape. A significant fraction of the protein is found in the ER. Mutants carrying null alleles express similar fruit phenotypes, as seen in er plants, but differ from er in that the stem is only slightly shorter than that in the wild type, the pedicel is slightly longer than that in the wild type, and the leaves are rounder than those in er mutants. Gene is expressed in all tissues examined, with highest expression level found in siliques. It is involved in resistance to Plectosphaerella cucumerina. The predicted protein has two DWD motifs. It can bind to DDB1a in Y2H assays and may be involved in the formation of a CUL4-based E3 ubiquitin ligase
Computational
Description (TAIR10)
GTP binding protein beta 1 (AGB1); FUNCTIONS IN: protein binding, GTPase activity, nucleotide binding; INVOLVED IN: in 11 processes; LOCATED IN: endoplasmic reticulum, plasma membrane, CUL4 RING ubiquitin ligase complex, heterotrimeric G-protein complex; EXPRESSED IN: 26 plant structures; EXPRESSED DURING: 14 growth stages; CONTAINS InterPro DOMAIN/s: WD40 repeat 2 (InterPro:IPR019782), WD40 repeat, conserved site (InterPro:IPR019775), Guanine nucleotide-binding protein, beta subunit (InterPro:IPR016346), WD40 repeat (InterPro:IPR001680), G-protein beta WD-40 repeat, region (InterPro:IPR020472), G-protein, beta subunit (InterPro:IPR001632), WD40 repeat-like-containing domain (InterPro:IPR011046), WD40-repeat-containing domain (InterPro:IPR017986), WD40/YVTN repeat-like-containing domain (InterPro:IPR015943), WD40 repeat, subgroup (InterPro:IPR019781); BEST Arabidopsis thaliana protein match is: WD-40 repeat family protein (TAIR:AT5G67320.1); Has 60281 Blast hits to 28762 proteins in 834 species: Archae - 58; Bacteria - 8505; Metazoa - 23635; Fungi - 12687; Plants - 7683; Viruses - 0; Other Eukaryotes - 7713 (source: NCBI BLink).
Protein Annotations
BioCyc:ARA:AT4G34460-MONOMERBioGrid:14879DIP:DIP-40108NeggNOG:ENOG410XQUXeggNOG:KOG0286EMBL:AL023094EMBL:AL161585
EMBL:CP002687EMBL:U12232EnsemblPlants:AT4G34460EnsemblPlants:AT4G34460.1entrez:829597ExpressionAtlas:P49177Gene3D:2.130.10.10
GeneID:829597Genevisible:P49177GO:GO:0003924GO:GO:0004871GO:GO:0005737GO:GO:0005783GO:GO:0005834
GO:GO:0005886GO:GO:0009723GO:GO:0009738GO:GO:0009788GO:GO:0009817GO:GO:0009845GO:GO:0009867
GO:GO:0009887GO:GO:0009991GO:GO:0010154GO:GO:0030968GO:GO:0048364GO:GO:0048527GO:GO:0050832
GO:GO:0072593GO:GO:0080008GO:GO:2000280hmmpanther:PTHR19850HOGENOM:HOG000176356InParanoid:P49177IntAct:P49177
InterPro:IPR001632InterPro:IPR001680InterPro:IPR015943InterPro:IPR016346InterPro:IPR017986InterPro:IPR019775InterPro:IPR020472
ncoils:CoilOMA:QVYQPHGPANTHER:PTHR19850PaxDb:P49177Pfam:P49177Pfam:PF00400Pfscan:PS50082
Pfscan:PS50294PhylomeDB:P49177PIR:T05266PRIDE:P49177PRINTS:PR00319PRINTS:PR00320PRO:PR:P49177
PROSITE:PS00678PROSITE:PS50082PROSITE:PS50294ProteinModelPortal:P49177Proteomes:UP000006548RefSeq:NP_195172.1scanprosite:PS00678
SMART:SM00320SMR:P49177STRING:3702.AT4G34460.1SUPFAM:SSF50978TAIR:AT4G34460tair10-symbols:AGB1tair10-symbols:ATAGB1
tair10-symbols:ELK4UniGene:At.22855UniProt:P49177
Coordinates (TAIR10) chr4:-:16477393..16479266
Molecular Weight (calculated) 41008.00 Da
IEP (calculated) 7.26
GRAVY (calculated) -0.22
Length 377 amino acids
Sequence (TAIR10)
(BLAST)
001: MSVSELKERH AVATETVNNL RDQLRQRRLQ LLDTDVARYS AAQGRTRVSF GATDLVCCRT LQGHTGKVYS LDWTPERNRI VSASQDGRLI VWNALTSQKT
101: HAIKLPCAWV MTCAFSPNGQ SVACGGLDSV CSIFSLSSTA DKDGTVPVSR MLTGHRGYVS CCQYVPNEDA HLITSSGDQT CILWDVTTGL KTSVFGGEFQ
201: SGHTADVLSV SISGSNPNWF ISGSCDSTAR LWDTRAASRA VRTFHGHEGD VNTVKFFPDG YRFGTGSDDG TCRLYDIRTG HQLQVYQPHG DGENGPVTSI
301: AFSVSGRLLF AGYASNNTCY VWDTLLGEVV LDLGLQQDSH RNRISCLGLS ADGSALCTGS WDSNLKIWAF GGHRRVI
See Also
Citation
If you find this resource useful please cite one of the following publications:

Hooper CM, Castleden I, Tanz SK, Aryamanesh, and Millar, AH (2017) SUBA4: the interactive data analysis centre for Arabidopsis subcellular protein locations Nucleic Acids Res. Jan 4;45(D1):D1064-D1074. doi: 10.1093/nar/gkw1041 (PubMed)

Hooper CM, Tanz SK, Castleden IR, Vacher MA, Small ID, Millar AH (2014) "SUBAcon: a consensus algorithm for unifying the subcellular localization data of the Arabidopsis proteome. Bioinformatics." 1;30(23):3356-64. (Bioinformatics) (PubMed)