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AT4G24190.1
Subcellular Consensus
(Prediction and Experimental)
min: heatmap :max

.
SUBAcon:
endoplasmic reticulum 1.000
ASURE: endoplasmic reticulum
What is SUBAcon?
Predictors External Curations
AmiGO : endoplasmic reticulum 11867518
AmiGO : endoplasmic reticulum 16618929
AmiGO : endoplasmic reticulum 17059403
AmiGO : mitochondrion 14671022
SwissProt : endoplasmic reticulum 16381842
TAIR : plastid 15028209
TAIR : vacuole 15539469
TAIR : nucleus 14617066
TAIR : plastid 18431481
TAIR : plasma membrane 17644812
TAIR : mitochondrion 14671022
TAIR : endoplasmic reticulum 11867518
Experimental Localisations and PPI
FP MS/MS PPI
  • PMID:18931141 (2008): endoplasmic reticulum
  • PMID:31818904 (2020): mitochondrion
  • PMID:31615849 (2019): plastid plastid thylakoid
  • PMID:31520498 (2020): mitochondrion
  • PMID:31023727 (2019): mitochondrion
  • PMID:30962257 (2019): plastid
  • PMID:30961429 (2019): nucleus
  • PMID:30783145 (2019): extracellular region plant-type cell wall
  • PMID:30447334 (2019): plasma membrane
  • PMID:28865150 (2017): extracellular region plant-type cell wall
  • PMID:27943495 (2017): mitochondrion
  • PMID:27177187 (2016): nucleus
  • PMID:26781341 (2016): plasma membrane
  • PMID:26572690 (2016): extracellular region plant-type cell wall
  • PMID:25900983 (2015): plant-type vacuole plant-type vacuole membrane
  • PMID:25900983 (2015): Golgi trans-Golgi network multivesicular body
  • PMID:25900983 (2015): Golgi trans-Golgi network early endosome
  • PMID:25900983 (2015): Golgi trans-Golgi network
  • PMID:25900983 (2015): Golgi
  • PMID:25900983 (2015): Golgi Golgi apparatus Golgi membrane
  • PMID:25641898 (2015): plasma membrane
  • PMID:24727099 (2014): mitochondrion
  • PMID:24124904 (2013): plastid
  • PMID:23673981 (2013): plastid plastid stroma plastoglobules
  • PMID:23396599 (2013): nucleus nuclear envelope nuclear inner membrane
  • PMID:22923678 (2012): endoplasmic reticulum
  • PMID:22550958 (2012): plastid
  • PMID:22215637 (2012): plasma membrane
  • PMID:21988472 (2012): plant-type vacuole plant-type vacuole membrane
  • PMID:21533090 (2011): extracellular region plant-type cell wall
  • PMID:21433285 (2011): plasma membrane
  • PMID:19334764 (2009): plasma membrane
  • PMID:18431481 (2008): plastid
  • PMID:17644812 (2007): plasma membrane
  • PMID:17151019 (2007): plant-type vacuole
  • PMID:16618929 (2006): endoplasmic reticulum
  • PMID:15028209 (2004): plastid
  • PMID:14671022 (2004): mitochondrion
  • PMID:14617066 (2003): nucleus
FP Images

onion epidermal cell layer (peroxisomal marker)

