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AT4G24460.1
Subcellular Consensus
(Prediction and Experimental)
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SUBAcon:
plastid 1.000
What is SUBAcon?
Experimental Localisations and PPI
FP MS/MS PPI
SUBAcon links
AGI-AGI relationships
Coexpression PPI
Description (TAIR10) protein_coding : CRT (chloroquine-resistance transporter)-like transporter 2
Curator
Summary (TAIR10)
Encodes one of the CRT-Like transporters (CLT1/AT5G19380, CLT2/AT4G24460, CLT3/AT5G12170). Required for glutathione homeostasis and stress responses. Mutants lacking these transporters are heavy metal-sensitive, glutathione(GSH)-deficient, and hypersensitive to Phytophthora infection.
Computational
Description (TAIR10)
CRT (chloroquine-resistance transporter)-like transporter 2 (CLT2); INVOLVED IN: response to cadmium ion, defense response to oomycetes, glutathione transport; LOCATED IN: chloroplast, plastid; EXPRESSED IN: 23 plant structures; EXPRESSED DURING: 15 growth stages; CONTAINS InterPro DOMAIN/s: Chloroquine resistance transporter related (InterPro:IPR013936); BEST Arabidopsis thaliana protein match is: CRT (chloroquine-resistance transporter)-like transporter 3 (TAIR:AT5G12170.2); Has 203 Blast hits to 201 proteins in 65 species: Archae - 2; Bacteria - 34; Metazoa - 4; Fungi - 0; Plants - 75; Viruses - 0; Other Eukaryotes - 88 (source: NCBI BLink).
Protein Annotations
eggNOG:ENOG410IJNWeggNOG:ENOG4111Y30EMBL:AK228633EMBL:AL078637
EMBL:AL161561EMBL:BT005771EMBL:BT029757EMBL:CP002687
EnsemblPlants:AT4G24460EnsemblPlants:AT4G24460.1EnsemblPlants:AT4G24460.2entrez:828548
GeneID:828548Genevisible:A1L4X0GO:GO:0002229GO:GO:0009507
GO:GO:0009536GO:GO:0016021GO:GO:0031969GO:GO:0034635
GO:GO:0046686hmmpanther:PTHR31326hmmpanther:PTHR31326:SF1HOGENOM:HOG000220923
InParanoid:A1L4X0InterPro:IPR013936KEGG:ath:AT4G24460OMA:LVPMKQY
PaxDb:A1L4X0Pfam:PF08627PhylomeDB:A1L4X0PIR:T09909
PRIDE:A1L4X0PRO:PR:A1L4X0ProteinModelPortal:A1L4X0Proteomes:UP000006548
RefSeq:NP_001190820.1RefSeq:NP_194177.2STRING:3702.AT4G24460.1SUPFAM:0043518
TAIR:AT4G24460tair10-symbols:CLT2TMHMM:TMhelixUniGene:At.32342
UniProt:A1L4X0
Coordinates (TAIR10) chr4:+:12642888..12645310
Molecular Weight (calculated) 46687.30 Da
IEP (calculated) 10.35
GRAVY (calculated) 0.65
Length 431 amino acids
Sequence (TAIR10)
(BLAST)
001: MDTVLMATTP PIRCLHASIP TVFRSPAIYQ VSCRSSQLFS YRSTTMMSMC FLRRSDLRSR FLSTPKTTSP MRRPRFSVGA STEESSIPSN RNLIVANSVV
101: IVALAVANRV LYKLALVPMK QYPFFMAQLT TFGYVLIYFT ILYTRRRLGI VTNEMMDVPK WRFAIIGFLE ALGVATGMAA AAMLPGPVIP ILNQTYLVWQ
201: LLFALLILGR RFLLNQIAGC LLVAVGVVVA VSSGSGADTT LSGIGFLWPA VLVASAAFQA GASIIKEFVF NDAAKRLEGK SLDIFVVNSF GSGFQALFVF
301: LLLPFLSNLK GIPFASLPSY LKDGAGCFFN TGAKISGCDG APILPLLYIS TNLAFNISLL HLVKISSAIV SSLTMMLSVP LAVYIMSKPL PYLPGGSSLS
401: SNFTMGCIVL VLGLLLYNIP TTPTKQHTKT S
See Also
Citation
If you find this resource useful please cite one of the following publications:

Hooper CM, Castleden I, Tanz SK, Aryamanesh, and Millar, AH (2017) SUBA4: the interactive data analysis centre for Arabidopsis subcellular protein locations Nucleic Acids Res. Jan 4;45(D1):D1064-D1074. doi: 10.1093/nar/gkw1041 (PubMed)

Hooper CM, Tanz SK, Castleden IR, Vacher MA, Small ID, Millar AH (2014) "SUBAcon: a consensus algorithm for unifying the subcellular localization data of the Arabidopsis proteome. Bioinformatics." 1;30(23):3356-64. (Bioinformatics) (PubMed)