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AT4G24250.1
Subcellular Consensus
(Prediction and Experimental)
min: heatmap :max

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SUBAcon:
plasma membrane 1.000
ASURE: plasma membrane
What is SUBAcon?
Experimental Localisations and PPI
FP MS/MS PPI
SUBAcon links
AGI-AGI relationships
Coexpression PPI
no coexpression data no PPI data
Description (TAIR10) protein_coding : Seven transmembrane MLO family protein
Curator
Summary (TAIR10)
A member of a large family of seven-transmembrane domain proteins specific to plants, homologs of the barley mildew resistance locus o (MLO) protein. The Arabidopsis genome contains 15 genes encoding MLO proteins, with localization in plasma membrane. Phylogenetic analysis revealed four clades of closely-related AtMLO genes. ATMLO13 belongs to the clade II, with ATMLO1 and ATMLO15. The gene is expressed during early seedling growth, in root and cotyledon vascular system, in pollen and also in placenta of developing siliques, as shown by GUS activity patterns. The expression of several phylogenetically closely-related AtMLO genes showed similar or overlapping tissue specificity and analogous responsiveness to external stimuli, suggesting functional redundancy, co-function, or antagonistic function(s).
Computational
Description (TAIR10)
MILDEW RESISTANCE LOCUS O 13 (MLO13); FUNCTIONS IN: calmodulin binding; INVOLVED IN: cell death, defense response; LOCATED IN: integral to membrane, plasma membrane; EXPRESSED IN: 13 plant structures; EXPRESSED DURING: seedling growth, petal differentiation and expansion stage; CONTAINS InterPro DOMAIN/s: Mlo-related protein (InterPro:IPR004326); BEST Arabidopsis thaliana protein match is: Seven transmembrane MLO family protein (TAIR:AT4G02600.2); Has 30201 Blast hits to 17322 proteins in 780 species: Archae - 12; Bacteria - 1396; Metazoa - 17338; Fungi - 3422; Plants - 5037; Viruses - 0; Other Eukaryotes - 2996 (source: NCBI BLink).
Protein Annotations
eggNOG:ENOG410IFDJeggNOG:ENOG410ZUVBEMBL:AK221618EMBL:BT026373
EnsemblPlants:AT4G24250EnsemblPlants:AT4G24250.1entrez:828526ExpressionAtlas:Q56XQ5
GeneID:828526GO:GO:0006952GO:GO:0009607GO:GO:0016021
Gramene:AT4G24250.1hmmpanther:PTHR31942hmmpanther:PTHR31942:SF19InParanoid:Q94KB2
InterPro:IPR004326KEGG:ath:AT4G24250KO:K08472OMA:SISWYLW
Pfam:PF03094Pfam:Q94KB2PhylomeDB:Q56XQ5RefSeq:NP_567697.1
STRING:3702.AT4G24250.1TAIR:AT4G24250tair10-symbols:ATMLO13tair10-symbols:MLO13
TMHMM:TMhelixUniGene:At.3456UniProt:Q56XQ5UniProt:Q94KB2
Coordinates (TAIR10) chr4:-:12575008..12577517
Molecular Weight (calculated) 55071.40 Da
IEP (calculated) 8.76
GRAVY (calculated) 0.17
Length 478 amino acids
Sequence (TAIR10)
(BLAST)
001: MAEARSGSLE YTPTWVVAFI CFIIVLLSLL AERGLHHLGK CLKRRQQDAL FEALQKLKEE LMLLGFISLM LTVSQAAIRH ICVPPALVNN MFPCKKPLEE
101: HHAPKSSHSI INNARHLLST GESPDHCAAK GQVPLVSVEA LHQLHIFIFV LAVFHVIFCA STMVLGGARI QQWKHWEDWF KKRPSQKGTT RRGHHAHAHE
201: LFSANHEFFE MHAGGFWRRS VVISWVRSFF KQFYGSVTKS EYIALRQAFI MSHCRTNPSF DFHKYMLRTL EIDFKKVVSI SWYLWLFVVV FLLLNVGGWN
301: TYFWLSFLPL ILLLMVGAKL EYIISSLALD VSEKRSRAEE AVITPSDELF WFHRPGIVLQ LIHFILFQNS FEIAFFFWIL FTYGIHSCIM EKLGYLIPRL
401: VMGVLVQVLC SYSTLPLYAL VTQMGSKFKK GIFDNVVQST LEGWLEDTRN RGESTSEAHR IEMQPTTPES YNVQSENP
See Also
Citation
If you find this resource useful please cite one of the following publications:

Hooper CM, Castleden I, Tanz SK, Aryamanesh, and Millar, AH (2017) SUBA4: the interactive data analysis centre for Arabidopsis subcellular protein locations Nucleic Acids Res. Jan 4;45(D1):D1064-D1074. doi: 10.1093/nar/gkw1041 (PubMed)

Hooper CM, Tanz SK, Castleden IR, Vacher MA, Small ID, Millar AH (2014) "SUBAcon: a consensus algorithm for unifying the subcellular localization data of the Arabidopsis proteome. Bioinformatics." 1;30(23):3356-64. (Bioinformatics) (PubMed)