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AT4G29810.1
Subcellular Consensus
(Prediction and Experimental)

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SUBAcon:
cytosol 0.965
What is SUBAcon?
What is ASURE?
SUBAcon computations
Experimental Localisations and PPI
FP MS/MS PPI
  • PMID:25900983 (2015): Golgi
  • PMID:25900983 (2015): Golgi Golgi apparatus Golgi membrane
  • PMID:25900983 (2015): Golgi trans-Golgi network
  • PMID:25900983 (2015): Golgi trans-Golgi network early endosome
  • PMID:25900983 (2015): Golgi trans-Golgi network multivesicular body
  • PMID:25900983 (2015): plant-type vacuole plant-type vacuole membrane
  • PMID:17317660 (2007): plasma membrane
SUBAcon links
AGI-AGI relationships
Coexpression PPI
Description (TAIR10) protein_coding : MAP kinase kinase 2
Curator
Summary (TAIR10)
encodes a MAP kinase kinase 2 that regulates MPK6 and MPK4 in response to cold and salt stresses. Co-expression with MEKK1 in protoplasts activated MKK2 activity, suggesting that MEKK1 may be a regulator of MKK2.
Computational
Description (TAIR10)
MAP kinase kinase 2 (MKK2); FUNCTIONS IN: MAP kinase kinase activity, kinase activity; INVOLVED IN: cold acclimation, MAPKKK cascade, response to salt stress, response to cold, defense response, incompatible interaction; LOCATED IN: plasma membrane, cytoplasm; EXPRESSED IN: 23 plant structures; EXPRESSED DURING: 13 growth stages; CONTAINS InterPro DOMAIN/s: Protein kinase, ATP binding site (InterPro:IPR017441), Serine/threonine-protein kinase domain (InterPro:IPR002290), Serine/threonine-protein kinase-like domain (InterPro:IPR017442), Serine/threonine-protein kinase, active site (InterPro:IPR008271), Protein kinase-like domain (InterPro:IPR011009), Protein kinase, catalytic domain (InterPro:IPR000719), Tyrosine-protein kinase, catalytic domain (InterPro:IPR020635); BEST Arabidopsis thaliana protein match is: MAP kinase/ ERK kinase 1 (TAIR:AT4G26070.3); Has 131554 Blast hits to 129384 proteins in 4297 species: Archae - 179; Bacteria - 15130; Metazoa - 48544; Fungi - 12993; Plants - 32706; Viruses - 527; Other Eukaryotes - 21475 (source: NCBI BLink).
Protein Annotations
BioCyc:ARA:AT4G29810-MONOMERBioCyc:ARA:GQT-2175-MONOMERBioCyc:ARA:GQT-2176-MONOMERBioGrid:14390EC:2.7.12.2eggNOG:ENOG410XQ5AeggNOG:KOG0581
EMBL:AB015313EMBL:AF067792EMBL:AF385688EMBL:AJ006871EMBL:AL050352EMBL:AL161575EMBL:AY078009
EMBL:CP002687EnsemblPlants:AT4G29810EnsemblPlants:AT4G29810.1entrez:829103ExpressionAtlas:Q9S7U9GeneID:829103Genevisible:Q9S7U9
GO:GO:0000165GO:GO:0000187GO:GO:0004674GO:GO:0004708GO:GO:0005524GO:GO:0005737GO:GO:0005886
GO:GO:0006468GO:GO:0007346GO:GO:0009409GO:GO:0009631GO:GO:0009651GO:GO:0009814GO:GO:0010051
GO:GO:0031098GO:GO:0045087GO:GO:0060918hmmpanther:PTHR24361hmmpanther:PTHR24361:SF385HOGENOM:HOG000234206InParanoid:Q9S7U9
IntAct:Q9S7U9InterPro:IPR000719InterPro:IPR008271InterPro:IPR011009InterPro:IPR017441iPTMnet:Q9S7U9KEGG:ath:AT4G29810
KO:K04368OMA:ELMFGCPPaxDb:Q9S7U9Pfam:PF00069Pfam:Q9S7U9Pfscan:PS50011PhylomeDB:Q9S7U9
PIR:T08542PIR:T51735PRIDE:Q9S7U9PRO:PR:Q9S7U9PROSITE:PS00107PROSITE:PS00108PROSITE:PS50011
ProteinModelPortal:Q9S7U9Proteomes:UP000006548Reactome:R-ATH-110056Reactome:R-ATH-112411Reactome:R-ATH-2559580Reactome:R-ATH-445144Reactome:R-ATH-450302
Reactome:R-ATH-450321Reactome:R-ATH-5674135Reactome:R-ATH-5674499RefSeq:NP_001031751.1RefSeq:NP_194710.1scanprosite:PS00107scanprosite:PS00108
SMART:SM00220SMR:Q9S7U9STRING:3702.AT4G29810.2SUPFAM:SSF56112TAIR:AT4G29810tair10-symbols:ATMKK2tair10-symbols:MK1
tair10-symbols:MKK2UniGene:At.1001UniGene:At.24272UniProt:Q9S7U9
Coordinates (TAIR10) chr4:-:14593299..14595241
Molecular Weight (calculated) 39850.70 Da
IEP (calculated) 6.40
GRAVY (calculated) -0.13
Length 363 amino acids
Sequence (TAIR10)
(BLAST)
001: MKKGGFSNNL KLAIPVAGEQ SITKFLTQSG TFKDGDLRVN KDGVRIISQL EPEVLSPIKP ADDQLSLSDL DMVKVIGKGS SGVVQLVQHK WTGQFFALKV
101: IQLNIDEAIR KAIAQELKIN QSSQCPNLVT SYQSFYDNGA ISLILEYMDG GSLADFLKSV KAIPDSYLSA IFRQVLQGLI YLHHDRHIIH RDLKPSNLLI
201: NHRGEVKITD FGVSTVMTNT AGLANTFVGT YNYMSPERIV GNKYGNKSDI WSLGLVVLEC ATGKFPYAPP NQEETWTSVF ELMEAIVDQP PPALPSGNFS
301: PELSSFISTC LQKDPNSRSS AKELMEHPFL NKYDYSGINL ASYFTDAGSP LATLGNLSGT FSV
See Also
Citation
If you find this resource useful please cite one of the following publications:

Hooper CM, Castleden I, Tanz SK, Aryamanesh, and Millar, AH (2017) SUBA4: the interactive data analysis centre for Arabidopsis subcellular protein locations Nucleic Acids Res. Jan 4;45(D1):D1064-D1074. doi: 10.1093/nar/gkw1041 (PubMed)

Hooper CM, Tanz SK, Castleden IR, Vacher MA, Small ID, Millar AH (2014) "SUBAcon: a consensus algorithm for unifying the subcellular localization data of the Arabidopsis proteome. Bioinformatics." 1;30(23):3356-64. (Bioinformatics) (PubMed)