At4g-GFP-24190
(full-length)
RFP-peroxisomal markeroverlay

Images by John Bussel
SUBAcon links
AGI-AGI relationships
Coexpression PPI
Description (TAIR10) protein_coding : Chaperone protein htpG family protein
Curator
Summary (TAIR10)
encodes an ortholog of GRP94, an ER-resident HSP90-like protein and is involved in regulation of meristem size and organization. Single and double mutant analyses suggest that SHD may be required for the correct folding and/or complex formation of CLV proteins. Lines carrying recessive mutations in this locus exhibits expanded shoot meristems, disorganized root meristems, and defective pollen tube elongation. Transcript is detected in all tissues examined and is not induced by heat. Endoplasmin supports the protein secretory pathway and has a role in proliferating tissues.
Computational
Description (TAIR10)
SHEPHERD (SHD); FUNCTIONS IN: unfolded protein binding, ATP binding; INVOLVED IN: in 8 processes; LOCATED IN: in 7 components; EXPRESSED IN: 25 plant structures; EXPRESSED DURING: 16 growth stages; CONTAINS InterPro DOMAIN/s: Chaperone protein htpG (InterPro:IPR001404), Heat shock protein Hsp90, C-terminal (InterPro:IPR020576), Heat shock protein Hsp90, N-terminal (InterPro:IPR020575), Molecular chaperone, heat shock protein, endoplasmin (InterPro:IPR015566), ATPase-like, ATP-binding domain (InterPro:IPR003594), Heat shock protein Hsp90, conserved site (InterPro:IPR019805), Ribosomal protein S5 domain 2-type fold (InterPro:IPR020568); BEST Arabidopsis thaliana protein match is: heat shock protein 90.1 (TAIR:AT5G52640.1); Has 10659 Blast hits to 10182 proteins in 2496 species: Archae - 7; Bacteria - 3605; Metazoa - 2791; Fungi - 470; Plants - 491; Viruses - 10; Other Eukaryotes - 3285 (source: NCBI BLink).
Protein Annotations
BioGrid:13809eggNOG:COG0326eggNOG:KOG0020EMBL:AB064528
EMBL:AC002343EMBL:AK221485EMBL:AL078637EMBL:AL161561
EMBL:AY039895EMBL:AY072394EMBL:BT004527EMBL:CP002687
EnsemblPlants:AT4G24190EnsemblPlants:AT4G24190.1entrez:828520ExpressionAtlas:Q9STX5
Gene3D:3.30.565.10GeneID:828520Genevisible:Q9STX5GO:GO:0005524
GO:GO:0005634GO:GO:0005739GO:GO:0005773GO:GO:0005774
GO:GO:0005783GO:GO:0005788GO:GO:0005886GO:GO:0006457
GO:GO:0009306GO:GO:0009409GO:GO:0009414GO:GO:0009506
GO:GO:0009507GO:GO:0009651GO:GO:0009934GO:GO:0010075
GO:GO:0016020GO:GO:0046686GO:GO:0048046HAMAP:MF_00505
hmmpanther:PTHR11528hmmpanther:PTHR11528:SF45HOGENOM:HOG000031988InParanoid:Q9STX5
IntAct:Q9STX5InterPro:IPR001404InterPro:IPR003594InterPro:IPR019805
InterPro:IPR020568InterPro:IPR020575iPTMnet:Q9STX5KEGG:ath:AT4G24190
KO:K09487ncoils:CoilOMA:RKPADVTPANTHER:PTHR11528
PaxDb:Q9STX5Pfam:PF00183Pfam:PF02518Pfam:Q9STX5
PhylomeDB:Q9STX5PIR:T09882PIRSF:PIRSF002583PRIDE:Q9STX5
PRINTS:PR00775PRO:PR:Q9STX5PROSITE:PS00014PROSITE:PS00298
ProteinModelPortal:Q9STX5Proteomes:UP000006548RefSeq:NP_194150.1scanprosite:PS00298
SMART:SM00387SMR:Q9STX5STRING:3702.AT4G24190.1SUPFAM:0043579
SUPFAM:SSF54211SUPFAM:SSF55874TAIR:AT4G24190tair10-symbols:AtHsp90-7
tair10-symbols:AtHsp90.7tair10-symbols:HSP90.7tair10-symbols:SHDUniGene:At.24111
UniProt:Q9STX5
Coordinates (TAIR10) chr4:-:12551902..12555851
Molecular Weight (calculated) 94208.80 Da
IEP (calculated) 4.66
GRAVY (calculated) -0.70
Length 823 amino acids
Sequence (TAIR10)
(BLAST)
001: MRKRTLVSVL FLFSLLFLLP DQGRKLHANA EESSDDVTDP PKVEEKIGGH GGLSTDSDVV HRESESMSKK TLRSNAEKFE FQAEVSRLMD IIINSLYSNK
101: DIFLRELISN ASDALDKIRF LALTDKDVLG EGDTAKLEIQ IKLDKAKKIL SIRDRGIGMT KEDLIKNLGT IAKSGTSAFV EKMQSSGDLN LIGQFGVGFY
201: SAYLVADYIE VISKHNDDSQ YVWESKANGK FAVSEDTWNE PLGRGTEIRL HLRDEAGEYL EESKLKELVK RYSEFINFPI SLWASKEVET EVPVEEDESA
301: DEETETTSTE EEKEEDAEEE DGEKKQKTKK VKETVYEWEL LNDVKAIWLR SPKEVTEEEY TKFYHSLSKD FTDEKPMAWS HFNAEGDVEF KAVLYVPPKA
401: PHDLYESYYN SNKANLKLYV RRVFISDEFD ELLPKYLSFL KGLVDSDTLP LNVSREMLQQ HSSLKTIKKK LIRKALDMIR KLAEEDPDEI HDDEKKDVEK
501: SGENDEKKGQ YTKFWNEFGK SVKLGIIEDA ANRNRLAKLL RFETTKSDGK LTSLDQYIKR MKKSQKDIFY ITGSSKEQLE KSPFLERLIK KGYEVIFFTD
601: PVDEYLMQYL MDYEDKKFQN VSKEGLKVGK DSKDKELKEA FKELTKWWKG NLASENVDDV KISNRLADTP CVVVTSKFGW SANMERIMQS QTLSDANKQA
701: YMRGKRVLEI NPRHPIIKEL KDRIASDPED ESVKETAQLM YQTALIESGF ILTDPKDFAA RIYNSVKSGL NISPDAVADE EIEAAEEPET SEATETKSDD
801: LAGGLNIEAE PVEQQEENTK DEL
See Also
Citation
If you find this resource useful please cite one of the following publications:

Hooper CM, Castleden I, Tanz SK, Aryamanesh, and Millar, AH (2017) SUBA4: the interactive data analysis centre for Arabidopsis subcellular protein locations Nucleic Acids Res. Jan 4;45(D1):D1064-D1074. doi: 10.1093/nar/gkw1041 (PubMed)

Hooper CM, Tanz SK, Castleden IR, Vacher MA, Small ID, Millar AH (2014) "SUBAcon: a consensus algorithm for unifying the subcellular localization data of the Arabidopsis proteome. Bioinformatics." 1;30(23):3356-64. (Bioinformatics) (PubMed)